Results 101 to 110 of about 926,703 (286)

Quantifying the Impact of Ocrelizumab on Paramagnetic Rim Lesions in Multiple Sclerosis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Paramagnetic rim lesions (PRLs) are a subset of chronic active multiple sclerosis (MS) lesions marked by iron‐laden microglia and macrophages. Ocrelizumab, a monoclonal antibody targeting CD20+ B cells, suppresses acute MS activity, but its effect on PRLs remains unclear. In a longitudinal study of 29 ocrelizumab‐treated patients with at least
Kimberly H. Markowitz, Neha V. Safi, Iliana Pliska‐Bloch, Ulrike W. Kaunzner, Ha Luu, Mert Sisman, Yi Wang, Thanh D. Nguyen, Sandra Hurtado Rúa, Susan A. Gauthier   +9 more
wiley   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

On calculating the slice genera of 11- and 12-crossing knots

, 2016
This paper contains the results of efforts to determine values of the smooth and the topological slice genus of 11- and 12-crossing knots. Upper bounds for these genera were produced by using a computer to search for genus one concordances between knots.
Lewark, Lukas, McCoy, Duncan
core  

Choroid Plexus Enlargement and USPIO‐Based Inflammatory Feature in Cerebral Small Vessel Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective The choroid plexus (CP) is a key component of the blood–cerebrospinal fluid barrier (BCSFB), but its mechanism of action in cerebral small vessel disease (CSVD) remains unclear. This study investigated CP volume (CPV) alterations and their association with conventional imaging markers in CSVD and explored the underlying role of ...
Yongqiang Qu, Xiaoning Ren, Cuihua Fan, Chun Li, Lijie Zhang, Zaiqiang Zhang, Shaowu Li, Zhongmeng Lai, Bin Cai, Ying Fu, Yi Lin, Zhibao Zhu   +11 more
wiley   +1 more source

Shape Analysis of 3D Head Scan Data for U.S. Respirator Users

EURASIP Journal on Advances in Signal Processing, 2010
In 2003, the National Institute for Occupational Safety and Health (NIOSH) conducted a head-and-face anthropometric survey of diverse, civilian respirator users.
Slice DennisE, Benson Stacey, Zhuang Ziqing, Lynch Stephanie, Viscusi DennisJ   +4 more
doaj  

Effect of simultaneous multislice imaging, slice properties, and repetition time on the measured magnetic resonance biexponential intravoxel incoherent motion in the liver.

PLoS ONE
ObjectivesThis study aims to investigate the previously reported dependency of intravoxel incoherent motion (IVIM) parameters on simultaneous multislice (SMS) acquisition and repetition time (TR).
Martin Loh, Tobit Führes, Christoph Stuprich, Thomas Benkert, Sebastian Bickelhaupt, Michael Uder, Frederik Bernd Laun   +6 more
doaj   +1 more source

Advancing Age Modulates Associations Between Cognitive Impairment and Brain Volumes in Early MS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Introduction Cognitive impairment is common in multiple sclerosis (MS), but manifestations following the first demyelinating event are relatively unexplored. We investigated cross‐sectional associations between magnetic resonance imaging (MRI)–derived brain volumes and the presence of cognitive impairment outcomes five years after the first ...
Piriyankan Ananthavarathan, Marco Pitteri, Michael Foster, Sara Collorone, Sara Salama, Elisa Colato, Ferran Prados, Baris Kanber, Marios Yiannakas, Claudia A. M. Gandini Wheeler‐Kingshott, Indran Davagnanam, Frederik Barkhof, Declan Chard, Olga Ciccarelli, Ahmed Toosy   +14 more
wiley   +1 more source

Establishing Validity of SLICE –As an Assessment Instrument of Long Case

Journal of Islamic International Medical College, 2019
Objective: To establish the content and construct validity of Structured Long Interview and Clinical Examination(SLICE) as an instrument for the assessment of long case. Study Design: This was a quantitative analytical study. Place and Duration of Study:
Abdul Ghani Waseem , Shamaila Sharif , Muhammad Saqib Habib , Rehan Ahmed Khan , Usman Hameed , Adil Hameed
doaj  

Prognostic Value of Optic Nerve Sheath Diameters after Acute Ischemic Stroke According to Slice Thickness on Computed Tomography

Diagnostics
The optic nerve sheath diameter (ONSD) can predict intracranial pressure and outcomes in neurological disease, but it remains unclear whether a small ONSD can be accurately measured on routine CT images with a slice thickness of approximately 4–5 mm.
Han-Bin Lee, Sang Hoon Oh, Jinhee Jang, Jaseong Koo, Hyo Jin Bang, Min Hwan Lee   +5 more
doaj   +1 more source

Optimization of Selective Radio Frequency Pulses for Simultaneous Multi-Slice MRI

Chinese Journal of Magnetic Resonance, 2018
Simultaneous multi-slice magnetic resonance imaging (MRI) has attracted much research interests recently due to its advantages in increasing signal-to-noise ratio (SNR) and decreasing acquisition time.
LU Shan, CHANG Yan, QIAN Song-song, SHI Bo, YANG Xiao-dong   +4 more
doaj   +1 more source