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Circadian Rhythm Sleep-Wake Disorders
, 2019Genetic analyses have revealed a missense mutation in a casein kinase ( CK1ε ) binding region of a Period gene ( hPer2 ), culminating in hypophosphorylation by CK1ε in vitro.
Virginia T. Boshes
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Circadian Rhythm Sleep Disorders and Phototherapy
Psychiatric Clinics of North America, 2006Circadian rhythm sleep disorders are characterized by a desynchronization between the timing of the intrinsic circadian clock and the extrinsic light-dark and social/activity cycles resulting in symptoms of excessive sleepiness and insomnia. This article explores the six recognized circadian rhythm sleep disorders: delayed sleep phase syndrome ...
Christopher D. Fahey, Phyllis C. Zee
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Circadian Rhythm Sleep Disorders
2018Children with developmental disabilities experience a high degree of sleep disturbance. Insomnia symptoms are the most commonly reported problems, though circadian rhythm sleep-wake disorders may also be common. There is significant overlap between insomnia symptoms and several symptoms associated with circadian rhythm sleep-wake disorders (CRSWDs ...
Emma Baker, Amanda L. Richdale
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Circadian Rhythm Sleep-Wake Disorders
CONTINUUM: Lifelong Learning in Neurology, 2023ABSTRACT OBJECTIVE This article provides an overview of advances in the understanding of circadian rhythms and the health implications of circadian disruption. LATEST DEVELOPMENTS Circadian medicine is a relatively new concept, with widespread overlap with many other areas
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Precision medicine in circadian rhythm sleep-wake disorders: current state and future perspectives.
Personalized Medicine, 2017In circadian rhythm sleep-wake disorders precision medicine is less developed than in other medical disciplines mainly because homeostatic sleep and circadian timing have a very complex phenotype with multiple genetic regulation mechanisms.
Henry Keijzer +6 more
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Cognition in circadian rhythm sleep disorders
2011Circadian rhythms in physiology and behavior exist in all living organisms, from cells to humans. The most evident rhythms are the recurrent cycles of sleep and wake as well as changes in alertness and cognitive performance across the 24h. Clearly, sleep pressure can exert a strong influence on cognitive performance, but the influence of circadian ...
Lori L. McGee-Koch +2 more
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Circadian rhythm sleep disorders (CRSD)
Sleep Medicine Reviews, 2002Circadian Rhythm Sleep Disorders (CRSD) are a group of sleep disorders characterized by a malsynchronization between a person's biological clock and the environmental 24-h schedule. These disorders can lead to harmful psychological and functional difficulties and are often misdiagnosed and incorrectly treated due to the fact that doctors are unaware of
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Sleep and circadian rhythm disorders in fibromyalgia
Current Rheumatology Reports, 2000Fibromyalgia (FM) is a syndrome of generalized muscle pain that is also associated with equally distressing symptoms of sleep disturbance and fatigue. FM shows clinical overlap with other stress-associated disorders, including chronic fatigue syndrome (CFS) and depression.
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Circadian rhythm sleep disorders
2003The grouping of circadian rhythm sleep disorders dates back to the Diagnostic Classification of Sleep Disorders in 1979 [4], based on a shared cardinal feature: all these disorders represent one form or another of initial misalignment between the patient’s sleep and wake behaviours and that which is desired or regarded as the societal norm.
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Sleep and circadian rhythms in bipolar disorders
2016Multiple lines of evidence support the conceptualization of bipolar disorder (BD) as a disorder of circadian rhythms, linking the disease with an abnormal internal timing (Harvey, 2008; McClung, 2013). Altered rhythmicity of circadian functions before and during mood episodes of illness, both mania and depression, has long been demonstrated.
Dallaspezia S., Benedetti F.
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