Results 21 to 30 of about 1,708,343 (195)

Genetics of Sleep and Sleep Disorders [PDF]

Cell, 2011
Sleep remains one of the least understood phenomena in biology--even its role in synaptic plasticity remains debatable. Since sleep was recognized to be regulated genetically, intense research has launched on two fronts: the development of model organisms for deciphering the molecular mechanisms of sleep and attempts to identify genetic underpinnings ...
Sehgal, Amita, Mignot, Emmanuel
openaire   +2 more sources

NLRP3 Deficiency Protects Against Intermittent Hypoxia-Induced Neuroinflammation and Mitochondrial ROS by Promoting the PINK1-Parkin Pathway of Mitophagy in a Murine Model of Sleep Apnea

Frontiers in Immunology, 2021
Obstructive sleep apnea (OSA) associated neurocognitive impairment is mainly caused by chronic intermittent hypoxia (CIH)-triggered neuroinflammation and oxidative stress. Previous study has demonstrated that mitochondrial reactive oxygen species (mtROS)
Xu Wu, Xu Wu, Linjing Gong, Liang Xie, Liang Xie, Wenyu Gu, Xinyuan Wang, Zilong Liu, Zilong Liu, Shanqun Li, Shanqun Li   +10 more
doaj   +1 more source

Latent Changes in Perceived Quality of Sleep Related to the COVID-19 Quarantine Measures in Italian University Students: Understanding the Role of Personality and Internalizing Symptoms

Mediterranean Journal of Clinical Psychology, 2020
The present online retrospective study aimed at evaluating the perceived sleep quality before the start of the lockdown measures and during the lockdown in a sample of Italian university students (N = 307).
Antonella Somma, Sara Marelli, Giulia Gialdi, Alessandra Castelnuovo, Samantha Mombelli, Luigi Ferini-Strambi, Andrea Fossati   +6 more
doaj   +1 more source

Digital CBTI hubs as a treatment augmentation strategy in military clinics: study protocol for a pragmatic randomized clinical trial

Trials, 2023
Background Chronic insomnia is the most prevalent sleep disorder among military service members, and it compromises readiness, performance, and physical and mental health. Cognitive behavioral treatment for insomnia (CBTI) is the standard of care for the
Anne Germain, Megan Wolfson, Matthew S. Brock, Brian O’Reilly, Hunter Hearn, Shelley Knowles, Vincent Mysliwiec, Meredith L. Wallace   +7 more
doaj   +1 more source

Executive Functioning and Personality Traits in Insomnia Disorder: A Preliminary Report on the Clinical Importance of Objective and Subjective Reduction of Total Sleep Time

Mediterranean Journal of Clinical Psychology, 2020
To confirm and extend previous findings on the relationships between executive functioning (EF) and insomnia, as well as the available evidence on the associations between personality traits and insomnia, 30 consecutively-admitted insomnia participants ...
Antonella Somma, Sara Marelli, Margherita Barranca, Giulia Gialdi, Chiara Lucini, Alessandra Castelnuovo, Samantha Mombelli, Luigi Ferini-Strambi, Andrea Fossati   +8 more
doaj   +1 more source

The optimal dose of Ramelteon for the better treatment adherence of delayed sleep–wake phase disorder: a dropout rate study

Frontiers in Neurology, 2023
BackgroundEvidence regarding the effectiveness of melatonin receptor agonists in treating delayed sleep–wake phase disorder (DSWPD) remains limited. This study aimed to determine the optimal dose of ramelteon, a melatonin receptor agonist, for the better
Shunsuke Takagi, Shunsuke Takagi, Shunsuke Takagi, Shunsuke Takagi, Genichi Sugihara, Hidehiko Takahashi, Hidehiko Takahashi, Yuichi Inoue, Yuichi Inoue   +8 more
doaj   +1 more source

Genetics of sleep and sleep disorders [PDF]

Cellular and Molecular Life Sciences, 2007
Genetic factors affect sleep. Studies in twin pairs demonstrate that the strong hereditary influences on sleep architecture and some sleep disorders are transmitted through families. Evidence like this strongly suggests that sleep regulation receives significant influence from genetic factors.
Kimura, M., Winkelmann, J.
openaire   +3 more sources

Polymorphisms in the circadian expressed genes PER3 and ARNTL2 are associated with diurnal preference and GNβ3 with sleep measures [PDF]

, 2014
Sleep and circadian rhythms are intrinsically linked, with several sleep traits, including sleep timing and duration, influenced by both sleep homeostasis and the circadian phase.
Lester, Kathryn, Lester, KJ, Archer, Simon, Archer, SN, Gregory, Alice M, Lester, Kathryn J., Barclay, Nicola L., Gregory, Alice, Nolan, Patrick M., Nolan, PM, Nolan, Patrick, Parsons, Michael J., Eley, Thalia C, Archer, Simon N., Barclay, Nicola, Gregory, AM, Patrick M Nolan (11641339), Barclay, Nicola L, Eley, Thalia C., Nolan, Patrick M, Archer, Simon N, Parsons, Michael J, Kathryn Lester (4462210), Nicola L Barclay (16221641), Parsons, Michael, Thalia C Eley (13615696), Parsons, MJ, Eley, Thalia, Simon N Archer (16221644), Alice M Gregory (11992776), Lester, Kathryn J, Michael J Parsons (16221638), Gregory, Alice M., Eley, TC, Barclay, NL   +34 more
core   +1 more source

The relationship between sleep and memory in PTSD [PDF]

, 2009
Includes abstract.Includes bibliographical references (leaves 117-127).Previous research has shown that in normal individuals sleep is critical to the formation of memories.
Lipinska, Malgorzata
core   +1 more source

Modified STOP-Bang for predicting perioperative adverse events in the Thai population

BMC Anesthesiology, 2021
Background Undiagnosed obstructive sleep apnea (OSA) is associated with adverse perioperative outcomes. The STOP-Bang questionnaire is a validated screening tool for OSA. However, its precision may vary among different populations.
Lisa Sangkum, Chama Wathanavaha, Visasiri Tantrakul, Munthana Pothong, Cherdkiat Karnjanarachata   +4 more
doaj   +1 more source