Lipofuscin: The Missing Link in the Worsening of Obstructive Sleep Apnea
Lipofuscin, also known as the age pigment, is a permanent autofluorescent intracellular deposit that accumulates with aging or oxidative stress, thereby interfering with cellular function. This study revealed significantly larger deposits of lipofuscin in the lateral pharyngeal wall muscles of patients with severe obstructive sleep apnea (OSA) compared
Kristine Fahl +7 more
wiley +1 more source
Daytime sleepiness and specific food cravings: The moderating role of insulin sensitivity. [PDF]
Romaker EK +7 more
europepmc +1 more source
Light as a chronobiologic countermeasure for long-duration space operations [PDF]
Long-duration space missions require adaptation to work-rest schedules which are substantially shifted with respect to earth. Astronauts are expected to work in two-shift operations and the environmental synchronizers (zeitgebers) in a spacecraft differ ...
Evans, Julie +9 more
core +1 more source
Modified Sleep Apnea Severity Index and Cardiovascular Risk in CPAP‐Intolerant OSA Patients
The modified sleep apnea severity index (mSASI) combines patient anatomy, weight, sleep study metrics, and symptoms into a composite OSA index ranging from 1 (least severe) to 3 (most severe). Our study found that mSASI correlated better with baseline cardiovascular risk measured by the 5‐year Framingham Risk Score compared to the AHI.
Praneet C. Kaki +8 more
wiley +1 more source
Psychometric Validation of the Epworth Sleepiness Scale for Children and Adolescents (ESS-CHAD) in Slovenia: Implications for Public Health Research and Practice. [PDF]
Mlakar A +4 more
europepmc +1 more source
Evaluating Sleep Apnea: In‐Lab Versus at‐Home Recording Time and the Impact of Positional Disease
We evaluated the minimum recording time needed for in‐lab polysomnography (PSG1) and home sleep apnea test Type 3 portable monitoring (HSAT) to accurately reflect the full‐night apnea–hypopnea index (AHI) in patients with suspected obstructive sleep apnea (OSA).
Raquel Chartuni Pereira Teixeira +1 more
wiley +1 more source
Immersive NREM2 dreaming preserves subjective sleep depth against declining sleep pressure. [PDF]
Michalak A +11 more
europepmc +1 more source
Abstract Background Clinical outcome assessments (COAs) are essential for evaluating symptom severity, treatment response, and disease progression in Parkinson's disease (PD). As clinical knowledge evolves, it is necessary to revisit the recommendation status on the COAs to ensure their continued relevance and validity. Objectives To provide an updated
Evita Papathoma +14 more
wiley +1 more source
Sleep disorders and their clinical significance in children with Down syndrome [PDF]
Stores, G., Stores, Rebecca
core +1 more source
Abstract Background α‐synuclein seeding amplification assay (α‐synuclein SAA) development as a diagnostic biomarker for Parkinson's disease (PD) has shown promising results over the past decade. However, the utility of these assays in the prediction of disease progression is unclear.
Daniel Belete +5 more
wiley +1 more source

