Results 71 to 80 of about 431,406 (214)

Impact of sleep apnea on alzheimer’s disease in relation to sex: an 8-year longitudinal follow-up study of a nationwide cohort

Alzheimer’s Research & Therapy
Background We aimed to investigate the association between sleep apnea and incident dementia (dementia of the Alzheimer type [DAT] and vascular dementia) and whether differences in the effects of sleep apnea on dementia depend on sex.
Su Jin Chung, Sung Hoon Kang, Minwoong Kang, Yunjin Choi, Yu Jeong Park, Hayom Kim, Kyungmi Oh, Seong-Beom Koh, Jung Bin Kim   +8 more
doaj   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Supine sleep and positional sleep apnea after acute ischemic stroke and intracerebral hemorrhage

Clinics, 2012
OBJECTIVE: Obstructive sleep apnea is frequent during the acute phase of stroke, and it is associated with poorer outcomes. A well-established relationship between supine sleep and obstructive sleep apnea severity exists in non-stroke patients.
Millene R. Camilo, Regina M. F. Fernandes, Heidi H. Sander, Fernando Nobre, Taiza Santos-Pontelli, Antonio C. dos Santos, Draulio B. de Araujo, João P. Leite, Octavio M. Pontes-Neto   +8 more
doaj   +1 more source

Poor sleep quality measured by polysomnography in non-obese asthmatic children with or without moderate to severe obstructive sleep apnea

, 2014
[[abstract]]Background The co-effect of asthma and obstructive sleep apnea (OSA) on sleep quality among children remained unclear. Objective To compare sleep quality and emotional/behavioral problems among asthmatic and non-asthmatic children with or ...
Teng, Yu-Kuei;Teng, Yu-Kuei;Chian, Li-Chi;Chiang, Li-Chi;Lue, Ko-Huang;Lue, Ko-Huang;Cha, Shen-Wen;Chang, Shen-Wen;Wang, Lee;Wang, Lee;李舒萍;Lee, Shu-Ping;Ting, Hua;Ting, Hua;李信達*
core  

Decreased galectin-1 levels in obstructive sleep apnea: a novel biomarker

, 2021
Objective: Obstructive sleep apnea (OSA) is a common disease, which may cause oxidative stress because of intermittent apnea/hypopnea attacks occurring during sleep.
İRİZ, AYŞE, Süleyman Cebeci, Muammer Melih Şahin, Ayşe İriz, Dincel, Aylin Sepici, Mehmet Düzlü, DÜZLÜ, MEHMET, Rabia Şemsi, Aylin Sepici Dinçel, Semsi, Rabia, ŞAHİN, MUAMMER MELİH, CEBECİ, SÜLEYMAN   +11 more
core   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

Economic evaluations of antiobesity medications: A systematic literature review

British Journal of Clinical Pharmacology, EarlyView.
The global prevalence of obesity is rising rapidly. With several antiobesity medications approved and many more in development, understanding their economic value is increasingly important. This study reviews full economic evaluations of approved antiobesity medications to assess cost‐effectiveness and inform reimbursement and access decisions.
Martina Jurković, Almir Fajkić, Andrea Katrin Faour, Mirna Momčilović, Petra Turčić, Andrej Belančić   +5 more
wiley   +1 more source

Nocturnal nasal obstruction is frequent and reduces sleep quality in patients with obstructive sleep apnea. [PDF]

, 2017
To access publisher's full text version of this article, please click on the hyperlink in Additional Links field or click on the hyperlink at the top of the page marked FilesThe prevalence and consequences of nasal obstruction in untreated obstructive ...
Bjørnsdottir, Erla, Morgan Andersson, Sigurdur Juliusson, Erla Bjørnsdottir, Andersson, Morgan, Maria Värendh, Erna S. Arnardottir, Hrubos-Strøm, Harald, Gislason, Thorarinn, Björnsdóttir, Erla, Juliusson, Sigurdur, Júlíusson, Sigurður, Arnardottir, Erna S., Arne Johannisson, Värendh, Maria, Harald Hrubos-Strøm, Arnardottir, Erna S, Arnardottir, Erna Sif, Johannisson, Arne, Thorarinn Gislason, Värendh, Maria,, Hrubos-Strøm, Harald,, Gislason, Thorarinn,, Andersson, Morgan,, Bjørnsdottir, Erla,, Johannisson, Arne,, Lund University., Arnardottir, Erna S.,, Juliusson, Sigurdur,   +28 more
core   +1 more source

Current Concepts in Pediatric Obstructive Sleep Apnea

, 2023
Obstructive sleep apnea (OSA) is described as intermittent partial or complete upper airway obstruction that can disrupt respiratory and ventilatory patterns during sleep [...
Manisha Witmans, Mary Anne Tablizo
core   +1 more source

Pharmacokinetics and safety of a modified‐release psilocybin formulation: A SAD Phase I trial in normal‐weight and overweight/obese participants

British Journal of Clinical Pharmacology, EarlyView.
Aims This study aimed to evaluate the safety, tolerability and pharmacokinetics of a novel oral modified‐release psilocybin formulation (REL‐P11) in normal‐weight and overweight/obese healthy adults and to assess its suitability for controlled, subperceptual exposure, in light of emerging evidence supporting serotonergic modulation in metabolic ...
Anna Signor, Stefano Comai, Gianfranco Pasut, Franco Folli, Marco Gentilucci, Negar Gharavi, Sofia Raitsin, Thuy Van Nguyen, Marco Pappagallo, Andrea Mattarei, Paolo L. Manfredi, Sara De Martin   +11 more
wiley   +1 more source