Results 71 to 80 of about 58,137 (298)

The slipping slipper sign: a simple test with high specificity and positive predictive value for peripheral neuropathy among diabetic patients

open access: yesClinics and Practice, 2012
This study evaluated the ability of the slipping slipper sign (defined as unknowingly losing a slipper while walking) to identify diabetic neuropathy in Jamaican patients. A single question was used to ascertain the presence of the slipping slipper sign (
Krystal A.T. Gayle   +3 more
doaj   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang   +12 more
wiley   +1 more source

First record of the Sculptured Mitten Lobster Parribacus antarcticus (Crustacea, Decapoda, Scyllaridae) from the Cabo Verde Islands (eastern Atlantic) [PDF]

open access: yes, 2019
The lobster genus Parribacuscontains six living and one fossil species (Holthuis 1991; Chan 2010; Nyborg & Garassino 2017). In the Atlantic Ocean, only one living species is known, Parribacus antarcticus(Lund, 1793); it has been recorded in the western ...
Freitas, Rui, Wirtz, Peter
core  

Interrogating the immune landscape of microsatellite stable RAS‐mutated colon cancer

open access: yesMolecular Oncology, EarlyView.
COLOSSUS project RAS‐mutated MSS colon cancer study explored transcriptomics and immune cell density by immunohistochemistry (IHC), Immunoscore (IS), ISIC/TuLIS scores, mutation counts, and detected different prevalences but similar microenvironment composition across immune markers with clinical relevance for future immunotherapy combination ...
Rodrigo Dienstmann   +61 more
wiley   +1 more source

Lobster culture and live transport [PDF]

open access: yes, 1998
Eight species of spiny lobsters, six shallow water and two deep sea species and two slipper or sand lobsters constitute the lobster fishery of ...
Radhakrishnan, E V, Vijayakumaran, M
core  

Float-polishing process and analysis of float-polished quartz [PDF]

open access: yes, 1994
A fluid-mechanical model is developed for the float-polishing process. In this model laminar flow between the sample and the lap results in pressure gradients at the grooves that support the sample on a fluid layer. The laminar fluid motion also produces
Baselt, D. R.   +4 more
core   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch   +13 more
wiley   +1 more source

Vesicle dynamics in confined steady and harmonically modulated Poiseuille flows

open access: yes, 2018
We present a numerical study of the time-dependent motion of a two-dimensional vesicle in a channel under an imposed flow. In a Poiseuille flow the shape of the vesicle depends on the flow strength, the mechanical properties of the membrane, and the ...
Benyoussef, Abdelilah   +6 more
core   +1 more source

Dual PI3K/AKT and CDK4/6 inhibition reveals selective sensitivity in an SHH medulloblastoma stem cell model

open access: yesMolecular Oncology, EarlyView.
Targeted therapy was evaluated in SHH medulloblastoma using neuroepithelial stem cell (NES) and tumor‐derived NES‐like (tNES) models in 2D monolayers and 3D spheroids. PI3K, AKT, and CDK4/6 inhibitors had minimal effects in NES but markedly reduced viability and growth and induced apoptosis in tNES cells, revealing distinct therapeutic vulnerabilities.
Monika Lukoseviciute   +4 more
wiley   +1 more source

"Unlike actors, politicians or eminent military men”: The meaning of hard work in working class autobiography [PDF]

open access: yes, 2010
Copyright @ 2010 The Autobiography ...
Hansford Charles Lewis   +4 more
core   +1 more source

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