Results 41 to 50 of about 6,223,371 (193)

Current Slip and Strain Rate Distribution Along the Ganzi-Yushu-Xianshuihe Fault System Based on InSAR and GPS Observations

Frontiers in Earth Science, 2022
The Ganzi-Yushu-Xianshuihe fault (GYXSF), a large strike-slip fault located on the east side of the Tibetan Plateau, has seen high seismic activity in recent years.
Wenting Zhang, Wenting Zhang, Lingyun Ji, Lingyun Ji, Lingyun Ji, Liangyu Zhu, Liangyu Zhu, Chuanjin Liu, Chuanjin Liu, Fengyun Jiang, Fengyun Jiang, Xiaoxue Xu, Xiaoxue Xu   +12 more
doaj   +1 more source

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source

Probabilistic Assessment of Slip Rates and Their Variability Over Time of Offshore Buried Thrusts: A Case Study in the Northern Adriatic Sea

Frontiers in Earth Science, 2021
When sedimentation rates overtake tectonic rates, the detection of ongoing tectonic deformation signatures becomes particularly challenging. The Northern Apennines orogen is one such case where a thick Plio-Pleistocene foredeep sedimentary cover blankets
Yuri Panara, Yuri Panara, Francesco Emanuele Maesano, Chiara Amadori, Chiara Amadori, Jakub Fedorik, Giovanni Toscani, Giovanni Toscani, Roberto Basili   +8 more
doaj   +1 more source

MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation

FEBS Open Bio, EarlyView.
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima, Kotone Watanabe, Grigorii Sultanakhmetov, Aoi Fukuchi, Keiya Ito, Sawako Shimizu, Taro Saito, Akiko Asada, Kanae Ando   +8 more
wiley   +1 more source

Using fluorescence fluctuation spectroscopy to quantify molecular dynamics within cells

FEBS Open Bio, EarlyView.
Microscopy techniques like fluorescence correlation spectroscopy (FCS) and number and brightness analysis (N&B) allow to quantify concentrations, diffusion rates, and oligomerization of fluorescently labeled molecules in the living cell. In this protocol the principles of how to set up these types of experiments are described including calibration ...
Mark A. Hink
wiley   +1 more source

A Workflow to Accelerate Microstructure‐Sensitive Fatigue Life Predictions

Advanced Engineering Materials, EarlyView.
This study introduces a workflow to accelerate predictions of microstructure‐sensitive fatigue life. Results from frameworks with varying levels of simplification are benchmarked against published reference results. The analysis reveals a trade‐off between accuracy and model complexity, offering researchers a practical guide for selecting the optimal ...
Luca Loiodice, Krzysztof S. Stopka, Michael D. Sangid   +2 more
wiley   +1 more source

Analysis and Experimental Investigation of Steering Kinematics of Driven Steering Crawler Harvester Chassis

Agriculture, 2023
In the context of automatic driving, the analysis of the steering motion characteristics is critical for enhancing the efficiency of crawler harvesters.
Yanxin Wang, Chengqian Jin, Tengxiang Yang, Tingen Wang, Youliang Ni   +4 more
doaj   +1 more source

Fault slip-rate variations during crustal-scale strain localisation, central Italy [PDF]

, 2002
Rates of plate motion are generally uniform over 10–102 Myrs timescales. Faults between tectonic plates might, therefore, be expected to show temporally-uniform slip-rates if the same number of faults remain active. For an extending region of the Eurasia-
Morewood, NC, Michetti, AM, Roberts, GP, Cowie, P, Papanikolaou, I   +4 more
core  

Microstructural Evolution and Vacancy Defect Formation in Mn–Mo–Ni RPV Steel Under Low Cycle Fatigue: Insights From EBSD and PALS

Advanced Engineering Materials, EarlyView.
Low‐cycle fatigue damage in Mn–Mo–Ni reactor pressure vessel steel is examined using a combined electron backscatter diffraction and positron annihilation lifetime spectroscopy approach. The study correlates texture evolution, dislocation substructure development, and vacancy‐type defect formation across uniform, necked, and fracture regions, providing
Apu Sarkar, Dhanadeep Dutta, G. Bharat Reddy   +2 more
wiley   +1 more source

Slip-rate on the Main Köpetdag (Kopeh Dagh) strike-slip fault, Turkmenistan, and the active tectonics of the South Caspian [PDF]

, 2021
We provide the first measurement of strike-slip and shortening rates across the 200-kmlong right-lateral strike-slip Main Köpetdag† Fault (MKDF) in Turkmenistan.
Bezmenov, Yevgeniy, Jackson, J.A., Walker, Richard, R. T. Walker, Gruetzner, Christoph, Mirzin, R., S. Carolin, Begenjev, Geldymurad, Walker, Richard Thomas, Carolin, S., Bezmenov, Y., Rhodes, E.J., R. Mirzin, Carolin, Stacy Anne, Rhodes, Edward J., Rhodes, Ed, J. A. Jackson, N. Dodds, Dodds, N., G. Begenjev, Mousavi, Zahra, Carolin, Stacy, Y. Bezmenov, C. Gruetzner, E. J. Rhodes, Walker, R.T., Mousavi, Z., Jackson, James, Mirzin, Robert, Z. Mousavi, Gruetzner, C., Dodds, Nicholas, Begenjev, G.   +32 more
core   +3 more sources