Results 51 to 60 of about 2,631,685 (238)

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Enhanced heat transfer and fluid motion in 3D nanofluid with anisotropic slip and magnetic field

Open Physics
A mathematical model is envisaged that discusses the motion of 3D nanofluids (NFs) with anisotropic slip influence magnetic field past a stretching sheet.
Li Shuguang, Tarakaramu Nainaru, Khan Muhammad Ijaz, Sivakumar Narsu, Satya Narayana Panyam Venkata, Abdullaev Sherzod, Tamam Nissren, Eldin Sayed M.   +7 more
doaj   +1 more source

Direct Numerical Simulation of Turbulent Channel Flow with Spanwise System Rotation and Velocity Slip on Suction Wall [PDF]

Journal of Applied Fluid Mechanics
Direct numerical simulations are conducted to investigate the turbulent flow of an incompressible Newtonian fluid in a channel at a fully-developed state. The channel rotates steadily around its spanwise axis.
A. Moosaie, Zh. Najafi-Kashkooli, H. I. Andersson   +2 more
doaj   +1 more source

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Thermomechanical Fatigue and Creep–Fatigue Interaction of Inconel 718 Additively Manufactured by Laser Beam Powder Bed Fusion

Advanced Engineering Materials, EarlyView.
Thermomechanical fatigue tests of laser beam powder bed fusion (PBF‐LB) Inconel 718 show that the additively manufactured material reaches almost the lifetimes of conventionally‐rolled material under no‐dwell conditions. Introducing dwell times at the maximum temperature markedly reduces the lifetimes due to pronounced grain boundary sliding associated
Stefan Guth, Tomáš Babinský, Jan Lars Riedel, Wen Hao Kan, Aijun Huang, Martin Heilmaier, Ivo Šulák   +6 more
wiley   +1 more source

Boundary Condition for the Electric Field in Earth's Core Models With Conducting Boundaries

Geophysical Research Letters
The Earth's core flows are governed by magnetohydrodynamic equations, where boundary conditions determine how the electric field in the liquid core relates to that in the conducting boundaries.
J. Rekier, S. A. Triana, B. Buffett
doaj   +1 more source

Finite Integral Transform Based Solution of Second Grade Fluid Flow between Two Parallel Plates [PDF]

Journal of Applied and Computational Mechanics, 2019
The importance of the slip flow over the no-slip condition is widely accepted in microscopic scaled domains with the direct impact on microfluidic and nanofluidic systems. The popular Navier Stoke’s (N-S) flow model is largely utilized with the slip flow
Jaideep Dutta, Balaram Kundu
doaj   +1 more source

Towards Defect Phase Diagrams: From Research Data Management to Automated Workflows

Advanced Engineering Materials, EarlyView.
A research data management infrastructure is presented for the systematic integration of heterogeneous experimental and simulation data required for defect phase diagrams. The approach combines openBIS with a companion application for large‐object storage, automated metadata extraction, provenance tracking and federated data access, thereby supporting ...
Khalil Rejiba, Sang‐Hyeok Lee, Christina Gasper, Martina Freund, Sandra Korte‐Kerzel, Ulrich Kerzel   +5 more
wiley   +1 more source

A Simplified Laminar Flow Model for the Pultrusion of Glass Fiber/Polyethylene Terephthalate Commingled Yarns

Advanced Engineering Materials, EarlyView.
A simplified thermoplastic pultrusion model is developed to predict thermal fields in glass fiber/polyethylene terephthalate (GF/PET) composites with reduced computational cost. By combining effective material homogenization, validation against literature data, and Gaussian‐process‐based optimization, the study reveals how heating limits, pulling speed,
Elder Soares, Nadège Bouchonneau, Christian Jochum, Donald Radford   +3 more
wiley   +1 more source