Resveratrol in Solid Lipid Nanoparticles
Journal of Dispersion Science and Technology, 2012 This article investigates the possibility of producing solid lipid nanoparticles (SLN) as protective vehicle of resveratrol, an antioxidant characterized by a fast trans-cis isomerization. SLN aqueous dispersions were produced by hot melt homogenization technique and characterized.
CARLOTTI, Maria Eugenia +4 more
openaire +2 more sources
Scalable Manufacturing Processes for Solid Lipid Nanoparticles [PDF]
Pharmaceutical Nanotechnology, 2019 Background: Solid lipid nanoparticles offer a range of advantages as delivery systems but they are limited by effective manufacturing processes. Objective: In this study, we outline a high-throughput and scalable manufacturing process for solid lipid nanoparticles.
Anderluzzi, Giulia +3 more
openaire +4 more sources
Native silica nanoparticles are powerful membrane disruptors [PDF]
, 2015 Silica nanoparticles are under development for intracellular drug delivery applications but can also have cytotoxic effects including cell membrane damage.
Alkhammash, Hend I. +3 more
core +1 more source
Roles of reconstituted high-density lipoprotein nanoparticles in cardiovascular disease: A new paradigm for drug discovery [PDF]
, 2020 Epidemiological results revealed that there is an inverse correlation between high-density lipoprotein (HDL) cholesterol levels and risks of atherosclerotic cardiovascular disease (ASCVD).
Huang, Hui +3 more
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Nanopartículas de lipídios sólidos: métodos clássicos de produção laboratorial
Química Nova, 2011 Solid lipid nanoparticles have been extensively investigated as drug delivery systems. These colloidal systems have major advantages compared to others more traditional.
Eliana B Souto +3 more
doaj +1 more source
Localization of dexamethasone within dendritic core-multishell (CMS) nanoparticles and skin penetration properties studied by multi-frequency electron paramagnetic resonance (EPR) spectroscopy [PDF]
, 2016 The skin and especially the stratum corneum (SC) act as a barrier and protect epidermal cells and thus the whole body against xenobiotica of the external environment. Topical skin treatment requires an efficient drug delivery system (DDS).
Anske, M. +8 more
core +1 more source
Solid Lipid Nanoparticles (SLN)
, 2022 Solid lipid nanoparticles (SLN) are nanocarriers in the 10–1000 nm range of a solid core, containing both hydrophilic and hydrophobic active pharmaceutical ingredients. SLNs are composed of well-tolerated and biodegradable solid lipids such as mono-, di-, and triglycerides, fatty acids, waxes, and steroids, as well as lipophilic and hydrophilic ...
Rosa-Alejandra, Hernández-Esquivel, +3 more
openaire +2 more sources
Nanoporous silica-based protocells at multiple scales for designs of life and nanomedicine. [PDF]
, 2015 Various protocell models have been constructed de novo with the bottom-up approach. Here we describe a silica-based protocell composed of a nanoporous amorphous silica core encapsulated within a lipid bilayer built by self-assembly that provides for ...
Brinker, C Jeffrey +3 more
core +2 more sources
Nanoparticles-cell association predicted by protein corona fingerprints [PDF]
, 2016 In a physiological environment (e.g., blood and interstitial fluids) nanoparticles (NPs) will bind proteins shaping a "protein corona" layer. The long-lived protein layer tightly bound to the NP surface is referred to as the hard corona (HC) and encodes ...
Caracciolo, Giulio +6 more
core +3 more sources
A Comprehensive Review on Dry Eye Disease: Diagnosis, Medical Management, Recent Developments, and Future Challenges [PDF]
, 2015 Dry eye syndrome (DES) or keratoconjunctivitis sicca (KCS) is a common disorder of the tear film caused by decreased tear production or increased evaporation and manifests with a wide variety of signs and symptoms.
Askarkar, S +4 more
core +2 more sources