Results 141 to 150 of about 178,510 (288)

Enhanced Biosafety of the Sleeping Beauty Transposon System by Using mRNA as Source of Transposase to Efficiently and Stably Transfect Retinal Pigment Epithelial Cells. [PDF]

Biomolecules, 2023
Harmening N, Johnen S, Izsvák Z, Ivics Z, Kropp M, Bascuas T, Walter P, Kreis A, Pajic B, Thumann G.   +9 more
europepmc   +1 more source

Pig transgenesis by Sleeping Beauty DNA transposition [PDF]

, 2011
A Ciuffi, A Hofmann, A Onishi, A Wilber, AB Tolstrup, AE Davidson, AJ Dupuy, Anders Lade Nielsen, AR Schroder, Arne Lund Jørgensen, B Moldt, Brian Dall Schyth, Brian Moldt, C Kubota, CB Whitelaw, D Garrick, DA Yergeau, G Liu, Gábor Vajta, H Singh, H Zayed, Henrik Callesen, I Wilmut, IA Polejaeva, Ida E. Holm, J Betthauser, Jacob Giehm Mikkelsen, Jannik E. Jakobsen, JB Cibelli, JG Mikkelsen, JR Ohlfest, Juan Li, K Naruse, KJ Clark, KJ Clark, Kjeld Dahl Winther, KW Park, KW Park, L Lai, L Liu, L Mates, L Sinzelle, Lars Bolund, Lin Lin, M Hirabayashi, M Schorpp, MB Nottle, Mette Schmidt, NH Staunstrup, NL Webster, P Leahy, Peter M. Kragh, PM Kragh, PM Kragh, RA Cabot, RE Hammer, RS Mitchell, S Hyun, S Watanabe, SR Yant, SR Yant, SR Yant, T Dalsgaard, T Wakayama, T Wakayama, TJ Vigdal, Y Du, Y Kato, Ying Liu, Z Ivics, Z Izsvak, Z Izsvak   +71 more
core   +1 more source

Psychodermatology of the Female: Hormones, Skin and Mental Health Across the Lifespan

JEADV Clinical Practice, EarlyView.
Hormonal transitions across the female lifespan shape skin disease and psychiatric comorbidity through the brain–skin axis and Neuro‐Immuno‐Cutaneous‐Endocrine (NICE) network. This narrative review links puberty, menstruation, pregnancy, postpartum and menopause to dermatologic and psychosocial outcomes.
Sheila Sharifi, Jessica Gulati, Veranca Shah, Keira Barr, Mohammad Jafferany   +4 more
wiley   +1 more source

Sleeping beauty generated CD19 CAR T-Cell therapy for advanced B-Cell hematological malignancies. [PDF]

Front Immunol, 2022
Singh H, Srour SA, Milton DR, McCarty J, Dai C, Gaballa MR, Ammari M, Olivares S, Huls H, De Groot E, Marin D, Petropoulos D, Olson AL, Anderlini P, Im JS, Khouri I, Hosing CM, Rezvani K, Champlin RE, Shpall EJ, Cooper LJN, Kebriaei P.   +21 more
europepmc   +1 more source

Startups Driving Artificial Intelligence Into Clinical Dermatology

JEADV Clinical Practice, EarlyView.
ABSTRACT Artificial intelligence (AI) is rapidly transitioning from innovation to routine clinical application in dermatology. This review examines how AI‐enabled technologies are being developed and integrated across diverse clinical purposes and workflows.
Dominique Du Crest, Benjamin Miguel Monteagudo, Stanislas Vandier, Mullarkey Dan, Svedenhag Per, Jon Friis, Monisha Madhumita, Lilit Garibyan, Tu‐Anh Duong, Merete Haedersdal, Vinzent Kevin Ortner   +10 more
wiley   +1 more source

Engineered Sleeping Beauty transposase redirects transposon integration away from genes. [PDF]

Nucleic Acids Res, 2022
Miskey C, Kesselring L, Querques I, Abrusán G, Barabas O, Ivics Z.   +5 more
europepmc   +1 more source

Enriched Environment Enhances Motor Function in Mice With Cerebral Infarction by Promoting mTOR‐Dependent Autophagy in the Contralateral Dentate Nucleus

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Although environmental enrichment (EE) promotes post‐stroke motor recovery, the mechanisms underlying its regulation of cerebellar dentate nucleus (DN) plasticity remain unclear; this study therefore investigated how EE coordinates autophagy, mitochondrial homeostasis, and synaptic remodeling in the contralateral DN to facilitate functional ...
Chuan‐Jie Wang, Ke‐Wei Yu, Jun‐Fa Wu, Feng Tao   +3 more
wiley   +1 more source

Transgene Expression and Transposition Efficiency of Two-Component Sleeping Beauty Transposon Vector Systems Utilizing Plasmid or mRNA Encoding the Transposase. [PDF]

Mol Biotechnol, 2023
Tschorn N, van Heuvel Y, Stitz J.
europepmc   +1 more source

Degradable Nanocarriers Capable of Gene Delivery Derived from pH‐Responsive Polyester: RROP Copolymerization Between Cyclic Ketene Acetals

Macromolecular Rapid Communications, EarlyView.
Polyesters with inherent pH‐sensitivity are prepared through radical ring‐opening polymerization between cyclic ketene acetals. These polyesters demonstrate great potential as alternatives to conventional polycations for fabricating hybrid nanoparticles.
Yiyi Deng, Jonas Debbeler, Anja Traeger, Jens Gaitzsch   +3 more
wiley   +1 more source

Universal allogeneic CAR T cells engineered with Sleeping Beauty transposons and CRISPR-CAS9 for cancer immunotherapy. [PDF]

Mol Ther, 2022
Tipanee J, Samara-Kuko E, Gevaert T, Chuah MK, VandenDriessche T.   +4 more
europepmc   +1 more source