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Slits are secreted proteins that bind to Roundabout (Robo) receptors. Slit-Robo signaling is best known for mediating axon repulsion in the developing nervous system. However, in recent years the functional repertoire of Slits and Robo has expanded tremendously and Slit-Robo signaling has been linked to roles in neurogenesis, angiogenesis and cancer ...
Heike Blockus, A. Chédotal
semanticscholar +4 more sources
Dscam1 Forms a Complex with Robo1 and the N-Terminal Fragment of Slit to Promote the Growth of Longitudinal Axons. [PDF]
The Slit protein is a major midline repellent for central nervous system (CNS) axons. In vivo, Slit is proteolytically cleaved into N- and C-terminal fragments, but the biological significance of this is unknown.
Maryam Alavi+9 more
doaj +2 more sources
Robo2 acts in trans to inhibit Slit-Robo1 repulsion in pre-crossing commissural axons
During nervous system development, commissural axons cross the midline despite the presence of repellant ligands. In Drosophila, commissural axons avoid premature responsiveness to the midline repellant Slit by expressing the endosomal sorting receptor ...
Timothy A Evans+3 more
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The Slit of a Spectroscope [PDF]
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William Crookes
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Double-slit photoelectron interference in strong-field ionization of the neon dimer [PDF]
Wave-particle duality is an inherent peculiarity of the quantum world. The double-slit experiment has been frequently used for understanding different aspects of this fundamental concept.
M. Kunitski+15 more
semanticscholar +1 more source
On parallel slit mappings [PDF]
Kôtaro Oikawa, Nobuyuki Suita
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Double Slit to Cross Double Slit to Comprehensive Double Slit Experiments [PDF]
Abstract Young’s double slit experiments, which represent the mystery of quantum mechanics, have been interpreted by quantum probability waves and de Broglie-Bohm’s trajectory/pilot waves. To study in detail, the double slit experiments are extended to the cross double slit experiments.
openaire +2 more sources
New insight into podocyte slit diaphragm, a therapeutic target of proteinuria
Dysfunction of slit diaphragm, a cell–cell junction of glomerular podocytes, is involved in the development of proteinuria in several glomerular diseases. Slit diaphragm should be a target of a novel therapy for proteinuria.
H. Kawachi, Y. Fukusumi
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Beyond Axon Guidance: Roles of Slit-Robo Signaling in Neocortical Formation
The formation of the neocortex relies on intracellular and extracellular signaling molecules that are involved in the sequential steps of corticogenesis, ranging from the proliferation and differentiation of neural progenitor cells to the migration and ...
Yuko Gonda, T. Namba, Carina Hanashima
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