Results 51 to 60 of about 2,341,236 (258)

Sleep efficiency and event−related potentials in patients with depression: the mediating role of serum C-reactive protein

Frontiers in Psychiatry
BackgroundPatients with major depressive disorder (MDD) may experience cognitive dysfunction and sleep disorders. Limited research exists on the neurophysiological mechanisms that connect sleep efficiency and cognitive function in individuals with MDD ...
Liang Fang, Liang Fang, Liang Fang, Peng Wang, Tianqin Xie, Tianqin Xie, Tianqin Xie, Shuai Ding, Shuai Ding, Shuai Ding, Ting Wang, Ting Wang, Ting Wang, Jiajia Zhang, Jiajia Zhang, Jiajia Zhang, Aiguo Zhang, Aiguo Zhang, Aiguo Zhang, Peng Zhu, Daomin Zhu, Daomin Zhu, Daomin Zhu   +22 more
doaj   +1 more source

The ubiquitin system in normal and infected germinal center B cells

FEBS Letters, EarlyView.
The ubiquitin system plays a central role in germinal center (GC) B cells, influencing differentiation to long‐lived memory B cells. Oncogenic gammaherpesviruses gain access to memory B cells by establishing latency in GC B cells. Mapping ubiquitin mechanisms in normal and infected GC B cells will define specific molecular circuits in B cells germane ...
Destiny Davis, Lesly Mejia, Emily K Moser   +2 more
wiley   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Efficacy and safety of exogenous melatonin for secondary sleep disorders and sleep disorders accompanying sleep restriction: meta-analysis. [PDF]

, 2006
Objective To conduct a systematic review of the efficacy and safety of exogenous melatonin in managing secondary sleep disorders and sleep disorders accompanying sleep restriction, such as jet lag and shiftwork disorder.
Hartling, L., Tjosvold, L., Buscemi, N.., Baker, G., Vohra, S., Pandya, R., Klassen, T. P., Hooton, N., Vandermeer, B.   +8 more
core   +1 more source

A First Case of Compulsive Amnestic Sleep-Related Shopping Induced by Pramipexole Therapy of Restless Legs Syndrome

Sleep Science
Dopamine receptor agonists (DAs) such as pramipexole/ropinirole are recognized treatments for restless legs syndrome (RLS) and Parkinson's disease (PD).
Michael Todd, Carlos H. Schenck, Erin Golden, Ranji Varghese   +3 more
doaj   +1 more source

Cognitive behavioral therapy for insomnia helps to reverse cognitive impairment in insomnia patients [PDF]

Sleep Science
Introduction: Insomnia is the most common of sleep disorders, it induces a wide variety of organic symptoms, including somatic and cognitive impairments.
Daniela Deyanira Guarneros Roniger, Yoaly Arana Lechuga, Enrique Esqueda León, Rosa Obdulia González Robles, Óscar Sánchez Escandón, Guadalupe Jovanna Terán Pérez, Javier Velázquez Moctezuma   +6 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

Aging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

White Matter Hyperintensity Burden and Short‐Interval Change Associated With Sleep Apnoea in the UK Biobank

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Background and Purpose White matter hyperintensities (WMH) are a core neuroimaging marker of cerebral small vessel disease (CSVD). Sleep apnoea (SA) is a recognized vascular risk factor, but its associations with regional WMH burden, short‐interval WMH change and cognitive performance in population‐based cohorts remain incompletely defined. We
Peng Cheng, Diego Z. Carvalho, Shahid Karim, Anwar Chahal, Virend K. Somers   +4 more
wiley   +1 more source

Circadian lipid and hepatic protein rhythms shift with a phase response curve different than melatonin

Nature Communications, 2022
A key property of circadian rhythms is that they can be reset in response to environmental time cues; this response is described by a Phase Response Curve (PRC).
Brianne A. Kent, Shadab A. Rahman, Melissa A. St. Hilaire, Leilah K. Grant, Melanie Rüger, Charles A. Czeisler, Steven W. Lockley   +6 more
doaj   +1 more source

A Two‐Stage Questionnaire and Actigraphy Screening for iRBD in a Multicenter Retrospective Cohort

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Isolated rapid‐eye‐movement sleep behavior disorder is a prodromal marker of synucleinopathies. However, most cases remain undiagnosed due to the insufficient predictive value of questionnaires and limited access to confirmatory video‐polysomnography. We assessed a two‐stage screening strategy combining a brief questionnaire on rapid‐
Caleb A. Massimi, Giorgio Ricciardiello Mejia, Andre Metzger, Kang Hyun Ryu, Salonee Marwaha, Eva Grzegorczyk, Li Zhou, Eliana Jacobs, Boris Gilyadov, Claudia Kunney, Liqhwa Ncube, Ankit Parekh, Emmanuel Mignot, Fanny M. Elahi, Joseph Winer, Kathleen Poston, Andreas Brink‐Kjaer, Emmanuel H. During   +17 more
wiley   +1 more source