Results 1 to 10 of about 10,284 (151)

Solid Lipid Nanoparticles (SLN): Formulation and Fabrication [PDF]

Pharmaceutical Sciences and Research, 2023
Solid lipid nanoparticles (SLN) have emerged as a novel drug delivery system and have been utilized for delivering various kinds of drugs since the 1990s. These particles may consist of multiple solid lipids, including glycerides, waxes, and fatty acids,
Gabriella F. Punu, Yahdiana Harahap, Qonita Kurnia Anjani, Pietradewi Hartrianti, Ryan F. Donnelly, Delly Ramadon   +5 more
doaj   +2 more sources

Solid Lipid Nanoparticles (SLN) as Ocular Delivery System for Tobramycin

International Journal of Pharmaceutics, 2002
Aim of this study was to evaluate solid lipid nanoparticles (SLN) as carriers for topical ocular delivery of tobramycin (TOB). The SLN were in the colloidal size range (average diameter below 100 nm; polydispersity index below 0.2) and contained 2.5% TOB
Susi Burgalassi, Roberta Cavalli, Patrizia Chetoni   +2 more
exaly   +2 more sources

Perillaldehyde 1,2-Epoxide Loaded SLN-Tailored mAb: Production, Physicochemical Characterization and in Vitro Cytotoxicity Profile in MCF-7 Cell Lines

Pharmaceutics, 2020
We have developed a new cationic solid lipid nanoparticle (SLN) formulation, composed of Compritol ATO 888, poloxamer 188 and cetyltrimethylammonium bromide (CTAB), to load perillaldehyde 1,2-epoxide, and surface-tailored with a monoclonal antibody for ...
Antonello Santini, Patrícia Severino, Olaf K Horbańczuk   +2 more
exaly   +3 more sources

Sargassum wightii ameliorates anxiety-like behaviour and cognitive deficits in rotenone-induced parkinsonian rats [PDF]

Journal of HerbMed Pharmacology, 2023
Introduction: Parkinson’s disease (PD) is a neurodegenerative disorder, basically manifested by motor symptoms. However, there are other associated non-motor features in PD, including depression, anxiety, and cognitive impairments that significantly ...
Bandana Rath, Lalit Mohan Sika, Ikhita Misra, Snigdha Rani Panigrahy, Baidyanath Mishra   +4 more
doaj   +1 more source

Splenectomy in Sickle Cell Haemoglobinopathies from a Tertiary Hospital of Southern Odisha: A Retrospective Study [PDF]

Journal of Clinical and Diagnostic Research, 2022
Introduction: Sickle Cell Disease (SCD) is a common haemoglobinopathy, where spleen is considered to be the first organ to be involved. Although it initially undergoes enlargement, but most often there occurs autosplenectomy. But in some cases, there
Abinash Kumar Panda, Bhupati Bhusan Das, B Swagat Kumar Subudhi, Indrajeet Padhy   +3 more
doaj   +1 more source

Moisturizing effects of solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) using deionized and magnetized water by in vivo and in vitro methods [PDF]

Iranian Journal of Basic Medical Sciences, 2020
Objective(s): The present study aimed to determine and compare moisturizing and occlusion effects of different solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC) using magnetized water and deionized water.Materials and Methods: SLN ...
Susan Sarhadi, Mostafa Gholizadeh, Tina Moghadasian, Shiva Golmohamadzadeh   +3 more
doaj   +1 more source

Routine medical check-up and self-treatment practices among population living in mountainous area of a tribal district of Odisha

National Journal of Physiology, Pharmacy and Pharmacology, 2022
Background: Self-treatment is recognized as one of the global public health issues. Geographical distance, constrained financial resources, and lack of awareness are the main barriers for people in remote areas to access health care.
Manas Ranjan Naik, Satyajit Samal
doaj   +1 more source

A concept to combine a gamma probe with ultrasound imaging for improved localization of sentinel lymph nodes: a feasibility study of the concept

Current Directions in Biomedical Engineering, 2022
This paper presents the proof-of-concept study of an adaptor allowing the combination of a gamma probe with ultrasound (US) imaging, intending to improve the detectability of sentinel lymph nodes (SLNs).
Pashazadeh Ali, Hoeschen Christoph, Grosser Oliver S., Kreissl Michael C., Kupitz Dennis, Boese Axel, Illanes Alfredo, Friebe Michael   +7 more
doaj   +1 more source

Review of commercially available nano-drugs and nano-delivery systems: challenges and perspectives

4 open, 2023
Nano-drugs and nano-delivery systems are rapidly evolving, with new strategies emerging in the current practices. The evolution of these technologies began with modifying the chemical structure, progressing to supramolecular ionic complexes, and ...
Boudovitch Dmitri, Sakaya Aya, Uzundurukan Arife, Leroux Jean-Yve, Fuoco Domenico   +4 more
doaj   +1 more source

An update on the application of nano-scaled carriers against fluconazole-resistant Candida species: nanostructured lipid carriers or solid lipid nanoparticles? [PDF]

Current Medical Mycology, 2019
Background and Purpose: Encapsulation can lead to improved efficacy and safety of antifungal compounds. The attention of scientists has recently turned to biocompatible lipids as the carriers for the delivery of antifungal drugs, such as fluconazole ...
Maryam Moazeni, Majid Saeedi, Hamidreza Kelidari, Mojtaba Nabili, Amirhossein Davari   +4 more
doaj   +1 more source