Results 21 to 30 of about 2,897,335 (282)

Preparation and characterization of solid lipid nanoparticles loaded with frankincense and myrrh oil [PDF]

International Journal of Nanomedicine, 2012
Feng Shi, Ji-Hui Zhao, Ying Liu, Zhi Wang, Yong-Tai Zhang, Nian-Ping FengSchool of Pharmacy, Shanghai University of Traditional Chinese Medicine, Shanghai, People's Republic of ChinaAbstract: The aim of the present study was to prepare solid ...
Shi F, Zhao JH, Liu Y, Wang Z, Zhang YT, Feng NP   +5 more
doaj   +1 more source

Solid Lipid Nanoparticles (SLN): Formulation and Fabrication

Pharmaceutical Sciences and Research, 2023
Solid lipid nanoparticles (SLN) have emerged as a novel drug delivery system and have been utilized for delivering various kinds of drugs since the 1990s. These particles may consist of multiple solid lipids, including glycerides, waxes, and fatty acids,
Gabriella F. Punu, Yahdiana Harahap, Qonita Kurnia Anjani, Pietradewi Hartrianti, Ryan F. Donnelly, Delly Ramadon   +5 more
doaj   +1 more source

On the Structure of Solid Lipid Nanoparticles [PDF]

Small, 2019
AbstractSolid lipid nanoparticles (SLNs) have a crystalline lipid core which is stabilized by interfacial surfactants. SLNs are considered favorable candidates for drug delivery vehicles since their ability to store and release organic molecules can be tailored through the identity of the lipids and surfactants used.
Demi L. Pink, Orathai Loruthai, Robert M. Ziolek, Prawarisa Wasutrasawat, Ann E. Terry, M. Jayne Lawrence, Christian D. Lorenz   +6 more
openaire   +2 more sources

Central Composite Design for Formulation and Optimization of Solid Lipid Nanoparticles to Enhance Oral Bioavailability of Acyclovir

Molecules, 2021
Treatment of herpes simplex infection requires high and frequent doses of oral acyclovir to attain its maximum therapeutic effect. The current therapeutic regimen of acyclovir is known to cause unwarranted dose-related adverse effects, including acute ...
Haniza Hassan, Siti Khadijah Adam, Ekram Alias, Meor Mohd Redzuan Meor Mohd Affandi, Ahmad Fuad Shamsuddin, Rusliza Basir   +5 more
doaj   +1 more source

Ultrasmall Solid-Lipid Nanoparticles via the Polysorbate Sorbitan Phase-Inversion Temperature Technique: A Promising Vehicle for Antioxidant Delivery into the Skin

Pharmaceutics, 2023
Solid lipid nanoparticles promote skin hydration via stratum corneum occlusion, which prevents water loss by evaporation, and via the reinforcement of the skin’s lipid-film barrier, which occurs through the adhesion of the nanoparticles to the stratum ...
Francesca Della Sala, Assunta Borzacchiello, Chiara Dianzani, Elisabetta Muntoni, Monica Argenziano, Maria Teresa Capucchio, Maria Carmen Valsania, Annalisa Bozza, Sara Garelli, Maria Di Muro, Franco Scorziello, Luigi Battaglia   +11 more
doaj   +1 more source

Preclinical Evaluation of Lipid-Based Nanosystems

Pharmaceutics, 2021
The use of lipid-based nanosystems, including lipid nanoparticles (solid lipid nanoparticles—SLN, and nanostructured lipid carriers—NLC), nanoemulsions, and liposomes, among others, is widespread [...]
Ana Catarina Silva, José Manuel Sousa Lobo   +1 more
doaj   +1 more source

Formulation and Characterization of Phytostanol Ester Solid Lipid Nanoparticles for the Management of Hypercholesterolemia: An ex vivo Study [PDF]

, 2021
Background: Phytostanols are naturally occurring compounds that reduce blood cholesterol levels significantly. However, their aqueous insolubility poses formulation challenges.
White, K., Ghebremeskel, K., Shrestha, S., Minelli, C., White, Kenneth, Minelli, Caterina, Tewfik, Sundus, Tewfik, Ihab, Shrestha, Sony C., Tewfik, S., Thapa, Panna, Ghebremeskel, Kebreab, Tewfik, I.   +12 more
core   +1 more source

Lipid Nanoparticles Functionalized with Antibodies for Anticancer Drug Therapy

Pharmaceutics, 2023
Nanotechnology takes the lead in providing new therapeutic options for cancer patients. In the last decades, lipid-based nanoparticles—solid lipid nanoparticles (SLNs), nanostructured lipid carriers (NLCs), liposomes, and lipid–polymer hybrid ...
Ana Camila Marques, Paulo C. Costa, Sérgia Velho, Maria Helena Amaral   +3 more
doaj   +1 more source

Editorial—Current Insights on Lipid-Based Nanosystems

Pharmaceuticals, 2022
Lipid-based nanosystems, including solid lipid nanoparticles (SLN) and nanostructured lipid carriers (NLC), cationic lipid nanoparticles, nanoemulsions and liposomes, have been extensively studied to improve drug delivery through different administration
Ana Catarina Silva, João Nuno Moreira, José Manuel Sousa Lobo   +2 more
doaj   +1 more source

Solid Lipid Nanoparticles: A Potential Approach for Dermal Drug Delivery [PDF]

, 2014
Solid lipid nanoparticles (SLNs) have attracted increasing attention during recent years. Due to their unique size dependent properties, lipid nanoparticles offer possibilities to develop new therapeutics.
Conway, Barbara R, Kakadia, Pratibha G., Kakadia, Partibha, Conway, Barbara; id_orcid   +3 more
core   +1 more source