Results 41 to 50 of about 367,206 (264)

Five‐Year Disease Progression in Synuclein Seeding Positive Sporadic Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective To provide a comprehensive description of disease progression in synuclein seeding assay (SAA) positive sporadic Parkinson Disease participants, using Neuronal Synuclein Disease integrated biological and functional impairment staging framework.
Paulina Gonzalez‐Latapi, Caroline Gochanour, Seung Ho Choi, Hyunkeun Cho, Chelsea Caspell‐Garcia, Christopher Coffey, Michael Brumm, David‐Erick Lafontant, Yuge Xiao, Thomas Tropea, John Seibyl, Caroline Tanner, Charles S. Venuto, Karl Kieburtz, Lana M. Chahine, Kathleen L. Poston, Andrew Siderowf, Kenneth Marek, Tanya Simuni, The Parkinson's Progression Markers Initiative   +19 more
wiley   +1 more source

Impact of type D personality on bilevel positive airway pressure compliance and side-effects in sleep apnoea patients

ERJ Open Research
Background Type D personality, characterised by social inhibition and negative affectivity, has been linked to lower compliance with continuous positive airway pressure (CPAP) and mandibular advancement device treatment, and increased side-effects in ...
Frederik Veys, An-Marie Schyvens, Ilse De Volder, Ann Van Gastel, Marijke Dieltjens, Anneclaire V. Vroegop, Olivier M. Vanderveken, Johan Verbraecken   +7 more
doaj   +1 more source

The relationship between neurotrophins and cognitive functions in the context of emotional response to sleep deprivation

European Psychiatry
Introduction Studies conducted up to date on the subject of deprivation of sleep (DS) primarily focused either on its impact on certain cognitive abilities or mood-enhancing effects in patients with depression.
M. Ditmer, A. Binienda, A. Tarasiuk, A. Gabryelska, P. Białasiewicz, S. Turkiewicz, F. F. Karuga, J. Fichna, M. Sochal   +8 more
doaj   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Better sleep quality and higher physical activity levels predict lower emotion dysregulation among persons with major depression disorder

BMC Psychology, 2023
Background People with Major Depression Disorders (MDD) often complain about sleep problems and experience emotion dysregulation. Prior research suggests physical activity can improve both sleep quality and emotional control.
Leeba Rezaie, Ebrahim Norouzi, Alexandra J. Bratty, Habibolah Khazaie   +3 more
doaj   +1 more source

Posterior Cortical Atrophy in the Asia‐Pacific: A Report From the PCA Asian Workgroup

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Posterior Cortical Atrophy (PCA) is a distinct dementia syndrome primarily affecting spatial abilities and visual processing. It is associated with degeneration in the posterior part of the brain. PCA is subclassified into PCA‐pure and PCA‐plus syndromes based on consensus criteria.
Yuttachai Likitjaroen, Ya‐Ting Chang, Levinia Lim, Pai‐Yi Chiu, Jung‐Lung Hsu, SangYun Kim, Wataru Narita, Na Young Ryoo, Kyoko Suzuki, Nagaendran Kandiah, Sebastian Crutch, Ming‐Chyi Pai   +11 more
wiley   +1 more source

Commonalities and Differences in NREM Parasomnias and Sleep-Related Epilepsy: Is There a Continuum Between the Two Conditions?

Frontiers in Neurology, 2020
Introduction: Differential diagnosis between disorders of arousal (DoA) and sleep-related hypermotor epilepsy (SHE) often represents a clinical challenge.
Carlotta Mutti, Giorgia Bernabè, Noemi Barozzi, Rosario Ciliento, Irene Trippi, Giuseppe Pedrazzi, Nicoletta Azzi, Liborio Parrino   +7 more
doaj   +1 more source

CSF Monoamine Metabolites and Cognitive Trajectory in Early Parkinson's Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background Imaging and postmortem studies indicate that abnormalities in monoaminergic neurotransmission contribute to cognitive impairment in Parkinson's disease (PD). However, it remains uncertain if cerebrospinal fluid (CSF) monoamine metabolites can serve as biomarkers of cognitive decline in early PD.
Jing‐Yu Shao, Rong Li, Yu‐Xiang Jiao, Kai Ma, Hong‐Qi Yang, Zheng‐Yu Sun, Jie‐Wen Zhang, Shuai Chen   +7 more
wiley   +1 more source

The effect of sleep and its restriction on selected inflammatory parameters

Scientific Reports
Insufficient sleep duration may lead to a series of immune dysfunctions. One of the factors influencing this effect could be physical activity (PA). The study aimed to assess the impact of deprivation of sleep (DS) on selected inflammatory parameters ...
Marcin Sochal, Marta Ditmer, Szymon Turkiewicz, Filip Franciszek Karuga, Piotr Białasiewicz, Agata Gabryelska   +5 more
doaj   +1 more source

Irregular sleep/wake patterns are associated with poorer academic performance and delayed circadian and sleep/wake timing

Scientific Reports, 2017
The association of irregular sleep schedules with circadian timing and academic performance has not been systematically examined. We studied 61 undergraduates for 30 days using sleep diaries, and quantified sleep regularity using a novel metric, the ...
Andrew J. K. Phillips, William M. Clerx, Conor S. O’Brien, Akane Sano, Laura K. Barger, Rosalind W. Picard, Steven W. Lockley, Elizabeth B. Klerman, Charles A. Czeisler   +8 more
doaj   +1 more source