Results 101 to 110 of about 214,324 (306)

Ixekizumab With Tirzepatide Achieved Greater Disease Control Than Ixekizumab Alone in Adults With Psoriatic Arthritis and Overweight or Obesity: Results From a Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective Overweight or obesity is prevalent in 72% to 82% of individuals with psoriatic arthritis (PsA). We assessed the efficacy and safety of ixekizumab (IXE) concomitantly administered with tirzepatide (TZP) compared with IXE alone in adult participants with active PsA and overweight with at least one weight‐related comorbidity or obesity.
Joseph F. Merola, Philip Mease, Alan Kivitz, Naveed Sattar, Laura C. Coates, Daniel Aletaha, Cynthia E. Kartman, Peter Fischer, Luna Sun, Píndaro Martínez‐Osuna, Andris Kronbergs, Purvi Prajapati, Anabela Cardoso, Mark C. Genovese, Alexis Ogdie   +14 more
wiley   +1 more source

Behavioral Incentives for Exercise and Intra‐Articular Glucocorticoids for Knee Osteoarthritis: Results From a Factorially Designed Pragmatic Randomized Clinical Trial

Arthritis &Rheumatology, EarlyView.
Objective The purpose of this study was to determine the benefit of a behaviorally designed incentive program and glucocorticoid injections in reducing symptoms and promoting physical activity in patients with knee osteoarthritis (KOA). Methods This was a pragmatic, multisite, factorially designed, blinded, randomized clinical trial.
Joshua F. Baker, Katherine D. Wysham, Mercedes Quinones, Bryant R. England, Kaitian Jin, Marianna Olave, Sarah Wetzel, Rachel L. Gillcrist, Criswell Lavery, Natalie Keller, Bridget Kramer, Bibianna Ateh, Hannah Brubeck, Daniel K. White, Alexis Ogdie, Rui Xiao, Tuhina Neogi, Carla R. Scanzello   +17 more
wiley   +1 more source

Obstructive sleep apnea syndrome in the pediatric age: the role of the dentist [PDF]

, 2019
Sleep disordered breathing in children designates a wide spectrum of respiratory disorders characterized by partial or complete obstruction of the upper airways.
Di Carlo, G, Ierardo, G, Luzzi, V, Polimeni, A, Saccucci, M   +4 more
core   +1 more source

Exposure‐adjusted safety and efficacy of GLP‐I and GLP‐1/GIP receptor agonists compared with non‐GLP‐I for weight management and type 2 diabetes: Based on FDA medical and statistical reports of 34 280 safety and 36 312 efficacy subjects

British Journal of Clinical Pharmacology, EarlyView.
Aims This work aimed to contextualize glucagon‐like peptide‐1 receptor agonists (GLP‐1 RAs) and glucose‐dependent insulinotropic polypeptide (GIP) receptor agonists safety and efficacy regarding weight management (WM); we analysed Food and Drug Administration (FDA) Medical Reviews to analyse 14 medications using patient‐exposure year normalization and ...
Aishwarya Prasad, Anshu Arora, Arun Arora, Jeena Vaid, Arif Khan   +4 more
wiley   +1 more source

What Is the Pterygomandibular Raphe? A Confluence of Fasciae Rather Than a Discrete Structure

Clinical Anatomy, EarlyView.
ABSTRACT The pterygomandibular raphe (PMR) has traditionally been described as a fibrous or tendinous band connecting the bucinator (BM) and superior pharyngeal constrictor (SPCM) muscles. However, recent evidence has questioned its existence. This study aimed to reevaluate the anatomy of the pterygomandibular region by preserving fascial continuity ...
Joe Iwanaga, Shion Hama, Keiko Fukino, Shogo Kikuta, Mi‐Sun Hur, Maria Cristina Manzanares Cespedes, Yoshio Ohyama, Masaya Akashi, Noritaka Komune, Hideaki Kamochi, Soichiro Ibaragi   +10 more
wiley   +1 more source

Implant‐related orofacial pain managed with implant apicoectomy: A case report

Clinical Advances in Periodontics, EarlyView.
Abstract Background In recent years, the use of implants has emerged as a widely accepted method for the replacement of missing teeth. Although rare, chronic pain associated with implant placement has been reported in the literature. Conversely, apicoectomy, the removal of the apical portion has been integrated into the implantology field in cases with
Oscar Durán‐Garnica, Karen Villarreal‐Arizpe, Hong Chen, Hsun‐Liang Chan, Guo‐Liang Cheng   +4 more
wiley   +1 more source

SLEEP APNEA IN ENDOCRINE DISORDERS

Alʹmanah Kliničeskoj Mediciny, 2016
In the recent years, an association between sleep apnea and a  number of endocrine diseases has been established. The secretion of many hormones after falling asleep is considerably changed, compared to the period of wakefulness.
I. V. Misnikova
doaj   +1 more source

Concomitant Transcatheter Edge‐to‐Edge Repair for Mitral and Tricuspid Regurgitation for Polyvalvular Disease

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT This patient is a 77‐year‐old male with non‐ischemic cardiomyopathy, severe tricuspid regurgitation, and moderate mitral regurgitation who underwent simultaneous transcatheter edge‐to‐edge repair of both mitral and tricuspid valves. Post‐procedure, the patient exhibited significant symptomatic improvement and reduced regurgitation severity ...
Omar Khan, Matthew Summers
wiley   +1 more source

Self-advising SVM for sleep apnea classification [PDF]

, 2012
In this paper Self-Advising SVM, a new proposed version of SVM, is investigated for sleep apnea classification. Self-Advising SVM tries to trans-fer more information from training phase to the test phase in compare to the traditional SVM.
Al-Jumaily, A, Laks, L, Maali, Y
core  

Variability in ACT Response to Standard UFH Bolus During PCI: A Prospective Study on Determinants of Subtherapeutic Anticoagulation

Catheterization and Cardiovascular Interventions, EarlyView.
ABSTRACT Background Unfractionated heparin (UFH) remains the standard anticoagulant during percutaneous coronary intervention (PCI), with guidelines recommending a target activated clotting time (ACT) of ≥250 s. However, despite receiving a standardized bolus dose, many patients fail to achieve this target.
Manh Cuong Vu, Antonin Trimaille, Amandine Granier, Adrien Carmona, Anis Elidrissi, Marion Kibler, Laurence Jesel, Patrick Ohlmann, Laurent Sattler, Olivier Morel   +9 more
wiley   +1 more source