Results 41 to 50 of about 617,872 (307)

Age‐Related Characteristics of SYT1‐Associated Neurodevelopmental Disorder

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives We describe the clinical manifestations and developmental abilities of individuals with SYT1‐associated neurodevelopmental disorder (Baker‐Gordon syndrome) from infancy to adulthood. We further describe the neuroradiological and electrophysiological characteristics of the condition at different ages, and explore the associations ...
Sam G. Norwitz, Josefine Eck, Joel S. Winston, Kate Baker   +3 more
wiley   +1 more source

Circadian clock dysregulation: a potential mechanism of depression in obstructive sleep apnea patients

Translational Psychiatry
Obstructive sleep apnea (OSA) is characterized by co-occurrence with affective disorders. Our study aims to investigate the association of circadian clock gene expressions, and the presence and severity of depressive symptoms in OSA patients.
Agata Gabryelska, Szymon Turkiewicz, Piotr Kaczmarski, Adrian Gajewski, Piotr Białasiewicz, Dominik Strzelecki, Maciej Chałubiński, Marcin Sochal   +7 more
doaj   +1 more source

Sleep Stage Classification by a Combination of Actigraphic and Heart Rate Signals

Journal of Low Power Electronics and Applications, 2017
Although heart rate variability and actigraphic data have been used for sleep-wake or sleep stage classifications, there are few studies on the combined use of them. Recent wearable sensors, however, equip both pulse wave and actigraphic sensors.
Emi Yuda, Yutaka Yoshida, Ryujiro Sasanabe, Haruhito Tanaka, Toshiaki Shiomi, Junichiro Hayano   +5 more
doaj   +1 more source

Glymphatic Dysfunction Reflects Post‐Concussion Symptoms: Changes Within 1 Month and After 3 Months

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mild traumatic brain injury (mTBI) may alter glymphatic function; however, its progression and variability remain obscure. This study examined glymphatic function following mTBI within 1 month and after 3 months post‐injury to determine whether variations in glymphatic function are associated with post‐traumatic symptom severity ...
Eunkyung Kim, Han Gil Seo, Roh‐Eul Yoo, Byung‐Mo Oh   +3 more
wiley   +1 more source

Assessment of continuous positive airway pressure effect on the circadian clock signaling pathway in obstructive sleep apnea patients

Scientific Reports
Obstructive sleep apnea (OSA) is associated with circadian rhythm dysregulation plausibly through affecting clock genes. The study’s purpose was to investigate the effect of one-night continuous positive airway pressure treatment (CPAP treatment) on ...
Agata Gabryelska, Szymon Turkiewicz, Adrian Gajewski, Julia Jaromirska, Dominik Strzelecki, Piotr Białasiewicz, Maciej Chałubiński, Marcin Sochal   +7 more
doaj   +1 more source

Lessons Learned From a Delayed‐Start Trial of Modafinil for Freezing of Gait in Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Freezing of gait (FOG) in people with Parkinson's disease (PwPD) is debilitating and has limited treatments. Modafinil modulates beta/gamma band activity in the pedunculopontine nucleus (PPN), like PPN deep brain stimulation. We therefore tested the hypothesis that Modafinil would improve FOG in PwPD.
Tuhin Virmani, Lakshmi Pillai, Reid D. Landes, Aliyah Glover, Shannon Doerhoff, Jennifer Kleiner, Mitesh Lotia, Rohit Dhall, Edgar Garcia‐Rill   +8 more
wiley   +1 more source

Exploring differences in signaling pathways of the circadian clock and neuromodulators in obstructive sleep apnea

Scientific Reports
Obstructive sleep apnea (OSA) is a prevalent disorder characterized by recurring upper airway obstructions, leading to disrupted sleep and systemic complications. The complexity of OSA suggests intricate interactions between neuromodulators and circadian
Szymon Turkiewicz, Marcin Sochal, Marta Ditmer, Adrian Gajewski, Dominik Strzelecki, Piotr Białasiewicz, Maciej Chałubiński, Agata Gabryelska   +7 more
doaj   +1 more source

Brief Psychoeducational and Cognitive Therapy for Nightmare Disorder (BPCT-ND)

Sleep Science
In adults, nightmare disorder is related to sleep deprivation, drug consumption or abuse, or other comorbid sleep disorders such as insomnia or insufficient sleep syndrome.
Horacio Balam Álvarez-García, Ulises Jiménez-Correa   +1 more
doaj   +1 more source

Vestibular Evoked Myogenic Potentials Are Abnormal in Idiopathic REM Sleep Behavior Disorder

Frontiers in Neurology, 2018
Objectives: To investigate brainstem function in idiopathic REM sleep Behavior Disorder (iRBD), a condition occurring as a result of a derangement of connections within brainstem structures, with a battery of Vestibular Evoked Myogenic Potentials (VEMPs),
Edoardo Rosario de Natale, Francesca Ginatempo, Ilaria Laccu, Michela Figorilli, Andrea Manca, Beniamina Mercante, Monica Puligheddu, Franca Deriu   +7 more
doaj   +1 more source

Prevalence of sleep disorder diagnoses and sleep medication prescriptions in individuals with ADHD across the lifespan: a Swedish nationwide register-based study

BMJ Mental Health, 2023
Background Consistent evidence suggests a strong association between attention-deficit/hyperactivity disorder (ADHD) and subjectively reported sleep problems. However, the prevalence of clinically ascertained sleep disorder diagnoses and sleep medication
Catherine Hill, Henrik Larsson, Paul Lichtenstein, Samuele Cortese, Brian M D'Onofrio, Ebba Du Rietz, Miguel Garcia-Argibay, Rickard Ahlberg, Marc Taylor, Agniezska Butwicka   +9 more
doaj   +1 more source