Results 101 to 110 of about 61,963 (243)

A Research Classification for Long COVID: Symptom Frequency and Severity Improve Accuracy of Machine Learning Models

Chronic Diseases and Translational Medicine, EarlyView.
Leonard A. Jason, Lauren Ruesink, Jacob Furst, Ben Z. Katz   +3 more
wiley   +1 more source

The burden of the postictal state in epilepsy: A prospective, single‐center observational cohort study

Epileptic Disorders, EarlyView.
Abstract Objective The postictal state is a major yet underrecognized component of the epilepsy burden. We aimed to develop a structured patient‐reported instrument to quantify postictal recovery, characterize its multidimensional burden, and identify demographic, clinical, psychiatric, and treatment‐related factors associated with postictal severity ...
Ionuț‐Flavius Bratu, Agnès Trébuchon, Fabrice Bartolomei   +2 more
wiley   +1 more source

Prevalence and associated factors of circadian rhythm sleep-wake disorders and insomnia among visually impaired Japanese individuals. [PDF]

BMC Public Health, 2021
Tamura N, Sasai-Sakuma T, Morita Y, Okawa M, Inoue S, Inoue Y.   +5 more
europepmc   +1 more source

Use of artificial intelligence in magnetic resonance imaging across the epileptic patient's journey: A meta‐analysis of four clinical applications

Epilepsia, EarlyView.
Abstract Objective The application of artificial intelligence/machine learning (AI/ML) to magnetic resonance imaging (MRI) promises to enhance and support clinical decision‐making in epilepsy. However, there currently lacks an appropriate assessment of clinical utility and study rigor of current AI/ML‐driven models that are targeted toward supporting ...
Judy Chen, Ella Sahlas, Yigu Zhou, Natalie Chen, Jim Xie, Farhan Wadia, Lorenzo Caciagli, Aristides Hadjinicolaou, Alexander G. Weil, Roy W. Dudley, Dewi V. Schrader, Andrea Bernasconi, Neda Bernasconi, Boris C. Bernhardt   +13 more
wiley   +1 more source

Cognitive and behavioral clinical outcome assessments in children with developmental and epileptic encephalopathies: Issues and instruments

Epilepsia, EarlyView.
Abstract Children with developmental and epileptic encephalopathies (DEEs) face cognitive and behavioral challenges that may have a greater impact than seizures on their quality of life (QoL). The need to assess these nonseizure outcomes for evaluating treatments is increasingly recognized.
Cinzia Correale, Nicola Specchio, Jenny Downs, J. Helen Cross, Simona Cappelletti, Andrea Palacio‐Navarro, Sam Geuens, Kette Valente, Andreas Brunklaus, Colin Reilly   +9 more
wiley   +1 more source

Validation of sleep-wake estimation from thigh-worn accelerometers against polysomnography in adolescents with and without mental disorders

BMC Psychiatry
Background To validate the estimation of sleep-wake patterns using thigh-worn accelerometers against polysomnography —the gold standard for sleep assessment—in adolescents with and without mental disorders from the Danish High Risk and Resilience Study ...
Martin Wilms, Anne Søndergaard, Poul Jørgen Jennum, Peter J. Johansson, Pasan Hettiarachchi, Sinnika Birkehøj Rohd, Anette Faurskov Bundgaard, Andreas Faergemand Laursen, Marta Schiavon, Doris Helena Bjarnadóttir Streymá, Maja Gregersen, Mette Falkenberg Krantz, Lotte Veddum, Aja Neergaard Greve, Nicoline Hemager, Ole Mors, Anne Amalie Elgaard Thorup, Merete Nordentoft, Lone Baandrup   +18 more
doaj   +1 more source

Long‐term prognosis of pharmacotherapy in newly diagnosed focal epilepsy patients and the predictive value of baseline seizure timing: A prospective cohort study

Epilepsia, EarlyView.
Abstract Objective Epilepsy is a highly heterogeneous neurological disorder with significant prognostic variability. Accurate long‐term outcome prediction remains a clinical challenge. We investigated pharmacotherapeutic prognosis and key predictors, particularly baseline seizure timing, to guide individualized treatment.
Lei Sun, Shouye Sun, Xinyue Zhang, Weihong Lin   +3 more
wiley   +1 more source

Add‐on treatment with vinpocetine reduces seizure frequency and improves comorbidities in patients with loss‐of‐function γ‐aminobutyric acid type A receptor variants

Epilepsia, EarlyView.
Abstract Objective The semisynthetic compound vinpocetine has gained attention as a potential precision medicine for developmental and epileptic encephalopathies caused by loss‐of‐function (LoF) variants in γ‐aminobutyric acid type A (GABAA) receptor genes. As a positive allosteric modulator of GABAA receptors, case reports suggest that vinpocetine can
Cathrine E. Gjerulfsen, Vivian W. Y. Liao, Tomasz S. Mieszczanek, Anne V. Jakobsen, Elena Gardella, Kern Olofsson, Marina Nikanorova, Allan Bayat, Sebastian Ortiz, Sarah Weckhuysen, Cecilie Johannessen Landmark, Orrin Devinsky, Mary Chebib, Philip K. Ahring, Guido Rubboli, Rikke S. Møller   +15 more
wiley   +1 more source

Epileptic encephalopathy with spike‐and‐wave activation in sleep associated with Tatton–Brown–Rahman syndrome responsive to highly purified cannabidiol

Epileptic Disorders, EarlyView.
Anita N. Datta
wiley   +1 more source

Are comorbid sleep disorders associated with higher risk for sudden unexpected death in epilepsy? Observations from a Canadian epilepsy clinic

Epilepsia, EarlyView.
Abstract Objective Pooled mortality is nearly three times higher in people with epilepsy (PWE). Approximately 80% of sudden unexpected death in epilepsy (SUDEP) events occur during sleep, and primary sleep disorders are prevalent in the general population and PWE.
Marion Lazaj, Ellen Lee, Tristan Derry, Helen Driver, Gavin P. Winston, Lysa Boissé Lomax, Ana Johnson, Garima Shukla   +7 more
wiley   +1 more source