Differentiated effects of the multimodal antidepressant vortioxetine on sleep architecture: Part 1, a pharmacokinetic/pharmacodynamic comparison with paroxetine in healthy men [PDF]
We compared the effect of vortioxetine, paroxetine and placebo after three days of dosing on sleep architecture. This was a randomised, double-blind, four-way crossover, placebo-controlled, multiple-dose study in 24 healthy young men.
Areberg, J +4 more
core +1 more source
Alzheimer's disease and sleep disturbances: a review [PDF]
The association between Alzheimer's disease (AD) and sleep disturbances has received increasing scientific attention in the last decades. However, little is known about the impact of sleep and its disturbances on the development of preclinical AD stages,
Conrado Regis Borges +4 more
doaj +1 more source
Can Improving Postoperative Sleep Speed Up Surgical Recovery?
Sleep disturbance is common during recovery after surgical procedures and may have an important effect on mortality, and quality of life. Sleep restriction/deprivation, including decreased quantity and continuity, is common in patients who are patients ...
Flavia Rodrigues da Silva +5 more
doaj +1 more source
Insomnia has been linked to adverse chronic obstructive pulmonary disease (COPD) outcomes including exacerbations, yet its impact on COPD-related healthcare utilization and costs is unknown.
Faith S. Luyster +2 more
doaj +1 more source
Objective To investigate the sleep structure and autonomic nervous function of patients with chronic insomnia combined with obstructive sleep apnea (OSA) and analyze their correlation with neuropsychological characteristics.
WAN Ya⁃hui +5 more
doaj +1 more source
Managing toxicities associated with immune checkpoint inhibitors: consensus recommendations from the Society for Immunotherapy of Cancer (SITC) Toxicity Management Working Group. [PDF]
Cancer immunotherapy has transformed the treatment of cancer. However, increasing use of immune-based therapies, including the widely used class of agents known as immune checkpoint inhibitors, has exposed a discrete group of immune-related adverse ...
Abdallah, K. +80 more
core +2 more sources
Yoga for generalized anxiety disorder: design of a randomized controlled clinical trial. [PDF]
Generalized anxiety disorder (GAD) is a common disorder associated with significant distress and interference. Although cognitive behavioral therapy (CBT) has been shown to be the most effective form of psychotherapy, few patients receive or have access ...
Bui, Eric +7 more
core +1 more source
Management of rapid eye movement sleep behavior disorder in patients with Parkinson's disease [PDF]
Among all of the devastating effects that Parkinson’s disease (PD) has on an individual, sleep dysfunction is one that can have a profound effect on the entire family of the patient. The most potentially destructive of these sleep syndromes being that of
Jeffries, Michael
core +1 more source
EEG–fMRI of idiopathic and secondarily generalized epilepsies [PDF]
We used simultaneous EEG and functional MRI (EEG–fMRI) to study generalized spike wave activity (GSW) in idiopathic and secondary generalized epilepsy (SGE).
Duncan, J.S. +7 more
core +1 more source

