Results 101 to 110 of about 178,510 (288)

Immune Complexes Shape the Pathogenicity of Autoantibodies in Systemic Autoimmune Diseases: Insights From an FcγRIIIA‐Reporter Assay

open access: yesArthritis &Rheumatology, EarlyView.
Objective Immune complexes (ICs), formed by autoantigen and autoantibody, play a pathogenic role in systemic autoimmune diseases through stimulation of Fcγ receptors (FcγR). However, studies investigating bioactivity of circulating ICs across various diseases remain limited.
Koji Suzuki   +8 more
wiley   +1 more source

AN ANALYSIS OF DIRECTIVE SPEECH ACTS BY SEARLE THEORY IN “SLEEPING BEAUTY” MOVIE SCRIPT

open access: yesJournal of English Education and Teaching, 2018
This research aims to find out the types of Directive Speech Acts by the characters in “Sleeping Beauty” movie script based on the theory that proposed by Searle theory and analyze the types of directive speech acts that most frequently used in the movie
Fara Della, Barnabas Sembiring
doaj   +1 more source

Clock genes regulate Ca2+ signaling and mitochondrial bioenergetics to inhibit Sjogren's disease

open access: yesArthritis &Rheumatology, Accepted Article.
Objective Although Ca2+ signaling and metabolism have been identified as key determinants for the development of Sjogren's disease (SjD), the intricate connection between them and salivary gland physiology remains poorly understood. Methods Fluorescence‐based Ca2+ imaging, RNA seq, and mitochondrial activity were used to investigate the effects of ...
Viktor R. Drel   +12 more
wiley   +1 more source

Serotonin 5‐HT7 receptor signaling in neuropsychiatric disorders

open access: yesBulletin of the Korean Chemical Society, EarlyView.
5‐HT7R recruits Gs, G12, and β‐arrestin signaling to regulate neuronal plasticity, circuit function, and kinase‐linked intracellular responses. This review summarizes how these pathway‐selective modules contribute to autism spectrum disorder, depression, and schizophrenia, highlighting 5‐HT7R as a pathway‐informed therapeutic target. Abstract Serotonin
Eunseo Park, Hyunah Choo
wiley   +1 more source

Marine silicon for biomedical sustainability

open access: yesBMEMat, EarlyView.
Schematic illustrating marine silicon for biomedical engineering. Abstract Despite momentous divergence from oceanic origin, human beings and marine organisms exhibit elemental homology through silicon utilization. Notably, silicon serves as a critical constituent in multiple biomedical processes.
Yahui Han   +3 more
wiley   +1 more source

Boston University Chamber Orchestra, November 19, 2013 [PDF]

open access: yes, 2013
This is the concert program of the Boston University Chamber Orchestra performance on Tuesday, November 19, 2013 at 8:00 p.m., at the Tsai Performance Center, 685 Commonwealth Avenue, Boston, Massachusetts. Works performed were Symphony No. 34 in C major,
School of Music, Boston University
core  

Enhanced strategies for cuproptosis‐like death in bacterial infection treatment

open access: yesBMEMat, EarlyView.
This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang   +7 more
wiley   +1 more source

Nicosia-Concerted Retailing and Tourism Strategies to Awaken a Neglekted and Sleeping Beauty [PDF]

open access: yes
Nicosia, the last divided European city, is only able to skim a small portion of the tourist purchasing power compared to the other tourism strongholds of the island and, at the same time, does not utilize the existing cultural potential in an efficient ...
Gronau, Werner   +2 more
core   +1 more source

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