Results 51 to 60 of about 404,286 (313)

Shedding light on neurofilament involvement in cognitive decline in obstructive sleep apnea and its possible role as a biomarker

Frontiers in Psychiatry, 2023
Obstructive sleep apnea is one of the most common sleep disorders with a high estimated global prevalence and a large number of associated comorbidities in general as well as specific neuropsychiatric complications such as cognitive impairment.
Julia Jaromirska, Piotr Kaczmarski, Dominik Strzelecki, Marcin Sochal, Piotr Białasiewicz, Agata Gabryelska   +5 more
doaj   +1 more source

Functional and Structural Evidence of Neurofluid Circuit Aberrations in Huntington Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Disrupted neurofluid regulation may contribute to neurodegeneration in Huntington disease (HD). Because neurofluid pathways influence waste clearance, inflammation, and the distribution of central nervous system (CNS)–delivered therapeutics, understanding their dysfunction is increasingly important as targeted treatments emerge.
Kilian Hett, Abigail Dubois, Melanie Leguizamon, Alexander Song, Paula Trujillo, Colin D. McKnight, Ciaran M. Considine, Manus J. Donahue, Daniel O. Claassen   +8 more
wiley   +1 more source

Sleep Architecture in Night Shift Workers Police Officers with Obstructive Sleep Apnea-hypopnea Syndrome [PDF]

Sleep Science
Introduction: Reduced sleep to increase work hours is common among police officers, when this situation is combined with Obstructive sleep apnea/hypopnea syndrome (OSAHS), health consequences are greater, therefore we believe there is a
Selene Verde-Tinoco, Rafael Santana-Miranda, Romel Gutiérrez-Escobar, Reyes Haro, Joana Miranda-Ortiz, Talia Berruga-Fernandez, Ulises Jimenez-Correa, Adrián Poblano   +7 more
doaj   +1 more source

Baseline Regional Cholinergic Denervation Predicts Cognitive Trajectories in Moderate Parkinson Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive decline is a disabling and variable feature of Parkinson disease (PD). While cholinergic system degeneration is linked to cognitive impairments in PD, most prior research reported cross‐sectional associations. We aimed to fill this gap by investigating whether baseline regional cerebral vesicular acetylcholine transporter ...
Taylor Brown, Giulia Carli, Prabesh Kanel, Stiven Roytman, Jaimie Barr, Nicolaas I. Bohnen, Roger L. Albin   +6 more
wiley   +1 more source

A collaborative approach to managing sleep problems [PDF]

, 2015
In response to the local need for advice and support for parents of children and young people with learning disabilities, a structured 3 week sleep clinic was developed by a community team who targeted a small group of parents and carers and provided ...
McAdam, Nicola, Butterfield, Vicky, Miller, Sheena   +2 more
core   +1 more source

Developmental and Epileptic Encephalopathy due to Biallelic Pathogenic Variants in PIGM

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective PIGM encodes a critical enzyme in the glycosylphosphatidylinositol (GPI)‐anchor biosynthesis pathway. While promoter‐region mutations in PIGM have been associated with a relatively mild phenotype characterized by portal vein thrombosis and absence seizures, recent evidence suggests that coding‐region mutations result in a more severe
Júlia Sala‐Coromina, Anna Marcé‐Grau, Barbara Masotto, Marta Codina, Lamia BenJemaa, Yasmina Elaribi, Mónica Martinez‐Gallo, Roger Colobran, Angel Sanchez‐Montañez, Irene Valenzuela, Yoshiko Murakami, Alfons Macaya   +11 more
wiley   +1 more source

Impact of type D personality on bilevel positive airway pressure compliance and side-effects in sleep apnoea patients

ERJ Open Research
Background Type D personality, characterised by social inhibition and negative affectivity, has been linked to lower compliance with continuous positive airway pressure (CPAP) and mandibular advancement device treatment, and increased side-effects in ...
Frederik Veys, An-Marie Schyvens, Ilse De Volder, Ann Van Gastel, Marijke Dieltjens, Anneclaire V. Vroegop, Olivier M. Vanderveken, Johan Verbraecken   +7 more
doaj   +1 more source

Better sleep quality and higher physical activity levels predict lower emotion dysregulation among persons with major depression disorder

BMC Psychology, 2023
Background People with Major Depression Disorders (MDD) often complain about sleep problems and experience emotion dysregulation. Prior research suggests physical activity can improve both sleep quality and emotional control.
Leeba Rezaie, Ebrahim Norouzi, Alexandra J. Bratty, Habibolah Khazaie   +3 more
doaj   +1 more source

Epilepsy‐Associated Variants of a Single SCN1A Codon Exhibit Divergent Functional Properties

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Pathogenic variants in SCN1A, which encodes the voltage‐gated sodium channel NaV1.1, are associated with multiple epilepsy syndromes exhibiting a range of clinical severity. SCN1A variants are reported in different syndromes, including Dravet syndrome, which is associated with loss‐of‐function, whereas neonatal/infantile‐onset ...
Lanie N. Liebovitz, Christopher H. Thompson, Linda C. Laux, Alfred L. George Jr.   +3 more
wiley   +1 more source

The relationship between neurotrophins and cognitive functions in the context of emotional response to sleep deprivation

European Psychiatry
Introduction Studies conducted up to date on the subject of deprivation of sleep (DS) primarily focused either on its impact on certain cognitive abilities or mood-enhancing effects in patients with depression.
M. Ditmer, A. Binienda, A. Tarasiuk, A. Gabryelska, P. Białasiewicz, S. Turkiewicz, F. F. Karuga, J. Fichna, M. Sochal   +8 more
doaj   +1 more source