Results 61 to 70 of about 111,837 (204)

Lipid Nanoparticles for Drug Delivery

Advanced NanoBiomed Research, 2022
Lipid nanoparticles have attracted significant interests in the last two decades, and have achieved tremendous clinical success since the first clinical approval of Doxil in 1995.
Letao Xu, Xing Wang, Yun Liu, Guangze Yang, Robert J. Falconer, Chun-Xia Zhao   +5 more
doaj   +1 more source

Lysosomal tracking with red-fluorescent solid lipid nanoparticles

OpenNano, 2022
Lysosomes are organelles with many functions in cell metabolism, the morphology changes as a function of the different cellular mechanisms. Some enzymes in the lysosomal medium are responsible for the cellular digestion process.
Hellen Franciane Gonçalves Barbosa, Henrique Luis Piva, Antonio Claudio Tedesco   +2 more
doaj   +1 more source

Nanocarrier lipid composition modulates the impact of pulmonary surfactant protein B (SP-B) on cellular delivery of siRNA [PDF]

, 2019
Two decades since the discovery of the RNA interference (RNAi) pathway, we are now witnessing the approval of the first RNAi-based treatments with small interfering RNA (siRNA) drugs. Nevertheless, the widespread use of siRNA is limited by various extra-
De Backer, Lynn, De Smedt, Stefaan, Echaide, Mercedes, Guagliardo, Roberta, Merckx, Pieterjan, Pérez-Gil, Jesus, Raemdonck, Koen, Zamborlin, Agata   +7 more
core   +1 more source

Solid and liquid lipid-based binary solid lipid nanoparticles of diacerein: in vitro evaluation of sustained release, simultaneous loading of gold nanoparticles, and potential thermoresponsive behavior

International Journal of Nanomedicine, 2015
Mubashar Rehman,1 Asadullah Madni,1 Ayesha Ihsan,2 Waheed Samraiz Khan,2 Muhammad Imran Khan,1 Muhammad Ahmad Mahmood,1 Muhammad Ashfaq,1 Sadia Zafar Bajwa,2 Imran Shakir31Department of Pharmacy, Faculty of Pharmacy and Alternative Medicine, The Islamia ...
Rehman M, Madni A, Ihsan A, Khan WS, Khan MI, Mahmood MA, Ashfaq M, Bajwa SZ, Shakir I   +8 more
doaj  

Biophysicochemical interaction of a clinical pulmonary surfactant with nano-alumina

, 2015
We report on the interaction of pulmonary surfactant composed of phospholipids and proteins with nanometric alumina (Al2O3) in the context of lung exposure and nanotoxicity.
Berret, J. -F., Borgne, R. Le, Mousseau, F., Seyrek, E.   +3 more
core   +4 more sources

Solid lipid nanoparticles preparation and characterization. [PDF]

, 2009
The presents study aimed to prepare and characterize Solid Lipid Nanoparticles (SLNs) from palm oil materials. Hydrogenated palm oil and lecithin incorporated with surfactant were mixed and formed by High Pressure Homogenization (HPH) at elevated ...
Abdullah Al-Haj, Nagi Ahmed, Abdullah, Rasedee   +1 more
core   +1 more source

Solid lipid nanoparticles modified with stearic acid–octaarginine for oral administration of insulin

International Journal of Nanomedicine, 2012
Zhen-Hai Zhang,1,2 Yin-Long Zhang,2 Jian-Ping Zhou,2 Hui-Xia Lv21Jiangsu Province Academy of Traditional Chinese Medicine, Nanjing, China; 2Department of Pharmaceutics, China Pharmaceutical University, Nanjing, ChinaAbstract: The aim of this study was to
Zhang ZH, Zhang YL, Zhou JP, Lv HX
doaj  

Formulation and characterization of solid lipid nanoparticles loaded Neem oil for topical treatment of acne

Journal of Acute Disease, 2013
Objective: To investigate the treatment of acne and pimples as well as improves skin elasticity by solid lipid nanoparticles (SLNs) loaded Neem oil. Method: Neem oil as a natural agent was incorporated into SLNs prepared by double emulsification method ...
V. Vijayan, Shaik Aafreen, S. Sakthivel, K. Ravindra Reddy   +3 more
doaj   +1 more source

Mechanism of cellular uptake of genotoxic silica nanoparticles. [PDF]

, 2012
Mechanisms for cellular uptake of nanoparticles have important implications for nanoparticulate drug delivery and toxicity. We have explored the mechanism of uptake of amorphous silica nanoparticles of 14 nm diameter, which agglomerate in culture medium ...
Brown, AP, Hondow, NS, Jeuken, LJ, Krzemiński, L, Mu, Q, Routledge, MN   +5 more
core   +3 more sources

Lipid based nanoparticles as a novel treatment modality for hepatocellular carcinoma: a comprehensive review on targeting and recent advances

Journal of Nanobiotechnology, 2022
Liver cancer is considered one of the deadliest diseases with one of the highest disease burdens worldwide. Among the different types of liver cancer, hepatocellular carcinoma is considered to be the most common type. Multiple conventional approaches are
Khaled Mahmoud, Shady Swidan, Mohamed El-Nabarawi, Mahmoud Teaima   +3 more
doaj   +1 more source