Results 31 to 40 of about 2,725,499 (286)

Use of Microfluidics to Prepare Lipid-Based Nanocarriers

Pharmaceutics, 2023
Lipid-based nanoparticles (LBNPs) are an important tool for the delivery of a diverse set of drug cargoes, including small molecules, oligonucleotides, and proteins and peptides. Despite their development over the past several decades, this technology is
Alicia Vogelaar, Samantha Marcotte, Jiaqi Cheng, Benazir Oluoch, Jennica Zaro   +4 more
doaj   +1 more source

Nanopartículas de lipídios sólidos: métodos clássicos de produção laboratorial

Química Nova, 2011
Solid lipid nanoparticles have been extensively investigated as drug delivery systems. These colloidal systems have major advantages compared to others more traditional.
Eliana B Souto, Patrícia Severino, Maria Helena A Santana, Samantha C Pinho   +3 more
doaj   +1 more source

Lipid Nanoparticles for Ocular Gene Delivery

Journal of Functional Biomaterials, 2015
Lipids contain hydrocarbons and are the building blocks of cells. Lipids can naturally form themselves into nano-films and nano-structures, micelles, reverse micelles, and liposomes.
Yuhong Wang, Ammaji Rajala, Raju V. S. Rajala   +2 more
doaj   +1 more source

The use of quantitative analysis and Hansen solubility parameter predictions for the selection of excipients for lipid nanocarriers to be loaded with water soluble and insoluble compounds

Saudi Pharmaceutical Journal, 2020
The aim of these studies was to determine the miscibility of different API with lipid excipients to predict drug loading and encapsulation properties for the production of solid lipid nanoparticles and nanostructured lipid carriers.
Pedzisai A. Makoni, Janeeta Ranchhod, Kasongo WaKasongo, Sandile M. Khamanga, Roderick B. Walker   +4 more
doaj   +1 more source

Lipid Nanoparticles for the Posterior Eye Segment

Pharmaceutics, 2021
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most
Lorena Bonilla, Marta Espina, Patricia Severino, Amanda Cano, Miren Ettcheto, Antoni Camins, Maria Luisa García, Eliana B. Souto, Elena Sánchez-López   +8 more
doaj   +1 more source

Assessment of the Therapeutic Impact of Ivermectin Loaded on Solid Lipid Nanoparticles against Muscular Phase of Murine Trichinosis [PDF]

Zagazig University Medical Journal
Background: Trichinosis is acquired through ingesting the infective larvae in pork meat. Drugs employed for the treatment of trichinosis have a limited bioavailability in addition to the adverse side effects.
Tahani Farag, Mona Almotayam, Asmaa Mohamed, Al-Sayed R. Al-Attar, Ibrahim Aly, Shaimaa Farag, Samar Hammad   +6 more
doaj   +1 more source

SOLID LIPID NANOPARTICLES - EFFECT OF LIPID MATRIX AND SURFACTANT ON THEIR PHYSICAL CHARACTERISTICS [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2004
Solid lipid nanoparticles (SLN) have gained increasing attention as a colloidal drug carrier system, particularly for lipophilic drugs, because SLN combine the advantages of polymeric nanoparticles, fat emulsions, and liposomes but avoiding their ...
Mohamed Abdel-Moaty, Heba Abdel-Salam, Mamdouh Ghorab   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

Fusogenic RNA Nanomodules for Fusion‐Mediated and Multiplexed siRNA Delivery

Advanced Functional Materials, EarlyView.
A fusogenic lipid‐layered RNA nanomodules (L‐CRAMs) enable high‐capacity and long‐lasting siRNA delivery through membrane fusion. These nanomodules carry exceptionally large siRNA payloads, avoid conventional endosomal uptake, and release multiple functional siRNAs through Dicer‐mediated processing.
Sunghyun Moon, Iksoo Jang, Taehyeon Kim, Nayoung Yoon, Kyuha Yum, Jong Bum Lee   +5 more
wiley   +1 more source

New surface-modified solid lipid nanoparticles using N-glutaryl phosphatidylethanolamine as the outer shell

, 2011
Soheila Kashanian1, Abbas Hemati Azandaryani1, Katayoun Derakhshandeh2,3 1School of Chemistry, Nanoscience and Nanotechnology Research Center and Sensor and Biosensor Research Center, Razi University, 2Department of Pharmaceutics, Kermanshah University ...
Kashanian S, null Kashanian, Hemati Azandaryani A, Katayoun Derakhshandeh, Derakhshandeh K, Abbas Hemati Azandaryani   +5 more
core   +1 more source