Results 41 to 50 of about 2,897,335 (282)

The use of quantitative analysis and Hansen solubility parameter predictions for the selection of excipients for lipid nanocarriers to be loaded with water soluble and insoluble compounds

Saudi Pharmaceutical Journal, 2020
The aim of these studies was to determine the miscibility of different API with lipid excipients to predict drug loading and encapsulation properties for the production of solid lipid nanoparticles and nanostructured lipid carriers.
Pedzisai A. Makoni, Janeeta Ranchhod, Kasongo WaKasongo, Sandile M. Khamanga, Roderick B. Walker   +4 more
doaj   +1 more source

Lipid Nanoparticles for Ocular Gene Delivery

Journal of Functional Biomaterials, 2015
Lipids contain hydrocarbons and are the building blocks of cells. Lipids can naturally form themselves into nano-films and nano-structures, micelles, reverse micelles, and liposomes.
Yuhong Wang, Ammaji Rajala, Raju V. S. Rajala   +2 more
doaj   +1 more source

Lipid Nanoparticles for the Posterior Eye Segment

Pharmaceutics, 2021
This review highlights the application of lipid nanoparticles (Solid Lipid Nanoparticles, Nanostructured Lipid Carriers, or Lipid Drug Conjugates) as effective drug carriers for pathologies affecting the posterior ocular segment. Eye anatomy and the most
Lorena Bonilla, Marta Espina, Patricia Severino, Amanda Cano, Miren Ettcheto, Antoni Camins, Maria Luisa García, Eliana B. Souto, Elena Sánchez-López   +8 more
doaj   +1 more source

Assessment of the Therapeutic Impact of Ivermectin Loaded on Solid Lipid Nanoparticles against Muscular Phase of Murine Trichinosis [PDF]

Zagazig University Medical Journal
Background: Trichinosis is acquired through ingesting the infective larvae in pork meat. Drugs employed for the treatment of trichinosis have a limited bioavailability in addition to the adverse side effects.
Tahani Farag, Mona Almotayam, Asmaa Mohamed, Al-Sayed R. Al-Attar, Ibrahim Aly, Shaimaa Farag, Samar Hammad   +6 more
doaj   +1 more source

Stability and antimicrobial effect of amikacin-loaded solid lipid nanoparticles [PDF]

, 2010
Solmaz Ghaffari1, Jaleh Varshosaz1, Afrooz Saadat2, Fatemeh Atyabi21Department of Pharmaceutics, Faculty of Pharmacy and Isfahan Pharmaceutical Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran; 2Department of Pharmaceutics,
Afrooz Saadat, et al, Jaleh Varshosaz, Solmaz Ghaffari   +3 more
core   +1 more source

SOLID LIPID NANOPARTICLES: A REVIEW

, 2023
Solid lipid nanoparticles (SLN) are at the forefront of the rapidly developing field of nanotechnology with several potential applications in drug delivery and research. Due to their unique size dependent properties, lipid nanoparticles offer possibility
Yerragopu Nagasurekha*, R Saravanan, Kole Shivakumar
core   +1 more source

New surface-modified solid lipid nanoparticles using N-glutaryl phosphatidylethanolamine as the outer shell

, 2011
Soheila Kashanian1, Abbas Hemati Azandaryani1, Katayoun Derakhshandeh2,3 1School of Chemistry, Nanoscience and Nanotechnology Research Center and Sensor and Biosensor Research Center, Razi University, 2Department of Pharmaceutics, Kermanshah University ...
Kashanian S, null Kashanian, Hemati Azandaryani A, Katayoun Derakhshandeh, Derakhshandeh K, Abbas Hemati Azandaryani   +5 more
core   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

FEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang, Ruslana Romaniuk, Hristo L. Svilenov   +2 more
wiley   +1 more source

SOLID LIPID NANOPARTICLES - EFFECT OF LIPID MATRIX AND SURFACTANT ON THEIR PHYSICAL CHARACTERISTICS [PDF]

Bulletin of Pharmaceutical Sciences. Assiut University, 2004
Solid lipid nanoparticles (SLN) have gained increasing attention as a colloidal drug carrier system, particularly for lipophilic drugs, because SLN combine the advantages of polymeric nanoparticles, fat emulsions, and liposomes but avoiding their ...
Mohamed Abdel-Moaty, Heba Abdel-Salam, Mamdouh Ghorab   +2 more
doaj   +1 more source

Going viral − Virus‐targeting nanobodies for research, diagnostics and therapy

FEBS Letters, EarlyView.
The increasing prevalence of viral diseases represents a major threat for global human health. Nanobodies, small binding fragments derived from camelid heavy‐chain antibodies, offer versatile tools for viral research, diagnostics, and antiviral therapy.
Domenic Ebert, Ulrich Rothbauer
wiley   +1 more source