Results 91 to 100 of about 412,559 (261)

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

Symptoms of insomnia among patients with obstructive sleep apnea before and after two years of positive airway pressure treatment. [PDF]

, 2013
To assess the changes of insomnia symptoms among patients with obstructive sleep apnea (OSA) from starting treatment with positive airway pressure (PAP) to a 2-y follow-up.Longitudinal cohort study.Landspitali--The National University Hospital of Iceland.
Sigurdsson, Jón F, Kuna, Samuel T., Kuna, Samuel T, Pack, Allan I, Pack, Allan I., Benediktsdóttir, Bryndis, Björnsdóttir, Erla, Gislason, Thorarinn, Janson, Christer, Juliusson, Sigurdur, Sigurdsson, Jon F., Arnardottir, Erna S., Janson, Christer,, Arnardottir, Erna S, Perlis, Michael, Gehrman, Philip   +15 more
core   +1 more source

Improvement in obstructive sleep apnea in a child with Down syndrome with rapid palatal expansion

, 2022
Children with Down syndrome (DS) have distinct orofacial structures that predispose them to sleep-disordered breathing. The management options for obstructive sleep apnea include continuous positive airway pressure, adenotonsillectomy, mandibular ...
최은경, 최윤정, 조형주
core   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Poor sleep quality measured by polysomnography in non-obese asthmatic children with or without moderate to severe obstructive sleep apnea

, 2014
[[abstract]]Background The co-effect of asthma and obstructive sleep apnea (OSA) on sleep quality among children remained unclear. Objective To compare sleep quality and emotional/behavioral problems among asthmatic and non-asthmatic children with or ...
Teng, Yu-Kuei;Teng, Yu-Kuei;Chian, Li-Chi;Chiang, Li-Chi;Lue, Ko-Huang;Lue, Ko-Huang;Cha, Shen-Wen;Chang, Shen-Wen;Wang, Lee;Wang, Lee;李舒萍;Lee, Shu-Ping;Ting, Hua;Ting, Hua;李信達*
core  

Prevalence of insomnia disorder and sleep apnea in a sample of veterans at risk for cardiovascular disease

, 2021
STUDY OBJECTIVES: The objectives of this study were to examine the proportion of study participants screening positive for insomnia disorder and/or sleep apnea in veterans engaged in routine health care and known to be at risk for cardiovascular disease ...
Olsen, Maren, Bosworth, Hayden B., Ulmer, Christi S, McCant, Felicia, Bosworth, Hayden B, Ulmer, Christi S., Stechuchak, Karen M., Stechuchak, Karen M   +7 more
core   +1 more source

Semaglutide vs. liraglutide and incidence of diabetes and cardiovascular disease: A target trial emulation using real‐world data

British Journal of Clinical Pharmacology, EarlyView.
Aims The glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) semaglutide and liraglutide are approved for chronic weight management. Both drugs also have favourable effects on the risk of developing diabetes and cardiovascular disease (CVD) compared with placebo, but their comparative effectiveness for these outcomes is unclear.
Ethan J. Cannon, Wendy Wang, Faye L. Norby, Rob F. Walker, Shalini Kulasingam, Lisa S. Chow, Joel F. Farley, Pamela L. Lutsey   +7 more
wiley   +1 more source

The role of sleep in the psychological functioning of adolescents [PDF]

, 2016
Adolescents’ sleep is related to psychological functioning. The present cumulative dissertation examined three main issues: First, whether parents’ sleep patterns are associated with their adolescent children’ sleep Patterns using objective assessment of
Kalak, Nadeem
core   +1 more source

Hypertension in obesity: A focus on individualized pharmacotherapy and the role of body composition, on behalf of the European Society of Hypertension Working Group on Diabetes and Metabolic Risk Factors and Working Group on Lifestyle, Cardiovascular Pharmacotherapy and Adherence

British Journal of Clinical Pharmacology, EarlyView.
Hypertension in obesity represents a major global health challenge, closely linked to the global epidemics of obesity, type 2 diabetes and metabolic dysfunction. Excess adiposity contributes to elevated blood pressure through multiple, interrelated mechanisms, including activation of the renin–angiotensin–aldosterone system, sympathetic nervous system ...
Christina Antza, Andrej Belancic, Jens Jordan, Alberto Esteban, Anna Oliveras Serrano, Ryan McNally, Panagiota Anyfanti, Jorie Versmissen, María S. Fernández‐Alfonso, Vasilios Kotsis, Thomas Weber, Alexandre Persu, Reinhold Kreutz   +12 more
wiley   +1 more source

What Is the Pterygomandibular Raphe? A Confluence of Fasciae Rather Than a Discrete Structure

Clinical Anatomy, EarlyView.
ABSTRACT The pterygomandibular raphe (PMR) has traditionally been described as a fibrous or tendinous band connecting the bucinator (BM) and superior pharyngeal constrictor (SPCM) muscles. However, recent evidence has questioned its existence. This study aimed to reevaluate the anatomy of the pterygomandibular region by preserving fascial continuity ...
Joe Iwanaga, Shion Hama, Keiko Fukino, Shogo Kikuta, Mi‐Sun Hur, Maria Cristina Manzanares Cespedes, Yoshio Ohyama, Masaya Akashi, Noritaka Komune, Hideaki Kamochi, Soichiro Ibaragi   +10 more
wiley   +1 more source