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Prader-Willi syndrome (PWS) is the most prevalent syndromic form of obesity, which starts during early childhood in the setting of hyperphagia. Due to the development of obesity, there is a high prevalence of obstructive sleep apnea (OSA) among these ...
Nauras Hwig +4 more
doaj +1 more source
Hematopoietic (stem) cells—The elixir of life?
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo +4 more
wiley +1 more source
Background To investigate factors associated with obstructive sleep apnea (OSA) in young, non-obese (body mass index [BMI]
Rafeek Kandy +8 more
doaj +1 more source
BackgroundPatients with major depressive disorder (MDD) may experience cognitive dysfunction and sleep disorders. Limited research exists on the neurophysiological mechanisms that connect sleep efficiency and cognitive function in individuals with MDD ...
Liang Fang +22 more
doaj +1 more source
Cognitive behavioral therapy for insomnia helps to reverse cognitive impairment in insomnia patients [PDF]
Introduction: Insomnia is the most common of sleep disorders, it induces a wide variety of organic symptoms, including somatic and cognitive impairments.
Daniela Deyanira Guarneros Roniger +6 more
doaj +1 more source
Molecular bases of circadian magnesium rhythms across eukaryotes
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley +1 more source
Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley +1 more source
Polysomnographic Findings in A Late Onset Wilson’s Disease Patient [PDF]
Scientific BACKGROUND: Wilson’s disease (WD) is an autosomal recessive degenerative disorder of copper metabolism. As a degenerative disease affecting many parts of CNS, WD has the potential to disrupt sleep regulatory mechanisms and to cause sleep
Barış Metin +3 more
doaj
A key property of circadian rhythms is that they can be reset in response to environmental time cues; this response is described by a Phase Response Curve (PRC).
Brianne A. Kent +6 more
doaj +1 more source
Obstructive sleep apnea is one of the most common sleep disorders with a high estimated global prevalence and a large number of associated comorbidities in general as well as specific neuropsychiatric complications such as cognitive impairment.
Julia Jaromirska +5 more
doaj +1 more source

