Results 61 to 70 of about 47,163 (209)

Solving the Amyloid Paradox: Unveiling the Complex Pathogenicity of Amyloid Fibrils

Aggregate, EarlyView.
This review addresses the gap between strong evidence for the involvement of amyloid fibrils in neurodegeneration and the failure of anti‐amyloid therapies, a phenomenon herein termed the “amyloid paradox.” To address this paradox, we provide a comprehensive summary of the current understanding of fibrils' pathogenic properties and mechanisms ...
Maksim I. Sulatsky, Olesya V. Stepanenko, Olga V. Stepanenko, Anna I. Sulatskaya   +3 more
wiley   +1 more source

Advancements in Machine Learning for Microrobotics in Biomedicine

Advanced Intelligent Systems, EarlyView.
Microrobotics is an innovative technology with great potential for noninvasive medical interventions. However, controlling and imaging microrobots pose significant challenges in complex environments and in living organisms. This review explores how machine learning algorithms can address these issues, offering solutions for adaptive motion control and ...
Amar Salehi, Soleiman Hosseinpour, Nasrollah Tabatabaei, Mahmoud Soltani Firouz, Niloufar Zadebana, Richard Nauber, Mariana Medina‐Sánchez   +6 more
wiley   +1 more source

Sleep quality and the integrity of ascending reticular activating system – A multimodal MRI study

Heliyon
Sleep is crucial for maintaining brain homeostasis and individuals with insufficient sleep are prone to more pronounced brain atrophy as compared to sufficiently sleeping peers.
Viktória Kokošová, Lubomír Vojtíšek, Marek Baláž, Silvia Mangia, Shalom Michaeli, Pavel Filip   +5 more
doaj  

Artificial Intelligence‐Enhanced, Closed‐Loop Wearable Systems Toward Next‐Generation Diabetes Management

Advanced Intelligent Systems, EarlyView.
Recent advancements in wearable healthcare have brought accessible continuous glucose monitoring systems (CGMs) for diabetes management. To address the limitations of CGMs, closed‐loop systems utilizing monitored glucose levels for insulin dosing are being developed.
Wei Huang, Ivo Pang, Jing Bai, Binbin Cui, Xiaojuan Qi, Shiming Zhang   +5 more
wiley   +1 more source

Autonomous Navigation of Bio‐Intelligent Cyborg Insect Based on Insect Visual Perception

Advanced Intelligent Systems, EarlyView.
The bio‐intelligent cyborg insect (BCI) introduces a noninvasive ultraviolet‐based control method, leveraging natural sensory behaviors for adaptive navigation. By integrating biological and artificial intelligence, BCI minimizes habituation and enhances locomotion in complex environments.
Chowdhury Mohammad Masum Refat, Mochammad Ariyanto, Ryo Tanaka, Kotaro Yamamoto, Keisuke Morishima   +4 more
wiley   +1 more source

Feasibility, functionality, and user experience with wearable technologies for acute exacerbation monitoring in patients with severe COPD

Frontiers in Signal Processing
Background: The increasing interest in remote patient monitoring technologies in patients with chronic obstructive pulmonary disease (COPD) requires a phased and stepwise investigative approach, which includes high-risk clinical subgroups who stand to ...
Olivia C. Iorio, Felix-Antoine Coutu, Felix-Antoine Coutu, Dany Malaeb, Bryan A. Ross, Bryan A. Ross, Bryan A. Ross, Bryan A. Ross   +7 more
doaj   +1 more source

Standardization of Terminology, Definitions, and Outcome Criteria for Bleeding in Hereditary Hemorrhagic Telangiectasia: International Consensus Report

American Journal of Hematology, EarlyView.
ABSTRACT Hereditary hemorrhagic telangiectasia (HHT, Osler‐Weber‐Rendu disease) is the second most common inherited bleeding disorder worldwide, affecting approximately 1 in 5000 people. Development of disease‐modifying and efficacious hemostatic agents to treat HHT has finally begun after decades without such medical therapies.
Hanny Al‐Samkari, Raj S. Kasthuri, Hans‐Jurgen Mager, Jenny Y. Zhou, Marcelo M. Serra, Bethany T. Samuelson‐Bannow, Layla N. Van Doren, Jay F. Piccirillo, Marianne S. Clancy, Keith R. McCrae, Sonia M. Thomas, Antoni Riera‐Mestre, Allyson M. Pishko, Sarah Sewaralthahab, James R. Gossage, Vivek N. Iyer, Cedric Hermans, Adrienne Hammill, Ingrid Winship, Meir Mei‐Zahav, Annette von Drygalski, Scott Olitsky, Marie E. Faughnan   +22 more
wiley   +1 more source

Platform‐Mediated Gig Work and Health: A Scoping Review

American Journal of Industrial Medicine, EarlyView.
ABSTRACT Background We sought to assess the size, depth, and rigor of empirical literature on platform‐mediated gig work and health. Methods We conducted a scoping review of peer‐reviewed studies from January 1, 2000, through May 29, 2024, that examined platform‐mediated gig work and any measure of physical or mental health.
Claire E. Margerison, Grace E. Joachim, Tim R. Michling, Candice Y. Johnson   +3 more
wiley   +1 more source

Worth the Effort: Lessons for Discovery and Care From an Unusual Case of Gorlin Syndrome

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Gorlin‐Goltz Syndrome (GGS) is a rare autosomal dominant genetic disorder encompassing a diverse range of clinical manifestations, including congenital anomalies and predisposition to cancer. Pathogenic variants in PTCH1 and SUFU account for up to 79% and 6% of cases, respectively. Currently, an estimated 15%–27% of individuals with a clinical
V. Taliercio, J. Zhao, S. E. Boyden, R. Mao, P. Bayrak‐Toydemir, A. Pflaum, J. Palumbos, A. Andrews, E. E. Baldwin, C. Welt, Mackenzie Fait, Undiagnosed Diseases Network, L. D. Botto, D. Viskochil   +13 more
wiley   +1 more source

Resolving the Diagnostic Odyssey in Inherited Retinal Dystrophies Through Long‐Read Genome Sequencing

American Journal of Medical Genetics Part A, EarlyView.
ABSTRACT Inherited retinal dystrophies (IRDs) inherited are visually disabling monogenic diseases with remarkable genetic and phenotypic heterogeneity. Mutations in more than 300 different genes have been identified as disease‐causing. The genetic diagnosis of IRDs has significantly advanced with the integration of Next Generation Sequencing (NGS ...
Gerardo E. Fabian‐Morales, Vianey Ordoñez‐Labastida, William J. Rowell, Christine Lambert, Cairbre Fanslow, Alexander Robertson, Juan C. Zenteno   +6 more
wiley   +1 more source