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Disorders of Sleep and Wakefulness
Primary Care: Clinics in Office Practice, 1984This article provides information on the background and development of "sleep disorders medicine" and sleep disorders centers and a discussion of obstructive sleep apnea, narcolepsy, sleep-related periodic leg movements, and the use and misuse of hypnotic medication.
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British Journal of Hospital Medicine, 2006
Sleep disorders are very common. Prevalence estimates vary widely because of variable case definitions, but roughly 25% of adults have insomnia, 20% have troublesome snoring, and 3% have obstructive sleep apnoea syndrome (OSAS) – repetitive apnoea during sleep and daytime sleepiness. That is a lot of people: insomnia is about as common as hypertension,
L. G. Olson, A Ambrogetti
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Sleep disorders are very common. Prevalence estimates vary widely because of variable case definitions, but roughly 25% of adults have insomnia, 20% have troublesome snoring, and 3% have obstructive sleep apnoea syndrome (OSAS) – repetitive apnoea during sleep and daytime sleepiness. That is a lot of people: insomnia is about as common as hypertension,
L. G. Olson, A Ambrogetti
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Irregular Sleep-Wake Rhythm Disorder [PDF]
Sleep Medicine Clinics, 2015 Irregular sleep-wake rhythm disorder is a circadian rhythm disorder characterized by multiple bouts of sleep within a 24-hour period. Patients present with symptoms of insomnia, including difficulty either falling or staying asleep, and daytime excessive sleepiness.
Sabra M. Abbott, Phyllis C. Zee
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Pediatric Sleep-Wake Disorders
Neurologic Clinics, 2012Sleep-wake problems are common during childhood and adolescence. They are of diverse cause, and can contribute significantly to alterations in behavior, cognition, and learning. Obstructive sleep apnea, central hypoventilation syndrome, narcolepsy, periodic hypersomnia, delayed sleep phase syndrome, restless legs syndrome, parasomnias, and sleep ...
Suresh Kotagal, Amit Chopra
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Circadian Rhythm Sleep-Wake Disorders
, 2019Genetic analyses have revealed a missense mutation in a casein kinase ( CK1ε ) binding region of a Period gene ( hPer2 ), culminating in hypophosphorylation by CK1ε in vitro.
Virginia T. Boshes
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Precision medicine in circadian rhythm sleep-wake disorders: current state and future perspectives.
Personalized Medicine, 2017In circadian rhythm sleep-wake disorders precision medicine is less developed than in other medical disciplines mainly because homeostatic sleep and circadian timing have a very complex phenotype with multiple genetic regulation mechanisms.
Henry Keijzer +6 more
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Sleep-Wake Disorders in Childhood
CONTINUUM: Lifelong Learning in Neurology, 2020ABSTRACTPURPOSE OF REVIEWThe presentation of sleep issues in childhood differs from the presentation in adulthood and may be more subtle. Sleep issues may affect children differently than adults, and distinct treatment approaches are often used in children.RECENT FINDINGSSodium oxybate was approved by the US Food and Drug Administration (FDA) in ...
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Hypocretins (orexins) and sleep–wake disorders
The Lancet Neurology, 2005Since their discovery in 1998, the hypocretins (orexins)-peptides that are produced by a group of neurons situated in the posterolateral hypothalamus--have been shown to excite many CNS areas including many neuronal systems that regulate sleep and wakefulness.
Christian R. Baumann +1 more
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Disorders of Sleep and Wakefulness
1987Narcolepsy and sleep apnoea are the commonest causes of persistent daytime sleepiness. There are approximately 20 000 people with narcolepsy in the United Kingdom, 100 000 in the United States. The diagnosis of narcoleptic syndrome is established by the history of recurrent daily short sleep attacks in combination with cataplexy, brief episodes of loss
J. D. Parkes +3 more
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1997
Basic Sleep Research: Prostaglandins and Sleep O. Hayaishi. Modeling Sleep Propensity and Sleep Disturbances H. Schultz, et al. Circadian Rhythms: Movement, Mood, and Moment in Human Subjects During Temporal Isolation J. Aschoff. Feedback from Sleep-Wake Rhythm onto the Circadian Pacemaker in Humans K.-I. Honma, et al.
Masako Okawa, Karlheinz Meier-Ewert
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Basic Sleep Research: Prostaglandins and Sleep O. Hayaishi. Modeling Sleep Propensity and Sleep Disturbances H. Schultz, et al. Circadian Rhythms: Movement, Mood, and Moment in Human Subjects During Temporal Isolation J. Aschoff. Feedback from Sleep-Wake Rhythm onto the Circadian Pacemaker in Humans K.-I. Honma, et al.
Masako Okawa, Karlheinz Meier-Ewert
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