Results 61 to 70 of about 2,670,505 (246)

A Flexible‐Substrate 5‐µm‐Diameter Needle Electrode: Minimizing Neuronal Death and Enabling Year‐Long Neural Recording

Advanced Materials Interfaces, EarlyView.
An electrophysiological recording technology that uses a 5‐µm‐diameter microneedle electrode device is presented. Due to the remarkable small dimension of the microneedle, the electrode provides minimal invasive neural recording in a mouse brain and enables long‐term recording exceeding the year‐long duration.
Hinata Sasaki, Koji Yamashita, Sayaki Shimizu, Kensei Sakamoto, Rika Numano, Kowa Koida, Takeshi Kawano   +6 more
wiley   +1 more source

Chemical AI in the Limelight: The Contribution of Photochromic Materials and Oscillatory Chemical Reactions

Advanced Optical Materials, EarlyView.
Photochromic compounds are versatile ingredients for the development of Chemical AI. When they are embedded in a tight microenvironment, they become Markov blankets. They are also valuable for processing Boolean and Fuzzy logic. They contribute to neuromorphic engineering in wetware based on opto‐chemical signals exchanged with oscillatory chemical ...
Pier Luigi Gentili
wiley   +1 more source

In vitro and in vivo evaluation of nano-based films for buccal delivery of zolpidem

Brazilian Oral Research
Insomnia is becoming increasingly prevalent in the world general population. Therapies used by patients include over-the-counter therapies, herbal and dietary supplements, and pharmacological or nonpharmacological treatments.
Bandar Essa AL-DHUBIAB
doaj   +1 more source

Attention-based Learning for Sleep Apnea and Limb Movement Detection using Wi-Fi CSI Signals [PDF]

arXiv, 2023
Wi-Fi channel state information (CSI) has become a promising solution for non-invasive breathing and body motion monitoring during sleep. Sleep disorders of apnea and periodic limb movement disorder (PLMD) are often unconscious and fatal. The existing researches detect abnormal sleep disorders in impractically controlled environments.
arxiv  

Optical Microfiber Biomedical Sensors: Classification, Applications, and Future Perspectives

Advanced Sensor Research, EarlyView.
This review delves deeply into the various types of optical microfiber biosensors, grounded firmly in their fundamental principles, and underscores their indispensable roles in pushing forward biomedical advancements. It examines the latest advancements, challenges faced by these biosensors in practical applications, future directions, breakthroughs ...
Lili Liang, Fei Xie, Li Jin, Bowen Yang, Li‐Peng Sun, Bai‐Ou Guan   +5 more
wiley   +1 more source

Critical periods and Autism Spectrum Disorders, a role for sleep [PDF]

arXiv, 2022
Brain development relies on both experience and genetically defined programs. Time windows where certain brain circuits are particularly receptive to external stimuli, resulting in heightened plasticity, are referred to as critical periods. Sleep is thought to be essential for normal brain development.
arxiv  

Bilirubin Targeting WNK1 to Alleviate NLRP3‐Mediated Neuroinflammation

Advanced Science, EarlyView.
At physiological concentrations, bilirubin binds to the kinase domain of WNK1, thereby augmenting its activity and facilitating the phosphorylation of downstream SPAK/OSR1. This phosphorylation inhibits KCC2 activity, leading to elevate intracellular chloride levels in neurons.
Linfei Mao, Jiayu Lu, Quanjun Yang, Zhenqi Liu, Cuiping Wu, Bingbing Ke, Kaiyan Su, Haolin Yuan, Yaqi Cui, Yao Wang, Richard Salvi, Guang Yang, Shankai Yin, Feng Liu, Chunyan Li   +14 more
wiley   +1 more source

α‐Synuclein Pathology Spreads in a Midbrain–Hindbrain Assembloid Model

Advanced Science, EarlyView.
A novel midbrain–hindbrain assembloid model demonstrates the spread of α‐synuclein pathology, a hallmark of Parkinson's disease, mimicking Braak's hypothesis. This model reveals how pathology propagates from the hindbrain to the midbrain, inducing synaptic changes and early signs of neuronal vulnerability. It offers an innovative platform for exploring
Gemma Gomez‐Giro, Daniela Frangenberg, Daniela Vega, Alise Zagare, Kyriaki Barmpa, Paul M. A. Antony, Graham Robertson, Rahman Sabahi‐Kaviani, Kristian Haendler, Nathalie Kruse, Florentia Papastefanaki, Rebecca Matsas, Malte Spielman, Regina Luttge, Jens C. Schwamborn   +14 more
wiley   +1 more source

Clinical application of antidepressants in the treatment of insomnia symptoms

Chinese Journal of Contemporary Neurology and Neurosurgery, 2013
Insomnia is one of the common complaints among all clinical departments. In recent years, some studies have demonstrated that insomnia symptoms can be improved or treated by some antidepressants.
Iok-man WONG, Qiao-ting HUANG, Ji-yan PAN   +2 more
doaj  

Sleep state misperception: is there a CNS structural source? [PDF]

Sleep Science
Introduction: We describe a case of sleep state misperception in a patient with a neurotoxoplasmosis lesion in the left nucleocapsular region. Case report: A 40-year-old female patient presented relating sleeplessness over the past 2 years ...
Giselle de Martin Truzzi, Igor de Lima Teixeira, Lucila Bizari Fernandes do Prado, Gilmar Fernandes do Prado, Sergio Tufik, Fernando Morgadinho Coelho   +5 more
doaj   +1 more source