Results 121 to 130 of about 1,591,227 (261)

Sleep‐Autonomic Interactions in Parkinson's Disease and Multiple System Atrophy: A Comparative Study Using Structural Equation Modeling

Movement Disorders Clinical Practice, EarlyView.
Abstract Background Parkinson's disease (PD) and multiple system atrophy (MSA) are α‐synucleinopathies with overlapping autonomic and sleep dysfunction, but distinct trajectories. Objectives This study compared sleep and autonomic profiles in PD and MSA and elucidated disease‐specific associations using structural equation modeling (SEM).
Bora Jin, Yoonkyung Lee, Seungho Lee, Byeol‐A Yoon, Young Jin Jeong, Sang‐Myung Cheon   +5 more
wiley   +1 more source

SURMOUNT‐REAL UK: A Pragmatic Randomized Clinical Trial to Assess the Effectiveness of Tirzepatide in Adults With Obesity

Obesity, EarlyView.
ABSTRACT Objective SURMOUNT‐REAL UK will evaluate the effectiveness of tirzepatide when offered in addition to standard‐of‐care (SoC) in adults with Class I obesity (BMI ≥ 30 and ≤ 34.9 kg/m2) and without diabetes in a UK primary care setting. Methods A 5‐year, phase 4, multicenter, open‐label, pragmatic randomized clinical trial is enabled through ...
Martin K. Rutter, Julie Mount, J. Martin Gibson, Joanne Webb, Cheryl Marler, Catherine Reed, Mugdha Gore, Wenyu Ye, Elisa Gomez Valderas, John Wilding, Naveed Sattar, Melanie J. Davies, Kamlesh Khunti, Richard Haynes, Rachel L. Batterham   +14 more
wiley   +1 more source

CHARGE Syndrome: What an Otolaryngologist Should Know—A Systematic Review and Meta‐Analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To synthesize the prevalence of otolaryngologic manifestations in CHARGE syndrome (CS) to support otolaryngologists in delivering comprehensive management. Data Sources PubMed/MEDLINE, Embase, and Google Scholar were searched for English‐ and French‐language studies published from January 1980 through January 2025.
Camille Caron, Massil Badji, Camille Prigent, Alix Pincivy, Erika Mercier, Mathieu Bergeron   +5 more
wiley   +1 more source

Pneumothorax as an İnitial Manifestation of Obstructive Sleep Apnea Syndrome

, 2010
Case report A sixty-five-year-old man with bullous lung disease was admitted to emergency service with chest pain and dyspnea that developed during sleep. Pneumothorax was diagnosed both clinically and radiologically.
Ceran, Sami, Suerdem, Mecit, Tülek, Baykal, Kanat, Fikret, Yosunkaya, Şebnem   +4 more
core   +1 more source

Comparative Meta‐Analysis of Complications of Maxillomandibular Advancement for OSA versus Orthognathic Surgeries for Dentofacial Deformities

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Maxillomandibular advancement (MMA) surgeries for obstructive sleep apnea (OSA) and orthognathic surgeries for dentofacial deformities (DFDs) are both complex procedures with distinct indications. This meta‐analysis and systematic review aimed to compare complications and recovery metrics between these surgeries. Data Sources CINAHL,
Mohamed Faisal Kassir, Angelica Walker, Lauren A. Howser, Allen Huang, Sami I. Nassar, Shaun A. Nguyen, Mohamed Abdelwahab   +6 more
wiley   +1 more source

Deciphering the Inflammatory Network in Pediatric Recurrent Tonsillitis: The Role of TRAF6, IRAK1, and miR‐146a‐5p

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To investigate the role of TNF receptor‐associated factor 6 (TRAF6), interleukin 1 receptor‐associated kinase 1 (IRAK1), and miR‐146a‐5p expression levels in the pathogenesis of recurrent tonsillitis. Study Design Case‐control study. Setting The study was conducted at the Department of Otorhinolaryngology, Muğla Training and Research
Ömer Faruk Güzel, Çilem Özdemir, Tuba Edgünlü, Ozan Gökdoğan   +3 more
wiley   +1 more source

Effects of Sleep Apnea on Nocturnal Free Fatty Acids in Subjects with Heart Failure

, 2011
Study Objectives: Sleep apnea is common in patients with congestive heart failure, and may contribute to the progression of underlying heart diseae. Cardiovascular and metabolic complications of sleep apnea have been attributed to intermittent hypoxia ...
Luciano F. Drager, SMITH, Philip L., DRAGER, Luciano F., BROWN, Cynthia D., JUN, Jonathan C., NAJJAR, Samer S., Vsevolod Y. Polotsky, SCHWARTZ, Alan R., Stephen S. Gottlieb, Philip L. Smith, POLOTSKY, Vsevolod Y., Alan R. Schwartz, Cynthia D. Brown, GOTTLIEB, Stephen S., Samer S. Najjar, Jonathan C. Jun   +15 more
core   +1 more source

Drug‐Induced Sleep Endoscopy Findings in Obese Adolescents With Sleep Apnea

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective Data regarding drug‐induced sleep endoscopy (DISE) findings in obese adolescents with obstructive sleep apnea (OSA) are lacking; such information could be used to direct and improve management as there is controversy whether adenotonsillectomy (AT) or positive airway pressure is standard therapy for this population.
Timothy Kearney, Turaj Vazifedan, Cristina M. Baldassari   +2 more
wiley   +1 more source

Post‐tonsillectomy Respiratory Complications in Children With Obesity: Systematic Review and Meta‐analysis

Otolaryngology–Head and Neck Surgery, EarlyView.
Abstract Objective To quantify and compare the risk of respiratory complications between children with and without obesity after tonsillectomy (with or without adenoidectomy). Data Sources Ovid MEDLINE, Embase, CINAHL, and Clarivate Web of Science. Review Methods Studies that reported post‐tonsillectomy respiratory complications in patients <18 years ...
Erin M. Kirkham, Nikhila Raol, Sharmi C. Amin, Bo Hyun Kong, Aayush Sharma, Ahab Chopra, Mark P. MacEachern, Prasanth Pattisapu   +7 more
wiley   +1 more source

Causal Relationship Between Childhood Obesity and Sleep Apnea Syndrome: Bidirectional Two-Sample Mendelian Randomization Analysis

Nature and Science of Sleep
Ping Wang,* Shuli Liu,* Ling Min Kong, Nannan Qi Department of Pediatrics, The Second Affiliated Hospital of Shandong First Medical University, Taian, Shandong, 271000, People’s Republic of China*These authors contributed equally to this ...
Wang P, Liu S, Kong LM, Qi N
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