Results 291 to 300 of about 73,127 (334)
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ACS Chemical Neuroscience, 2018
Glutamate, a primary excitatory neurotransmitter and an important intermediate in the cellular metabolism of the brain, has a widespread influence in the sleep-wake regulatory system. Glutamate transporters, including vesicular glutamate transporters and
Suifen He, Xiuping Zhang, Shaogang Qu
semanticscholar +1 more source
Glutamate, a primary excitatory neurotransmitter and an important intermediate in the cellular metabolism of the brain, has a widespread influence in the sleep-wake regulatory system. Glutamate transporters, including vesicular glutamate transporters and
Suifen He, Xiuping Zhang, Shaogang Qu
semanticscholar +1 more source
Circadian Rhythm Sleep Disorders
Chest, 2006Humans exhibit endogenous circadian rhythms that are regulated by the master circadian clock of the body, the suprachiasmatic nucleus. These endogenous circadian rhythms are aligned to the outside world by social and environmental cues. Circadian rhythm sleep disorders (CRSD) occur when there is an alteration of the internal timing mechanism or a ...
Phyllis C. Zee, Brandon Lu
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Disorders of sleep and circadian rhythms
2018Sleep is fundamental to the survival of humans. However, knowledge regarding the role of sleep and its regulation is poorly understood. Genetics in flies, mice, and humans has led to a detailed understanding of some aspects of circadian regulation. Sleep homeostasis (the effect of increasing periods of wakefulness on our sleep propensity) is largely ...
Ying-Hui Fu +3 more
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Circadian rhythms and disorders of the timing of sleep
The Lancet, 2022The daily alternation between sleep and wakefulness is one of the most dominant features of our lives and is a manifestation of the intrinsic 24 h rhythmicity underlying almost every aspect of our physiology. Circadian rhythms are generated by networks of molecular oscillators in the brain and peripheral tissues that interact with environmental and ...
Meyer, Nicholas +3 more
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Sleep and circadian rhythm disorders
2020This chapter reviews the most common sleep disorders in older adults and their treatment. It begins with a brief review of sleep physiology and then gives an outline on how to take a comprehensive sleep history. There are physiological sleep changes related to ageing, but sleep disorders are not part of normal ageing and are often associated with ...
Kirstie Anderson +3 more
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Circadian rhythm sleep disorders
Current Treatment Options in Neurology, 1999Delayed sleep phase syndrome (DSPS) is best treated by first using behaviorally scheduled sleeping and arising times to realign the patient's sleep-wake cycle to local time and then by keeping the cycle in synchrony with local time by adherence to a strict daily schedule. Adjunct treatment with morning light exposure or evening melatonin may be useful,
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Circadian Rhythm Sleep-Wake Disorders
Psychiatric Clinics of North America, 2015The circadian system regulates the timing and expression of nearly all biological processes, most notably, the sleep-wake cycle, and disruption of this system can result in adverse effects on both physical and mental health. The circadian rhythm sleep-wake disorders (CRSWDs) consist of 5 disorders that are due primarily to pathology of the circadian ...
Phyllis C. Zee +2 more
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Bipolar Disorders, 2020
Recent studies have suggested that evening blue light exposure is associated with sleep and circadian rhythm abnormalities. This study examined the effect of blue‐blocking (BB) glasses on sleep and circadian rhythm in patients with bipolar disorder (BD).
Yuichi Esaki +5 more
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Recent studies have suggested that evening blue light exposure is associated with sleep and circadian rhythm abnormalities. This study examined the effect of blue‐blocking (BB) glasses on sleep and circadian rhythm in patients with bipolar disorder (BD).
Yuichi Esaki +5 more
semanticscholar +1 more source
Journal of Clinical Psychiatry, 2017
OBJECTIVE Circadian rhythm dysfunction has been considered to be common in bipolar disorder (BD) and plays an important role in mood dysregulation in this disorder.
Y. Takaesu +6 more
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OBJECTIVE Circadian rhythm dysfunction has been considered to be common in bipolar disorder (BD) and plays an important role in mood dysregulation in this disorder.
Y. Takaesu +6 more
semanticscholar +1 more source
Neurobiology of circadian rhythm sleep disorders
Current Neurology and Neuroscience Reports, 2006To adapt to a 24-hour environment, nearly all organisms, from mammals to single-celled organisms, have developed endogenous mechanisms that generate nearly 24-hour (circadian) rhythms in physiology and behavior, the most notable being that of the daily cycles of sleep and wake.
Prasanth Manthena, Phyllis C. Zee
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