Results 61 to 70 of about 56,129 (292)

Design, Preparation, and Characterization of Effective Dermal and Transdermal Lipid Nanoparticles: A Review

Cosmetics, 2021
Limited permeability through the stratum corneum (SC) is a major obstacle for numerous skin care products. One promising approach is to use lipid nanoparticles as they not only facilitate penetration across skin but also avoid the drawbacks of ...
Dima Khater, Hamdi Nsairat, Fadwa Odeh, Mais Saleh, Areej Jaber, Walhan Alshaer, Abeer Al Bawab, Mohammad S. Mubarak   +7 more
doaj   +1 more source

Aptamer‐Based Delivery Systems for VEGF and NGF Modulation in Ocular Therapies

Advanced Healthcare Materials, EarlyView.
Aptamer‐based delivery systems targeting NGF and VEGF hold significant potential for precise and sustained treatment of complex diseases affecting both the anterior and posterior segments of the eye. This review critically summarizes current strategies for NGF and VEGF delivery as well as VEGF sequestration, providing a clinical perspective on how ...
Nadine Best, Gizem Karabiyik, Gerd Geerling, Sarah Barbara Zwingelberg, Gregor Lang, Martin Humenik   +5 more
wiley   +1 more source

One‐Step Microfluidic Manufactured Fucose‐Decorated Sweetosomes Choose the Time and the Road for Their Intracellular Journey to Cancer Treatment

Advanced Healthcare Materials, EarlyView.
Sweetosomes, a new class of fucose‐decorated liposomes, are developed via a one‐step microfluidic process without surface chemistry. This study elucidates their main caveolae‐mediated entry and distinct endosomal trafficking. These nanostructures demonstrate superior endosomal escape, organelle acidity modulation, and prolonged plasma persistence ...
Mattia Tiboni, Mariele Montanari, Shiva Khorshid, Michele Verboni, Andrea Duranti, Simone Lucarini, Daniele Lopez, Annalisa Aluigi, Gianluca Morganti, Michele Menotta, Giovanna Panza, Daniel J. Klionsky, Barbara Canonico, Luca Casettari   +13 more
wiley   +1 more source

Lipid Nanoparticles for Drug Delivery

Advanced NanoBiomed Research, 2022
Lipid nanoparticles have attracted significant interests in the last two decades, and have achieved tremendous clinical success since the first clinical approval of Doxil in 1995.
Letao Xu, Xing Wang, Yun Liu, Guangze Yang, Robert J. Falconer, Chun-Xia Zhao   +5 more
doaj   +1 more source

Shellac‐Mediated Assembly of Nanoparticles for mRNA Delivery

Advanced Healthcare Materials, EarlyView.
A shellac‐mediated nanoparticle assembly strategy is presented, involving the complexation of mRNA and low‐molecular‐weight cationic molecules (e.g., polyethyleneimine, chitosan, lipids, and poly‐l‐lysine), followed by capping with shellac. This nanoparticle platform enables mRNA transfection following intravenous injection and facilitates gene editing
Meizhang Lu, Jingqu Chen, Zhixing Lin, Wanjun Xu, Tianzheng Wang, Shiyao Li, Die Yang, Frank Caruso   +7 more
wiley   +1 more source

A Review on Solid-lipid Nanoparticle

International Journal for Research in Applied Science and Engineering Technology, 2023
Abstract: Hydrophilic and hydrophobic medicines can both be carried by solid lipid nanoparticles (SLNs), which are solid core lipid nanocarriers. They are one of the favoured options for medication delivery since they may be constructed of components that are biocompatible.
openaire   +1 more source

THE Solid lipid nanoparticles A review

Journal of Drug Delivery and Therapeutics, 2019
Solid lipid nanoparticles are novel drug delivery system its to improve the solubility and bioavailability of the drug it has been proved that SLN is more effective colloidal drug delivery system  because of it is more controlled and targeting properties, the SLN as colloidal drug carriers for incorporating hydrophilic or lipophilic drugs, the ...
Ravindra Saudagar, Komal Harak, Prashant Patil   +2 more
openaire   +1 more source

Functional Blood‐Brain Barrier Crossing by Biomimetic M13 Phage Vectors for Targeted Neuronal Delivery

Advanced Healthcare Materials, EarlyView.
This study investigates the M13 bacteriophage as a biomimetic nanovector capable of crossing in vitro models of the blood–brain barrier. By exploiting peculiar transcellular pathways, M13 avoids lysosomal degradation and preserves its structural integrity and functionality.
Silvia Vercellino, Lucia Pappagallo, Francesca De Chirico, Luca Boselli, Hazem Ahmed, Luca Spagnoletti, Giovanni Pittaluga, Paolo Emidio Costantini, Matteo Calvaresi, Pier Paolo Pompa, Alberto Danielli, Fabio Benfenati, Valentina Castagnola   +12 more
wiley   +1 more source

Formulation and characterization of solid lipid nanoparticles loaded Neem oil for topical treatment of acne

Journal of Acute Disease, 2013
Objective: To investigate the treatment of acne and pimples as well as improves skin elasticity by solid lipid nanoparticles (SLNs) loaded Neem oil. Method: Neem oil as a natural agent was incorporated into SLNs prepared by double emulsification method ...
V. Vijayan, Shaik Aafreen, S. Sakthivel, K. Ravindra Reddy   +3 more
doaj   +1 more source

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

Journal of Nanobiotechnology, 2022
Liver cancer is considered one of the deadliest diseases with one of the highest disease burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is considered to be the most common type. Multiple conventional approaches are
Khaled Mahmoud, Shady Swidan, Mohamed El-Nabarawi, Mahmoud Teaima   +3 more
doaj   +1 more source