Results 61 to 70 of about 2,725,499 (286)

Improved antibacterial function of Rifampicin-loaded solid lipid nanoparticles on Brucella abortus

Artificial Cells, Nanomedicine, and Biotechnology, 2019
The objective of this study was to assess the antibacterial activity of Rifampicin-loaded solid lipid nanoparticles on Brucella abortus 544. Rifampicin-loaded solid lipid nanoparticles were prepared by a modified microemulsion/sonication method and ...
Jalal Ghaderkhani, Rasoul Yousefimashouf, Mohammadreza Arabestani, Ghodratollah Roshanaei, Sara Soleimani Asl, Roghayeh Abbasalipourkabir   +5 more
doaj   +1 more source

THE Solid lipid nanoparticles A review

Journal of Drug Delivery and Therapeutics, 2019
Solid lipid nanoparticles are novel drug delivery system its to improve the solubility and bioavailability of the drug it has been proved that SLN is more effective colloidal drug delivery system  because of it is more controlled and targeting properties, the SLN as colloidal drug carriers for incorporating hydrophilic or lipophilic drugs, the ...
Ravindra Saudagar, Komal Harak, Prashant Patil   +2 more
openaire   +1 more source

A Review on Solid-lipid Nanoparticle

International Journal for Research in Applied Science and Engineering Technology, 2023
Abstract: Hydrophilic and hydrophobic medicines can both be carried by solid lipid nanoparticles (SLNs), which are solid core lipid nanocarriers. They are one of the favoured options for medication delivery since they may be constructed of components that are biocompatible.
openaire   +1 more source

Cellular Responses to Mechanical Cues Across Scales: From Fundamental Insights to Translational Potential

Advanced Healthcare Materials, EarlyView.
This review examines how cellular behavior is regulated by mechanical cues transmitted through soft biomaterials, from single‐cell mechanosensing to tissue‐level adaptation. It highlights why physiological relevance, rather than model complexity alone, is critical for translational mechanobiology and introduces a scoring framework linking material ...
Mathias Polz, Manuel P. Kainz, Niklas Haider, Theresa Rienmüller, Kerstin Lenk, Rupert Kargl, Michele Terzano, Gerhard Sommer, Gerhard A. Holzapfel, Julia Fuchs   +9 more
wiley   +1 more source

Automatic solid-phase synthesis of molecularly imprinted nanoparticles (MIP NPs) [PDF]

, 2012
Molecularly Imprinted Polymers (MIPs) are potential generic alternatives to antibodies in diagnostics and separations. To compete with biomolecules in these technological niches, MIPs need to share the characteristics of antibodies (solubility, size ...
Poma, Alessandro
core   +5 more sources

Mitochondria‐Targeted Nanotherapies in Aging Neurodegenerative Disorders: Emerging Prospects and Clinical Potential

Advanced Healthcare Materials, EarlyView.
Mitochondria‐targeted nanotherapies emerge as a promising strategy for combating aging‐associated neurodegenerative disorders (NDs) by restoring mitochondrial function, reducing oxidative stress, and improving neuronal survival. Recent advances in nanotechnology, therapeutic delivery, and translational research are highlighted, providing insights into ...
Dnyandev G. Gadhave, Ashish B. Jadhav, Nitin B. Waghamode, Shubham Khot, Rajiya Khan, Ravi Hole, Shankar M. Dhobale, Manoj Aswar, Keshav Raj Paudel   +8 more
wiley   +1 more source

Making the Case for Organ‐on‐Chip Platforms in Long‐Acting Therapeutics Development

Advanced Healthcare Materials, EarlyView.
LATs release drug from a tissue‐resident depot over weeks to months, improving adherence, but their development is hampered by preclinical models that cannot reproduce the coupled tissue processes, sustained release, local microenvironment change, interstitial transport, immune and foreign‐body responses, and clearance that govern depot performance in ...
Charlie Gowans, Abdulwahhab Khedr, Panagiotis G. Georgiou, Nehir Arik, Ozlem Sen, Steve P. Rannard, Tom O. McDonald, Christos Tapeinos   +7 more
wiley   +1 more source

PREPARATION AND CHARACTERIZATION OF SOLID LIPID MICRO/NANOPARTICLES I. EFFECT OF LIPID CONCENTRATION, SURFACTANT TYPE AND CONCENTRATION ON PHYSICAL CHARACTERISTICS OF SOLID LIPID MICRO/NANOPARTICLES

Zagazig Journal of Pharmaceutical Sciences, 2010
The objective of this study was to determine the best conditions to formulate solid lipid Nanoparticles using Glycery1 monostearate as lipid matrix which has advantage to be biocompatible and easily degraded in vivo.
Ahmed Gardouh , Hussein Sayed , Mamdouh Ghorab , Shaded Abdel-Rahman   +3 more
doaj   +1 more source

Innovative Agents for Actinic Keratosis and Nanocarriers Enhancing Skin Penetration [PDF]

, 2010
Actinic keratosis and cutaneous squamous cell carcinoma are of increasing importance with aging and increased ultraviolet light exposure in Western societies. Efficient and well-tolerated therapy is still a matter of concern.
Korting, Hans Christian, Schäfer-Korting, Monika, Höltje, M., Höltje, H.-D.   +3 more
core   +1 more source

From Cell‐Derived Vesicles to Hybrid Nanovectors: Biological Membranes as Functional Blueprints for Gene Delivery

Advanced Healthcare Materials, EarlyView.
Biologically derived and hybrid nonviral nanovectors are examined as distinct but convergent design approaches. Integrating synthetic components with biologically functionalized membranes allows efficient interactions with complex cellular environments.
Clara Baldari, Claudia Leone, Gabriella Leccese, Claudia De Stradis, Alessandra Invidia, Concetta Quintarelli, Biagio De Angelis, Franco Locatelli, Giuseppe Gigli, Gabriele Maiorano, Ilaria Elena Palamà   +10 more
wiley   +1 more source