Results 31 to 40 of about 46,997 (268)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Hydrodynamical Study of Creeping Maxwell Fluid Flow through a Porous Slit with Uniform Reabsorption and Wall Slip

Mathematics, 2020
The present theoretical study investigates the influence of velocity slip characteristics on the plane steady two-dimensional incompressible creeping Maxwell fluid flow passing through a porous slit with uniform reabsorption.
Hameed Ullah, Dianchen Lu, Abdul Majeed Siddiqui, Tahira Haroon, Khadija Maqbool   +4 more
doaj   +1 more source

The role of relaxation and retardation phenomenon of Oldroyd-B fluid flow through Stehfest’s and Tzou’s algorithms

Nonlinear Engineering, 2022
Delayed response (delay of the elasticity) and time needed for initial stress can lead to relaxation and retardation phenomenon; this is because of the consistent behavior of viscoelastic fluid on thermodynamic principles.
Awan Aziz Ullah, Riaz Samia, Abro Kashif Ali, Siddiqa Ayesha, Ali Qasim   +4 more
doaj   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

A time dependent slip flow of a couple stress fluid between two parallel plates through state space

Journal of Taibah University for Science, 2018
In this work, the time dependent flow of an incompressible couple stress fluid passing two infinite parallel plates is investigated. The fluid motion is generated by applying a constant pressure gradient together with a sudden motion of one of the two ...
S. S. Ilani, E. A. Ashmawy
doaj   +1 more source

Modelling laminar transport phenomena in a Casson rheological fluid from an isothermal sphere with partial slip in a non-Darcy porous medium [PDF]

Theoretical and Applied Mechanics, 2013
The flow and heat transfer of Casson fluid from a permeable isothermal sphere in the presence of slip condition in a non-Darcy porous medium is analyzed. The sphere surface is maintained at a constant temperature. The boundary layer conservation
Prasad Ramachandra V., Rao Subba A., Reddy Bhaskar N., Bég Anwar O.   +3 more
doaj   +1 more source

Slip and no-slip temperature boundary conditions at the interface of porous, plain media: Convection [PDF]

International Journal of Heat and Mass Transfer, 1994
Near the interface of porous plain media, convective heat transfer may be noticeably affected by the nonuniformity of the phase distributions. The boundary effects are modeled by using interfacial slip or no-slip temperature boundary conditions. The latter uses a variable transverse total diffusivity giving a continuous variation of the temperature ...
Sahraoui, M., Kaviany, Massoud
openaire   +2 more sources

Translating whole‐genome doubling into precision medicine in cancer

Molecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

FEEDBACK BOUNDARY OF 4:1 ROUNDED CONTRACTION SLIP FLOW FOR OLDROYD-B FLUID BY FINITE ELEMENT [PDF]

Journal of Engineering Science and Technology, 2018
The driven force feedback in viscoelastic flow is a technique to enforce converged solution of Oldroyd-B fluid on the basis of semi-implicit TaylorGalerkin finite element method for 4:1 contraction geometry with rounded corner meshes.
NAWALAX THONGJUB
doaj