Results 51 to 60 of about 6,904 (300)

Dynamic Prediction Model for Uneven Slipper Wear Under Complex Lubrication Conditions Considering Lubrication–Wear Coupling

Lubricants
It is difficult to experimentally determine the real-time wear coefficient of a slipper pair under complex lubrication conditions. To address this challenge, this study proposes a predictive method for slipper wear, eliminating the need for experimental ...
Hu Mo, Shigang Qin, Wei Zhou, Yunan Yang, Penghui Duan, Fu Peng   +5 more
doaj   +1 more source

Loss of proton‐sensing TDAG8 increases tumor progression in mouse models of colon cancer

Molecular Oncology, EarlyView.
Loss of the pH‐sensing receptor TDAG8 accelerates colorectal cancer progression in mice. Animals lacking TDAG8 expression had increased tumor growth, DNA damage, and recruitment of tumor‐associated immune cells, including macrophages, neutrophils, and monocytes.
Ermanno Malagola, Yasmine Illi, Anna Bircher, Marijn Wilmink, Rachele F. Malagutti, Solenn Ottié, Cordelia Schuler, Pedro A. Ruiz, Cheryl de Vallière, Klaus Seuwen, Gerhard Rogler, Martin Hausmann   +11 more
wiley   +1 more source

Optimal design of slippers in a radial piston pump (Experiment and simulation under concentric conditions)

Mechanical Engineering Journal
Mechanical components must be designed to prevent wear and seizure. In hydraulic piston pumps, abnormal friction between the piston bore and cylinder as well as bearings can cause failure or breakdown.
Shoichi TAKEMOTO, Yusuke KITAMOTO, Yuki NOJIMA, Toshiharu KAZAMA   +3 more
doaj   +1 more source

Dynamic Analysis of Shearer Traction Unit Considering the Longitudinal Swing

Energies, 2020
Shearer traction failure occurs frequently, which seriously restricts the safe and efficient mining of coal. However, the influence of the shearer’s posture on traction has not been fully considered in the existing research.
Dejian Ma, Xin Zhang, Lirong Wan, Qingliang Zeng, Hongen Ge   +4 more
doaj   +1 more source

Spatial and single‐nuclei transcriptomics reveals idiosyncratic and generic patterns in papillary and anaplastic thyroid cancers

Molecular Oncology, EarlyView.
Matched spatial transcriptomics and single‐nuclei RNA‐seq were generated for anaplastic and BRAFV600E papillary thyroid cancers revealing generic and tumor‐specific states occurring in cancer cells and in the tumor microenvironment. In this context, cancer dedifferentiation mirrored organoid maturation through ordered thyroid marker gain/loss ...
Adrien Tourneur, Joel Rodrigues Vitória, Manuel Saiselet, Ligia Craciun, Denis Larsimont, Anne Lefort, Frédérick Libert, Carine Maenhaut, Sabine Costagliola, Maxime Tarabichi, Mirian Romitti, Vincent Detours   +11 more
wiley   +1 more source

Study of the influence of slipper parameters on the power efficiency of axial piston pumps

Advances in Mechanical Engineering, 2018
This article presents the influence and impact of the gap between the outer and the inner diameter of the slipper on the performance of axial piston pumps.
Gaston Haidak, Dongyun Wang, E Shiju, Jun Liu   +3 more
doaj   +1 more source

A novel extraction method for useful component of vibration signal combining variational mode decomposition and relative entropy

AIP Advances, 2021
In condition monitoring and prognostics health management, it is very important to extract the useful components of equipment state signals. In this paper, combining variational mode decomposition (VMD) and relative entropy (RE), a novel approach is ...
Yong Zhu, Quanlin Wang, Yangding Wang, Shouqi Yuan, Shengnan Tang, Zhijian Zheng   +5 more
doaj   +1 more source

CEACAM1 participation in breast cancer progression

Molecular Oncology, EarlyView.
In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin, Irina Kube‐Golovin, Anatolii Romaniuk, Gunther Wennemuth   +3 more
wiley   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Nutritional value and characteristics of chitin from slipper lobster (Thenus orientalis) for functional food ingredient [PDF]

BIO Web of Conferences
Slipper lobster lives on the bottom of sandy marine waters. The nutritional content and utilization of its large carapace (50%) can be converted into chitin.
Karnila Rahman, Fauzi Muhammad, Zulfarina, Syah Putra Harifa, Desmylyla Safitry Nazywa, Darmila Ika, Al Fatah Syafiq   +6 more
doaj   +1 more source