Results 211 to 220 of about 272,474 (340)

Molecular‐Informed Network Analysis Unveils Fatigue‐Related Functional Connectivity in Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Fatigue in Parkinson's disease (PD) is a prevalent and debilitating non‐motor symptom. Despite its significant impact on quality of life, the underlying neurochemical and network‐based mechanisms remain poorly understood. Objectives This observational study applied a multimodal imaging approach to explore potential links between the
Ilaria Antonella Di Vico, Manuela Moretto, Agnese Tamanti, Giovanni Tomelleri, Giulia Burati, Daniel Martins, Ottavia Dipasquale, Mattia Veronese, Alessandra Bertoldo, Elisa Menini, Angela Sandri, Sarah Ottaviani, Francesca Benedetta Pizzini, Michele Tinazzi, Marco Castellaro   +14 more
wiley   +1 more source

Microstructural Changes in the Tuberal Hypothalamus Correlate with Daytime Sleepiness in Lewy Body Disorders

Movement Disorders, EarlyView.
Abstract Background Excessive daytime sleepiness (EDS) is a disabling symptom of Lewy body disorders (LBD). The hypothalamus is a key sleep–wake regulator and is involved in Lewy pathology, but its contribution to EDS in LBD remains unclear. Objectives To use diffusion‐weighted magnetic resonance imaging (MRI) to detect hypothalamic microstructure and ...
Jesse S. Cohen, Hamsanandini Radhakrishnan, Christopher A. Olm, Sandhitsu R. Das, Philip A. Cook, David A. Wolk, Daniel Weintraub, David J. Irwin, Corey T. McMillan   +8 more
wiley   +1 more source

Molecular Tools to Study and Control Dopaminergic Neurotransmission With Light

Medicinal Research Reviews, EarlyView.
ABSTRACT Dopaminergic neurotransmission is involved in several important brain functions, such as motor control, learning, reward‐motivated behavior, and emotions. Dysfunctions of dopaminergic system may lead to the development of various neurological and psychiatric disorders, like Parkinson's disease, schizophrenia, depression, and addictions ...
Galyna Maleeva, Carlo Matera, Silvia Roda, Alessio Colleoni, Marco De Amici, Pau Gorostiza   +5 more
wiley   +1 more source

Positive Effects of Caffeine Therapy in a Girl with PDE2A‐Related Paroxysmal Dyskinesia

Movement Disorders Clinical Practice, EarlyView.
Katerina Bernardi, Moritz Thiel, Anne Koy   +2 more
wiley   +1 more source

A Focus on Natural Autophagy Modulators as Potential Host‐Directed Weapons Against Emerging and Re‐Emerging Viruses

Medicinal Research Reviews, EarlyView.
ABSTRACT Autophagy is a highly conserved intracellular process involved in maintaining homeostasis and in the degradation of damaged organelles and external pathogens. Nature provides complex and varied reservoirs of scaffolds and chemical entities that may have a pivotal role in the search for new therapeutic leads.
Ilaria Cursaro, Sara Rossi, Stefania Butini, Sandra Gemma, Gabriele Carullo, Giuseppe Campiani   +5 more
wiley   +1 more source

Nutraceutical Blends Promote Weight Loss, Inflammation Reduction, and Better Sleep: The Role of Faecalibacterium prausnitzii in Overweight Adults–A Double‐Blind Trial

Molecular Nutrition &Food Research, EarlyView.
This study explored how a 90‐day nutraceutical blend with prebiotics, minerals, and silymarin affects the gut‐brain axis in overweight adults. Results showed improved gut microbiota, reduced inflammation, and better sleep, mood, and quality of life, suggesting a strong link between gut health and mental well‐being.
Aline Boveto Santamarina, Victor Nehmi Filho, Jéssica Alves de Freitas, Lucas Augusto Moysés Franco, Roberta Cristina Martins, Joyce Vanessa Fonseca, José Antônio Orellana Turri, Mariana Tedesco Hufnagel, Daniel Pecoraro Demarque, Bruna Fernanda Rio Branco da Silva, Arianne Fagotti Gusmão, Eloísa Helena Ribeiro Olivieri, Erica de Souza, Esther Alves de Souza, José Pinhata Otoch, Ana Flávia Marçal Pessoa   +15 more
wiley   +1 more source

Interstitial Cystitis/Bladder Pain Syndrome in Men

Neurourology and Urodynamics, EarlyView.
ABSTRACT Aims In April 2025, the Wake Forest Institute for Regenerative Medicine hosted a Global Consensus meeting on interstitial cystitis/bladder pain syndrome (IC/BPS) in Winston‐Salem, NC. The goal of this meeting was to establish attainable targets in phenotyping, diagnosis, and biomarkers for IC/BPS.
Madeline Snipes, Wyatt Whitman, Michel Pontari, Jennifer Anger, Michael Samarinas, Rajesh Taneja   +5 more
wiley   +1 more source

The Genetic Regulation of Human Sleep-Wake Rhythms and Patterns [PDF]

, 2019
Archer, Benedetti, Borbély, Bozek, Brennan, Carpen, Carpen, Chong, Colten, Dijk, Dijk, Eckel-Mahan, Eide, Fisher, Fustin, Gamble, Garaulet, Gehrman, Gotter, Grimaldi, Haus, He, Heath, Hermida, Hirano, Hirano, Hirano, Hohjoh, Horne, Hsu, Jagannath, Johns, Jones, Jones, Kaasik, Keller, Kleitman, Kraus, Lee, Leung, Lewy, Luo, Mang, Mishima, Mohawk, Narasimamurthy, Patke, Pellegrino, Prather, Reischl, Roenneberg, Roenneberg, Rosbash, Sateia, Spoelstra, Toh, Vadnie, Vanselow, Veatch, Viola, Viola, Xing, Xu, Xu, Zhang, Zhang, Åkerstedt   +66 more
core   +1 more source

Treatment of Persistent Sleep-Wake Schedule Disorders in Adolescents with Methylcobalalmin (Vitamin B₁₂) [PDF]

, 1991
Takahisa Ohta, Kota Ando, Tetsu Iwata, Norio Ozaki, Yuhei Kayukawa, Minoru Terashima, Toshiya Okada, Y. Kasahara   +7 more
openalex   +1 more source

Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS) Diagnosis: Current Limitations and a Pragmatic Clinical Diagnostic Definition

Neurourology and Urodynamics, EarlyView.
ABSTRACT Objective To develop a consensus on diagnostic criteria for interstitial cystitis/bladder pain syndrome (IC/BPS). Materials and Methods A subcommittee was identified based on expertise in IC/BPS diagnostic criteria. An outline was generated and iteratively modified until it was found to be acceptable by subcommittee members as the basis for ...
Glenn T. Werneburg, Robert Moldwin, C. Lowell Parsons, M. Shivam Priyadarshi, Sanjay Sinha, J. Quentin Clemens   +5 more
wiley   +1 more source