Results 131 to 140 of about 155,892 (263)

FUCA2 Sustains AKT Signaling and Suppresses Senescence by Antagonizing FUT3‐Mediated ErbB3 Fucosylation in Lung Adenocarcinoma

Advanced Science, EarlyView.
ABSTRACT While targeted therapies have improved outcomes in lung adenocarcinoma (LUAD), many patients still lack targetable mutations. Here, we identified alpha‐L‐fucosidase 2 (FUCA2) as a crucial driver of LUAD by preventing cellular senescence. Mechanistically, through the restriction of fucosyltransferase 3 (FUT3)‐mediated α‐1,3‐fucosylation of ...
Lu Chen, Jintao Guo, Fei Li, Mingjie Gao, Runyang Li, Zhaozhang Huang, Yaolin Zheng, Chunyi Gao, Jihuan Hou, Qiang Yu, Bowen Zheng, Xuemei Chen, Wenqing Zhang, Xiaoting Hong, Yali Zheng, Daxuan Wang, Qiyuan Li, Tianhui Hu, Yan‐yan Zhan   +18 more
wiley   +1 more source

Daily changes in sleep stages and associated cardiovascular parameters during pregnancy: using a wearable device. [PDF]

Front Glob Womens Health
Guo Y, Xu Q, Narvaez L, Dutt N, Kehoe P, Qu A.   +5 more
europepmc   +1 more source

Synchronization‐Dissipation in the Cardiorespiratory System

Advanced Science, EarlyView.
By modeling central nervous coupling and viscoelastic interactions in the cardiorespiratory system we show that synchronization produces a 10% gain in cardiac efficiency in humans. It is surmised that respiratory sinus arrhythmia improves cardiac pumping efficiency by reducing dynamic stress and power dissipation in the pulmonary vasculature.
Joshua R. Border, Alain Nogaret, Andrew Lefevre, Vishal Jain   +3 more
wiley   +1 more source

Exploring cardiac autonomic dysfunction in synucleinopathies with parkinsonism through awake-sleep stages: a possible connection to cardiovascular death. [PDF]

BMJ Neurol Open
Limotai N, Somboon T, Suanprasert N, Rujirussawarawong S, Tumnark T, Unwanatham N, Limotai C.   +6 more
europepmc   +1 more source

A two-branch trade-off neural network for balanced scoring sleep stages on multiple cohorts. [PDF]

Front Neurosci, 2023
Zhang D, Sun J, She Y, Cui Y, Zeng X, Lu L, Tang C, Xu N, Chen B, Qin W.   +9 more
europepmc   +1 more source

Multidimensional and Multifunctional Laser‐Induced Graphene (LIG) for Point‐of‐Care and Wearable Biosensing, Theranostics, and Bioactive Interfaces Toward Personalized Healthcare and Regenerative Medicine

Advanced Science, EarlyView.
Multidimensional laser‐induced graphene (LIG) spanning from 0D to 3D architectures is comprehensively reviewed for multifunctional biomedical platforms, including biosensing, theranostics, and bioactive interface applications, which highlights its potentials for point‐of‐care diagnostics, wearable health monitoring, smart drug delivery, and tissue ...
Li Zhang, Yurou Yuan, Xiaohong Ding, Wing Cheung Mak   +3 more
wiley   +1 more source

Time-series visual representations for sleep stages classification. [PDF]

PLoS One
Padovani Ederli R, Vega-Oliveros DA, Soriano-Vargas A, Rocha A, Dias Z.   +4 more
europepmc   +1 more source

A Holistic Strategy for Classification of Sleep Stages with EEG. [PDF]

Sensors (Basel), 2022
Prabhakar SK, Rajaguru H, Ryu S, Jeong IC, Won DO.   +4 more
europepmc   +1 more source

Inhibitory Decay and Supercritical Brain Dynamics During Sleep Deprivation

Advanced Science, EarlyView.
Sleep deprivation progressively shifts human brain dynamics from near‐critical toward supercritical states, as revealed by neuronal avalanche analysis of resting‐state fMRI. These changes track subjective sleep pressure rather than vigilance lapses and show marked network heterogeneity. A circuit model suggests that reduced inhibitory efficacy provides
Dai Zhang, Liqin Zhou, Rong Wang, Yuehua Han, Zhentao Zuo, Yanghua Tian, Ke Zhou   +6 more
wiley   +1 more source

Associations of sleep-associated variants with wearable-derived sleep stages in the All of Us research program. [PDF]

Sleep
Chan IN, Nouraie SM, Chan SY, Kelly NJ.
europepmc   +1 more source