Results 61 to 70 of about 922,264 (259)
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Visualization features of canalis sinuosus with cone beam computed tomography
Indian Journal of Dental Research, 2019 Introduction: One of the key stages of evaluating an edentulous ridge prior to dental implant placement is the analysis of neighboring anatomical structures such as canalis sinuosus (CS) with cone-beam computed tomography (CBCT).
Yuri G Sedov +5 more
doaj +1 more source
, 2023 AbstractThis short paper takes initial steps towards developing a novel approach, called log slicing, that aims to answer a practical question in the field of log analysis: Can we automatically identify log messages related to a specific message (e.g., an error message)?
Dawes, J.H., Shin, D., Bianculli, D.
openaire +3 more sources
Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin
Molecular Oncology, EarlyView.Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon +4 more
wiley +1 more source
Efficient and Secure 5G Core Network Slice Provisioning Based on VIKOR Approach
IEEE Access, 2019 Network slicing in 5G is expected to essentially change the way in which network operators deploy and manage vertical services with different performance requirements.
Xin Li +3 more
doaj +1 more source
Analysis of MRI Slices of Hamstring Avulsion Injury using Histogram [PDF]
Journal of Clinical and Diagnostic Research, 2018 Introduction: Hamstring avulsion injury can be defined as improper functioning of the hamstring muscles due to external stress or strain. The detachment of hamstring muscular region from the tendons occurs under severe conditions.
TR Thamizhvani +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova +25 more
wiley +1 more source
Precise spatial and temporal control of oxygen within in vitro brain slices via microfluidic gas channels. [PDF]
PLoS ONE, 2012 The acute brain slice preparation is an excellent model for studying the details of how neurons and neuronal tissue respond to a variety of different physiological conditions. But open slice chambers ideal for electrophysiological and imaging access have
Gerardo Mauleon +2 more
doaj +1 more source
Covariance-Adaptive Slice Sampling [PDF]
, 2010 We describe two slice sampling methods for taking multivariate steps using the crumb framework. These methods use the gradients at rejected proposals to adapt to the local curvature of the log-density surface, a technique that can produce much better ...
Neal, Radford M., Thompson, Madeleine
core +1 more source
FEBS Open Bio, EarlyView.Chemotherapies such as doxorubicin can have toxic effects on healthy cardiovascular/heart tissue. Following up on a doxorubicin toxicity study in mice without tumors where nitrate water was cardioprotective (lessened toxicity), this study with tumor‐bearing mice undergoing doxorubicin treatment showed no negative effect of nitrate and nitrite on drug ...
Rama D. Yammani +7 more
wiley +1 more source