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Encyclopedia, 2022 Solid lipid nanoparticles (SLNs) are produced from physiologically biocompatible lipids. They have been proven to improve solubility, cellular uptake, and stability, reduce enzyme degradation, and prolong the circulation time of various drugs.
Thi-Thao-Linh Nguyen, Van-An Duong
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Solid Lipid Nanoparticles vs. Nanostructured Lipid Carriers: A Comparative Review [PDF]
Pharmaceutics, 2023 Solid–lipid nanoparticles and nanostructured lipid carriers are delivery systems for the delivery of drugs and other bioactives used in diagnosis, therapy, and treatment procedures. These nanocarriers may enhance the solubility and permeability of drugs,
Cláudia Viegas +5 more
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Preparation of Nanoparticles of Digoxin Solid Lipid
Chemical Engineering Transactions, 2017 In order to prove the role of solid lipid nanoparticles in oral absorption and bioavailability, the biodegradable monoglyceride with low toxicity and good biocompatibility is used as lipid materials to prepare nanoparticles of digoxin solid lipid and ...
Ping Luo, Yangwu Liu
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Design of Experiments in the Formulation and Characterization of 3D-Printed Vaginal Films Loaded with Curcumin Solid Lipid Nanoparticles for Cervical Dysplasia [PDF]
PharmaceuticalsBackground/Objectives: Cervical dysplasia, a precursor to cervical cancer, represents a significant global health challenge, particularly in regions like Central America, Africa, and Southeast Asia.
Mahek Gulani +12 more
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Optimization of the Conditions of Solid Lipid Nanoparticles (SLN) Synthesis
Molecules, 2022 Solid lipid nanoparticles (SLNs) have been synthesized as potential drug delivery systems. They are classified as solid lipid nanocarriers that can successfully carry both hydrophilic and hydrophobic drugs.
Ewelina Musielak +2 more
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Solid Lipid Nanoparticles (SLN): Formulation and Fabrication
Pharmaceutical Sciences and Research, 2023 Solid lipid nanoparticles (SLN) have emerged as a novel drug delivery system and have been utilized for delivering various kinds of drugs since the 1990s. These particles may consist of multiple solid lipids, including glycerides, waxes, and fatty acids,
Gabriella F. Punu +5 more
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On the Structure of Solid Lipid Nanoparticles [PDF]
Small, 2019 AbstractSolid lipid nanoparticles (SLNs) have a crystalline lipid core which is stabilized by interfacial surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their ability to store and release organic molecules can be tailored through the identity of the lipids and surfactants used.
Demi L. Pink +6 more
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Molecules, 2021 Treatment of herpes simplex infection requires high and frequent doses of oral acyclovir to attain its maximum therapeutic effect. The current therapeutic regimen of acyclovir is known to cause unwarranted dose-related adverse effects, including acute ...
Haniza Hassan +5 more
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Pharmaceutics, 2023 Solid lipid nanoparticles promote skin hydration via stratum corneum occlusion, which prevents water loss by evaporation, and via the reinforcement of the skin’s lipid-film barrier, which occurs through the adhesion of the nanoparticles to the stratum ...
Francesca Della Sala +11 more
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Preclinical Evaluation of Lipid-Based Nanosystems
Pharmaceutics, 2021 The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles—SLN, and nanostructured lipid carriers—NLC), nanoemulsions, and liposomes, among others, is widespread [...]
Ana Catarina Silva +1 more
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