Results 181 to 190 of about 23,814 (204)

Timing is everything: Expert opinion on researching epilepsy rhythms by the ILAE Task Force on Chronobiology

Epilepsia, EarlyView.
Abstract Recurrent seizures, the hallmark of epilepsy, are influenced by rhythms operating over multiple timescales. Chronobiology is the study of biological timing that aims to explain temporal patterns of events like seizures. Fueled by recent advances in genetics, computational modeling, and device engineering, the chronobiology of epilepsy is now a
Maxime O. Baud, Christophe Bernard, Birgit Frauscher, Philippa J. Karoly, Vikram R. Rao   +4 more
wiley   +1 more source

Adolescent Insomnia Disorder - Problematic Internet Use Nexus: A Convergent Developmental Trajectory - Bridging Neuroimaging Biomarkers, Molecular Susceptibility, and Environmental-Neurocognitive Cascades. [PDF]

Psychol Res Behav Manag
Zeng Z, Jiang J, Wang M, Huang Y, Maes M, Li J.   +5 more
europepmc   +1 more source

Baseline characteristics and feasibility of clinical outcome measures in CDKL5 deficiency disorder: The CANDID observational study

Epilepsia, EarlyView.
Abstract Objective CDKL5 deficiency disorder (CDD) is a rare X‐linked developmental and epileptic encephalopathy caused by loss‐of‐function variants in the CDKL5 gene. Preclinical experiments using enzyme replacement or gene therapies show promise and could be transformative therapies.
Xavier Liogier d'Ardhuy, CANDID Partners, Tricia Cimms, Kristina Lindsten, Marco Rizzo, Alison Skrinar, Peter St. Wecker, Ana Mingorance, Orrin Devinsky   +8 more
wiley   +1 more source

Type-specific effects of orofacial pain on sleep quality: a cross-sectional clinical study. [PDF]

J Oral Facial Pain Headache
Coşgun-Baybars S, Talu MH, Yalçin H, Gökdemir D.   +3 more
europepmc   +1 more source

Rhythms in longitudinal thalamic recordings are linked to seizure risk

Epilepsia, EarlyView.
Abstract Objective Seizure unpredictability remains a major clinical challenge for people with epilepsy. Previous works have shown that seizure risk is associated with circadian and multi‐day cycles in both brain and physiological signals. However, it remains unclear whether neural activity from deep brain structures such as the anterior nucleus of the
Xinbing Zhang, Zachary T. Sanger, Thomas Lisko, Steffen Ventz, Robert A. McGovern, Theoden I. Netoff   +5 more
wiley   +1 more source

The efficacy and safety of acupuncture for Parkinson's disease insomnia: a systematic review and meta-analysis. [PDF]

Front Neurol
Gu Y, Liang Y, Han H, Yin H, Zheng Z.
europepmc   +1 more source

Bidirectional sleep‐seizure interactions and orexin in a mouse model of tuberous sclerosis complex‐related epilepsy

Epilepsia, EarlyView.
Abstract Objective A strong bidirectional relationship exists between epilepsy and sleep, with seizures often occurring more frequently in sleep and, in turn, sleep being disrupted by seizures. However, the mechanistic basis of seizure–sleep interactions is poorly understood.
Nicholas R. Rensing, Lirong Han, Dongjun Guo, Thomas J. Foutz, Michael Wong   +4 more
wiley   +1 more source

Drug-Induced Psychosis: A Drastic Turn After a Kidney Transplant. [PDF]

Cureus
Obaid DA, AlJasmi M, Alawadhi KY, Sahu S.   +3 more
europepmc   +1 more source

Evolution of the European Medicines Agency clinical guidelines for epilepsy drug development between 2010 and 2025: A comparative analysis by the ILAE Task Force on Regulatory Affairs

Epilepsia, EarlyView.
Abstract Objective The latest European Medicines Agency (EMA) guideline on the clinical investigation of medicines to treat epileptic disorders was adopted by the EMA Committee for Medicinal Products for Human Use in 2025. We compared this guideline with the previous version (2010), highlighting areas where significant revisions were introduced ...
Stéphane Auvin, Alexis Arzimanoglou, Jacqueline French, Kelly G. Knupp, Lieven Lagae, Eugen Trinka, Dennis Dlugos, Emilio Perucca   +7 more
wiley   +1 more source

Glycemic Control, Quality Of Life, And Social Determinants Of Sleep Quality In Newly Diagnosed Type 2 Diabetes Mellitus. [PDF]

Clin Neuropsychiatry
Bay NQ, Mai Phuong DT, Hiep PH, Hanh LM, Anh Khoa PT, Thuy Hanh NT, Vung ND, Tuan VM, Thanh Thuy TT, Tuan LA, Thanh NH.   +10 more
europepmc   +1 more source