Investigation of causal effects of blood metabolites on insomnia and circadian rhythm sleep wake disorders. [PDF]
Lv Z +7 more
europepmc +1 more source
Absence seizures: Update on signaling mechanisms and networks
Abstract Absence seizures (AS) are a hallmark of genetic generalized epilepsies (GGE), characterized by brief episodes of impaired consciousness accompanied by electroencephalographic spike‐and‐wave discharges (SWDs). Traditionally attributed to cortico‐thalamo‐cortical (CTC) dysrhythmia, emerging evidence suggests a more intricate pathophysiological ...
Ozlem Akman, Filiz Onat
wiley +1 more source
Ming Qiao,1– 4,* Hui Zhang,1– 3,* Luhua Yuan,1– 3 Ying Huang,5 Qiuchi Zhang,1,6 Shengjie Pan,1,7 Limin Xu,1,8 Cong Fu,1– 3 Huan Yu1– 31Department of Neurology, Huashan Hospital, Fudan University, Shanghai, People’s Republic of China ...
Qiao M +8 more
doaj
Neonatal seizures: Advances in diagnosis and management
Abstract The International League Against Epilepsy (ILAE) created the ILAE Neonatal Task Force that classified neonatal seizures, defined neonatal epilepsy syndromes, and specified treatment guidelines. These frameworks, in addition to improved access to genetic testing and other recent advances, have revolutionized the diagnosis and management of ...
Elissa G. Yozawitz +2 more
wiley +1 more source
Visual analysis of the research frontiers, hotspots and trends of exercise therapy intervention in tumor-related sleep-wake disorders. [PDF]
Han J +9 more
europepmc +1 more source
Artificial intelligence in preclinical epilepsy research: Current state, potential, and challenges
Abstract Preclinical translational epilepsy research uses animal models to better understand the mechanisms underlying epilepsy and its comorbidities, as well as to analyze and develop potential treatments that may mitigate this neurological disorder and its associated conditions. Artificial intelligence (AI) has emerged as a transformative tool across
Jesús Servando Medel‐Matus +7 more
wiley +1 more source
Rest‐activity patterns across development in two mouse models of autism and epilepsy
Abstract Objective Sleep disturbances are common in individuals with autism spectrum disorder (ASD) and epilepsy and are increasingly recognized as comorbidities that affect disease severity and quality of life. This study investigated rest‐activity patterns across development in two genetic mouse models relevant to ASD and epilepsy: synapsin 2 (Syn2 ...
Ipsa Dash +4 more
wiley +1 more source
Disentangling the complex landscape of sleep-wake disorders with data-driven phenotyping: A study of the Bernese center. [PDF]
Aellen FM +5 more
europepmc +1 more source
Lack of association between PER3 variable number tandem repeat and circadian rhythm sleep-wake disorders. [PDF]
Hida A +7 more
europepmc +1 more source
Abstract Objective Neurodevelopmental disorders (NDDs) and epilepsy are often associated. Increasing evidence highlights a pivotal role for pathogenic variants in genes encoding synaptic scaffolding proteins. Within this group, TANC2 has recently been implicated in intellectual developmental disorder with autistic features and language delay, with or ...
Lorenzo Perilli +12 more
wiley +1 more source

