Results 81 to 90 of about 16,132 (220)

Real-World Analysis of Switching Patients with Schizophrenia from Oral Risperidone or Oral Paliperidone to Once-Monthly Paliperidone Palmitate

Drugs - Real World Outcomes, 2019
Purpose Reducing the dosing frequency of antipsychotics (APs) with long-acting injectables (LAIs) such as once-monthly paliperidone palmitate (PP1M) can improve adherence and clinical outcomes for schizophrenia patients.
Charmi Patel, Bruno Emond, Marie-Hélène Lafeuille, Aurélie Côté-Sergent, Patrick Lefebvre, Neeta Tandon, Antoine C. El Khoury   +6 more
doaj   +1 more source

Disrupted Brain Structure and Function in Alzheimer's Disease Patients With Behavioral and Psychological Symptoms

iNew Medicine, EarlyView.
ABSTRACT Behavioral and psychological symptoms of dementia (BPSD) are highly prevalent in Alzheimer's disease (AD), but the underlying mechanisms are unclear. This study aims to elucidate the neuropathological mechanisms underlying BPSD by investigating gray matter volume (GMV) and brain connectivity in AD patients with and without BPSD.
Xuerui Pang, Linbo Xie, Mengdan Chen, Yi Ji, Yibing Yan, Shanshan Zhou, Panpan Hu, Xingqi Wu, Kai Wang   +8 more
wiley   +1 more source

Acute Modafinil Exposure Induces Neurobehavioral Alterations in Zebrafish: Implications for Off‐Label Cognitive Enhancement

Journal of Applied Toxicology, EarlyView.
ABSTRACT Modafinil (2‐(benzhydrylsulfinyl)acetamide) is a psychostimulant commonly prescribed for sleep disorders such as narcolepsy, excessive daytime sleepiness, and obstructive sleep apnea. Recently, its use has extended beyond clinical indications, with neurotypical individuals adopting it as a smart drug to enhance alertness and cognitive ...
Luciane Dellazari da Silva do Prado, Nicole Berton, Nicoli da Rosa Amaral, Inara Carbonera Biazus, Laíse Mattiollo, Jéssica Nardi, Karen Júlia de Souza dos Santos, Natália Freddo, Leonardo José Gil Barcellos, Luciana Grazziotin Rossato‐Grando   +9 more
wiley   +1 more source

Using Virtual Reality Social Environments to Promote Outcomes' Generalization of AVATAR Therapy for Distressing Voices: A Case Study

Journal of Clinical Psychology, Volume 81, Issue 6, Page 516-525, June 2025.
ABSTRACT AVATAR therapy (AT) works by facilitating a ‘face‐to‐face’ dialog between the person and a digital representation (avatar) of their persecutory voice. Although there is cumulative evidence of this way of working with voices, enhancing the therapeutic focus on improved confidence and a sense of control of the voices in social situations ...
Mar Rus‐Calafell, Nils Ehrbar, Tobias Teismann, Silvia Schneider, Ekincan Tas, Simon Schuster, Clementine Edwards, Mark Huckvale, Thomas Craig, Philippa Garety, Thomas Ward   +10 more
wiley   +1 more source

Deliberate Practice Supervision to Enhance the Effectiveness of Behavioral Activation for Depression: A Case Study

Journal of Clinical Psychology, Volume 81, Issue 6, Page 526-537, June 2025.
ABSTRACT Deliberate Practice (DP) is a model of behavioral skill acquisition structured by several key tasks. The past decade has shown a consistent growth in interest in this form of learning for psychotherapy skills, with promising research suggesting DP training is superior to traditional learning methods of psychotherapy. This paper presents a case
Dan Sacks
wiley   +1 more source

Sleep problems during the menopausal transition: prevalence, impact, and management challenges

Nature and Science of Sleep, 2018
Fiona C Baker,1,2 Massimiliano de Zambotti,1 Ian M Colrain,1,3 Bei Bei4,5 1Center for Health Sciences, SRI International, Menlo Park, CA, USA; 2Brain Function Research Group, University of the Witwatersrand, Johannesburg, South Africa; 3Melbourne School ...
Baker FC, de Zambotti M, Colrain IM, Bei B   +3 more
doaj  

Alexithymia in Schizophrenia and Psychosis Vulnerability: A Systematic Review and Meta‐Analysis

Journal of Clinical Psychology, Volume 81, Issue 6, Page 410-424, June 2025.
ABSTRACT Aims Disturbances involving impairments in experience and expression of affect are frequently identified in schizophrenia samples. Alexithymia underlies cognitive impairments in identification and expression of affect, further implicated in affect dysregulation.
Ercan Ozdemir, Zhuoni Xiao, Helen Griffiths, Angus MacBeth   +3 more
wiley   +1 more source

Infant frontal alpha asymmetry predicts social attention and transdiagnostic risk for emotional reactivity

JCPP Advances, EarlyView.
Abstract Background Differences in Frontal Alpha Asymmetry (FAA), derived from the electroencephalogram (EEG), have been associated with approach‐withdrawal behavior, although inconsistently. The current study examined how early patterns of FAA during the first 2 years of life relate to various socioemotional characteristics (at 2 years) and ultimately
Viviane Valdes, Niccola Lutri, Haerin Chung, Charles A. Nelson   +3 more
wiley   +1 more source

Sleep disturbance as a transdiagnostic marker of children's mental health difficulties: A network analysis of item‐level associations between different types of sleep problems and different behavioural and emotional symptoms

JCPP Advances, EarlyView.
Abstract Background Sleep disturbances are widely considered to be a transdiagnostic feature of common behavioural and emotional difficulties in childhood, yet most studies treat sleep as a single construct. Where studies have explored specific sleep problems to psychopathology in children, these tend to only include behavioural or emotional ...
Alina A. Marinca, Julia E. Michalek, Alice M. Gregory, Afia Ali, Jennifer Y. F. Lau   +4 more
wiley   +1 more source

From regulatory mechanisms to cutting‐edge applications: Research progress of ultrasound, electrical, magnetic, and optical stimulation in neural modulation

Journal of Intelligent Medicine, EarlyView.
Abstract In recent years, the clinical treatment and symptom management of neurological disorders have faced significant challenges due to the high complexity of the nervous system's structure and function. Against this backdrop, physical stimulation techniques have emerged as a vital complementary approach to traditional pharmacological treatments and
Wanying Li, Liqun Chen
wiley   +1 more source