Results 61 to 70 of about 16,132 (220)
Epilepsia, EarlyView.Abstract Children with developmental and epileptic encephalopathies (DEEs) face cognitive and behavioral challenges that may have a greater impact than seizures on their quality of life (QoL). The need to assess these nonseizure outcomes for evaluating treatments is increasingly recognized.
Cinzia Correale +9 more
wiley +1 more source
Sleep disturbances in SCN8A‐related disorders
Epilepsia OpenObjectives People with neurodevelopmental disorders frequently experience sleep disturbances, negatively impairing their quality of life. We aimed to determine the prevalence and nature of sleep disturbances in patients with SCN8A‐related disorders ...
Francesca Furia +15 more
doaj +1 more source
Epilepsia, EarlyView.Abstract Objective Epilepsy is a highly heterogeneous neurological disorder with significant prognostic variability. Accurate long‐term outcome prediction remains a clinical challenge. We investigated pharmacotherapeutic prognosis and key predictors, particularly baseline seizure timing, to guide individualized treatment.
Lei Sun +3 more
wiley +1 more source
Epilepsy syndromes classification
Epilepsia Open, EarlyView.Abstract Epilepsy syndromes are distinct electroclinical entities which have been recently defined by the International League Against Epilepsy Nosology and Definitions Task Force. Each syndrome is associated with “a characteristic cluster of clinical and EEG features, often supported by specific etiologic findings”.
Elaine C. Wirrell +4 more
wiley +1 more source
Absence seizures: Update on signaling mechanisms and networks
Epilepsia Open, EarlyView.Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Sleep Science, 2011 It is possible for normal subjects to fall asleep during daytime wakefulness, and the propensity for daytime sleep varies being high in the mid-afternoon and lower in the early evening 2 or 3 hours before overnight sleep onset.
José Carlos Pereira +1 more
doaj +1 more source
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Epilepsia Open, EarlyView.Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
Influence of social factors on the sleep-wake cycle in children
Sleep Science, 2010 In children, the sleep-wake cycle (SWC) is influenced by both social and biological factors. Recently, lifestyle changes have introduced a number of social factors that negatively impact sleeping patterns.
Aline Silva Belísio +2 more
doaj +1 more source
Unveiling sleep disturbances in KCNB1‐related disorders: Insights from a cohort of 78 individuals
Epilepsia Open, EarlyView.Abstract Objectives Sleep disturbances are frequent comorbidities in epilepsies and developmental encephalopathies. This study aimed to characterize sleep abnormalities in individuals with KCNB1‐related disorders, focusing on their prevalence, clinical manifestations, and impact on daily functioning.
Giovanna Scorrano +4 more
wiley +1 more source
Treatment of migraine with fremanezumab and sleep: A preliminary case series
Cephalalgia ReportsBackground Migraine is a prevalent neurological disease that has socioeconomic and functional impact. It is also frequently associated with sleep disorders.
Agustin Melo-Carrillo +4 more
doaj +1 more source