Results 91 to 100 of about 6,904 (300)

Partial abrasion modeling and variable load characteristics analysis for high-speed load sensing electro-hydrostatic actuator pump of aircraft

open access: yesAdvances in Mechanical Engineering
The load-sensing electro-hydrostatic actuator (LS-EHA) allows to reduce the thermal output and enhance the dynamic characteristics of the more electric aircraft (MEA).
Cun Shi   +4 more
doaj   +1 more source

On the type material of Scyllarides deceptor Holthuis, 1963 (Crustacea: Decapoda: Scyllaridae)

open access: yesPapéis Avulsos de Zoologia, 2009
The only specimen listed in the original description of Scyllarides deceptor Holthuis, 1963 is the holotype from São Paulo, Brazil, presently housed in the Leiden Museum.
Marcos Tavares   +2 more
doaj   +1 more source

Wedding slipper

open access: yes, 1975
A wedding slipper of 1850 has a low heel; the slipper of 1830 is flat (from Ladies' dress shoes of the nineteenth ...
Greig, T. Watson   +1 more
core  

Treatment with KCL‐286, a first‐in‐class retinoic acid receptor‐β (RARβ) agonist, ameliorates neuronal DNA damage and inflammation in a mouse model of Alzheimer's disease

open access: yesFEBS Open Bio, EarlyView.
Repair of neuronal DNA damage in Alzheimer's disease by KCL‐286. (A) Amyloid‐β oligomers and plaques impair neuronal DNA repair pathways, leading to DNA double‐strand breaks and glial activation. (B) KCL‐286 activates RARβ/RXR signalling via retinoic acid response elements (RAREs), associated with increased BRCA1 expression, enhanced DNA repair and ...
Natasha Hill   +6 more
wiley   +1 more source

Multi body dynamics of a slipper in swash plate type piston pumps and motors coupled with hydrodynamic analysis of oil-film

open access: yesNihon Kikai Gakkai ronbunshu, 2014
In swash plate type piston pumps and motors, the slippers are used under heavy load. So the slippers are designed as a hydrostatic bearing to ensure reliability.
Kenta SUZUKI   +4 more
doaj   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface

open access: yesFEBS Open Bio, EarlyView.
HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana   +5 more
wiley   +1 more source

Lady's Slipper

open access: yes, 2002
A single lady's slipper fills the foreground against a forested ...
Eastman, Michael H.
core  

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

open access: yesFEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan   +11 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

open access: yesFEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley   +5 more
wiley   +1 more source

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