Results 291 to 300 of about 907,577 (363)

Reshaping study design for faster extrapolation‐based drug approval in pediatric inflammatory bowel diseases: An ESPGHAN–NASPGHAN position paper

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Children with inflammatory bowel diseases (IBD) have limited access to the available advanced therapies, given the lengthy gap between adult and pediatric approval. We aimed to review key hurdles for pediatric trials and recommend practical solutions.
Dan Turner, Amit Assa, Mikkel Malham, Shira Yuval Bar‐Asher, Carla Rayan, Jeffrey S. Hyams, Holm H. Uhlig, Brad Pasternak, David C. Wilson, Hilary K. Michel, Lissy de Ridder, Eric Zuckerman, Marina Aloi, Peter Szitanyi, Marla C. Dubinsky, Anne M. Griffiths, Roberto Saldana, Javier Martín‐de‐Carpi, Eytan Wine, Richard K. Russell, Jeremy Adler, Joseph Picoraro   +21 more
wiley   +1 more source

Examining the Effects of Sleep Deprivation on Decision-Making: A Scoping Review. [PDF]

Behav Sci (Basel)
Agyapong-Opoku F, Agyapong-Opoku N, Agyapong B.   +2 more
europepmc   +1 more source

What is the impact of having a child dependent on home parenteral nutrition? A qualitative study in mothers and fathers

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Chronic intestinal failure (CIF) is a rare and complex disease, requiring home parenteral nutrition (HPN) to sustain growth and development. The impact on parents taking care for children with HPN remains underexplored. This qualitative study aimed to elucidate the experiences and challenges faced by parents in caring for HPN ...
Aysenur Demirok, Hedy A. van Oers, Marc A. Benninga, Lotte Haverman, Merit M. Tabbers   +4 more
wiley   +1 more source

Sex- and estrous-specific effects of paradoxical sleep deprivation: neurobehavioral changes and hippocampal neuroinflammation. [PDF]

Front Sleep
Olsen LK, Jones KA, Moore RJ, McCubbins H, Curtner FS, Sharma B, Hatcher-Solis CN.   +6 more
europepmc   +1 more source

Implications of sleep loss or sleep deprivation on muscle strength: a systematic review. [PDF]

Sleep Breath
Easow J, Bommasamudram T, Munnilari M, Adhikari R, Edwards BJ, Nayak KR, Vaishali K, Ravindrakumar A, Gallagher C, Pullinger SA.   +9 more
europepmc   +1 more source

Chrysanthemum morifolium extract protects HT22 cells from oxidative stress and enhances sleep via GABAergic modulation: contribution of luteolin‐7‐glucoside

Journal of the Science of Food and Agriculture, EarlyView.
Abstract BACKGROUND Chrysanthemum morifolium has long been utilized in traditional medicine for its antioxidant and sedative properties, yet its potential in sleep regulation and neuroprotection against oxidative stress remains underexplored. This study investigates the antioxidant and sleep‐enhancing effects of C.
Hyeongyeong Kim, Seok Hyun Chung, Singeun Kim, Sooil Ko, Jae‐Chul Jung, Hyun Jung Lee, Hyowon Lee   +6 more
wiley   +1 more source

Fear/Anxiety and Sleep Deprivation Combine to Predict Courage. [PDF]

Behav Sci (Basel)
Gibbons JA, McManus BE, White EC, Gibbons AM.   +3 more
europepmc   +1 more source

Understanding and improving the mental health of refugees and asylum‐seekers: Reflections from the closing panel of the 2024 International Society for Traumatic Stress Studies Annual Meeting

Journal of Traumatic Stress, EarlyView.
Abstract Forcible displacement due to war and persecution has reached unprecedented heights across the globe. The mental health impact of trauma and displacement on refugee communities is profound. Although there are several evidence‐based therapies that are efficacious in reducing symptoms of posttraumatic stress disorder and depression in refugees ...
Angela Nickerson, B. Heidi Ellis, Naser Morina, Frank Neuner, Lori Zoellner   +4 more
wiley   +1 more source

Health‐Related Quality of Life in Stevens‐Johnson Syndrome and Toxic Epidermal Necrolysis: A Qualitative Study

JEADV Clinical Practice, EarlyView.
ABSTRACT Background Epidermal necrolysis (EN), including Stevens‐Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN), are severe cutaneous drug reactions with high morbidity. However, the quality of life (QoL) impact during acute hospitalization is not well understood.
Jacob McFeeters, Allison Yan, Cole Veliky, Matthew Gallardo, Kelsey Nusbaum, Rachel Kirven, Kristopher Fisher, Abraham Korman, Hyoshin Kim, Benjamin H. Kaffenberger   +9 more
wiley   +1 more source