Results 91 to 100 of about 178,510 (288)
Advanced Science, EarlyView.The study elucidates that paternal preconception stress can drive offspring hyperresponsivity of the stress system via hypomethylation of a specific DNA region in sperm. This key link is confirmed in a cohort of prospective fathers: the epigenetic alteration is associated with elevated stress hormone levels.
Mengxi Lu +10 more
wiley +1 more source
Comparative Morphology: the revival of the Sleeping Beauty [PDF]
, 2015 En este trabajo comparto mis reflexiones acerca del apogeo de la morfología comparada durante la escuela alemana de la Filosofía Natural. Propongo que esta corriente epistemológica nace como una reacción de los intelectuales de la época a las terribles ...
Abdala, Virginia Sara Luz
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Advanced Science, EarlyView.Biological rhythms coordinate physiology, from genes to behavior. Study of circadian rhythms in brain tissue is constrained by limited throughput and spatial and temporal information quality. A new platform for high‐throughput, long‐term multiplexed fluorescent live imaging of circadian rhythms in brain slices is introduced.
Marco Ferrari +3 more
wiley +1 more source
Self-Locating Belief and Updating on Learning [PDF]
, 2020 Self-locating beliefs cause a problem for conditionalization. Miriam Schoenfield offers a solution: that on learning E, agents should update on the fact that they learned E.
Bradley, Darren
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AGING MEDICINE, EarlyView.Bibliometric analysis reveals rising global research on physical activity and elderly health, dominated by developed nations. Key hotspots include healthy aging, physical activity's mental health benefits, and VR exercise interventions. Promoting physical activity is vital for healthy aging, requiring greater technology integration and research from ...
Hongman Wang +3 more
wiley +1 more source
Advanced Intelligent Discovery, EarlyView.scTIGER2.0 is a deep‐learning framework that infers gene regulatory networks from single‐cell RNA sequencing data. By integrating correlation, pseudotime ordering, deep learning and bootstrap‐based significance testing, it reduces false positives and reveals directional gene interactions.
Nishi Gupta +3 more
wiley +1 more source
Advanced Intelligent Systems, EarlyView.This study proposes a robust, generalizable new approach for facial type diagnosis. Based on landmark detection and pose normalization, a 94.7% diagnostic accuracy is achieved by Combined Heatmap Regression and Coordinate Regression network. This research makes the AI‐generated preliminary diagnosis more interpretable and reducing the impact of ...
Qianyang Xie +12 more
wiley +1 more source
SDPR–STK38 axis controls the proliferation–differentiation balance in alveolar type II cells
Animal Models and Experimental Medicine, EarlyView.The present study identifies SDPR as a pivotal regulator orchestrating the balance between proliferation and differentiation in alveolar type II (AT2) cells. In SDPR+/+ cells, SDPR binds to and inhibits STK38 activity, thereby sustaining GSK‐3β signaling functionality to promote cyclin D1 degradation and maintain cell cycle homeostasis.
Jie Wang +6 more
wiley +1 more source
Disease Models & Mechanisms, 2016 The Wistar Kyoto (WKY) rat and the spontaneously hypertensive (SHR) rat inbred strains are well-established models for human crescentic glomerulonephritis (CRGN) and metabolic syndrome, respectively.
Ana Isabel Garcia Diaz +6 more
doaj +1 more source
Immortal Beauty: Does Existence Confirm Reincarnation? [PDF]
I argue that a popular view about self-locating evidence implies that there are cases in which agents have surprisingly strong evidence for their own reincarnation. The central case is an ‘Immortal Beauty' scenario, modelled after the well-known Sleeping
Jäger, Jens
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