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Genetics of Sleep and Sleep Disorders [PDF]
Sleep remains one of the least understood phenomena in biology--even its role in synaptic plasticity remains debatable. Since sleep was recognized to be regulated genetically, intense research has launched on two fronts: the development of model organisms for deciphering the molecular mechanisms of sleep and attempts to identify genetic underpinnings ...
Emmanuel Mignot, Amita Sehgal
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Genetics of sleep and sleep disorders [PDF]
Genetic factors affect sleep. Studies in twin pairs demonstrate that the strong hereditary influences on sleep architecture and some sleep disorders are transmitted through families. Evidence like this strongly suggests that sleep regulation receives significant influence from genetic factors.
Juliane Winkelmann, M. Kimura
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Age-related changes in circadian regulation of the human plasma lipidome
Aging alters the amplitude and phase of centrally regulated circadian rhythms. Here we evaluate whether peripheral circadian rhythmicity in the plasma lipidome is altered by aging through retrospective lipidomics analysis on plasma samples collected in ...
Shadab A. Rahman+11 more
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Dissociative symptoms and sleep parameters: an all-night polysomnography study in patients with insomnia [PDF]
BackgroundDissociative disorders encompass a range of symptoms varying from severe absent-mindedness and memory problems to confusion about one's own identity. Recent studies suggest that these symptoms may be the by-products of a labile sleep–wake cycle.
De Volder, Ilse+7 more
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Effect of Atypical Antipsychotic Medications on the Risk of Obstructive Sleep Apnea in Individuals With Schizophrenia [PDF]
Background and Objective Weight gain and obesity could be side effects of taking atypical antipsychotic medications. They are major risk factors for obstructive sleep apnea.
Habibolah Khazaie+5 more
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Objectives Consumer-grade smart devices are now commonly used by the public to measure waking activity and sleep. However, the ability of these devices to accurately measure sleep in clinical populations warrants more examination.
Hailey Meaklim+5 more
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Sleep Disorders and Genes [PDF]
Versão preprintThe sleep-wake cycle is a neurobiological phenomenon that shows intervals of activity alternating with restfulness that appears with a periodicity approximating the 24h day-night cycle.
Amici+101 more
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Classification of Sleep Disorders [PDF]
The classification of sleep disorders is essential both for correct diagnosis and for coding purposes. There are three major sleep disorder classifications in the USA: the American Psychiatric Association’s Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-V), the American Academy of Sleep Medicine’s International Classification
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Sleep-amount differentially affects fear-processing neural circuitry in pediatric anxiety: A preliminary fMRI investigation. [PDF]
Insufficient sleep, as well as the incidence of anxiety disorders, both peak during adolescence. While both conditions present perturbations in fear-processing-related neurocircuitry, it is unknown whether these neurofunctional alterations directly link ...
Carlisi, Christina O+3 more
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