Results 91 to 100 of about 10,284 (151)

Is preoperative imaging of sentinel lymph node in breast cancer necessary? A retrospective case control study

Breast
Objective: The necessity of preoperative lymphoscintigraphy before intraoperative sentinel lymph node (SLN) identification is still unclear. The aim of the present study was to evaluate the impact of SLN imaging on intraoperative SLN detection in breast ...
Michael J. Reinhardt, Björn Ohmstede, Luz Angela Torres-de la Roche, Rudy Leon De Wilde   +3 more
doaj   +1 more source

Solid Lipid Nanoparticles Loading Idebenone Ester with Pyroglutamic Acid: In Vitro Antioxidant Activity and In Vivo Topical Efficacy

Nanomaterials, 2018
Idebenone (IDE), a strong antioxidant widely investigated for the treatment of neurodegenerative diseases and skin disorders, shows low oral and topical bioavailability due to its unfavorable physico-chemical properties.
Lucia Montenegro, Anna Maria Panico, Ludovica Maria Santagati, Edy Angela Siciliano, Sebastiano Intagliata, Maria N. Modica   +5 more
doaj   +1 more source

Merkel cell carcinoma: an updated guide for pathologists

Histopathology, EarlyView.
Merkel cell carcinoma (MCC) is an aggressive cutaneous neuroendocrine carcinoma for which the differential diagnosis can include other small cell malignancies (especially metastatic small cell carcinoma) or cutaneous carcinoma. Morphologic and immunophenotypic aberrancies in MCC can increase diagnostic challenge.
Paul W. Harms
wiley   +1 more source

Minimal prognostic significance of sentinel lymph node metastasis in patients with cT1–2 and cN0 breast cancer

World Journal of Surgical Oncology, 2019
Background The prognostic value of sentinel lymph node (SLN) metastases may be minimized by the limited disease burden of lymph node metastases and tailoring adjuvant therapy based on breast cancer biology.
Hideo Shigematsu, Mai Nishina, Daisuke Yasui, Taizo Hirata, Shinji Ozaki   +4 more
doaj   +1 more source

The Biological Basis of the Merlin CP‐GEP Assay: Integrin Signaling and Early Metastatic Competence in Cutaneous Melanoma

International Journal of Dermatology, EarlyView.
Merlin CP‐GEP integrates mechanistic insights into a clinically actionable assay to predict SLN metastasis risk and inform personalized management of cutaneous melanoma. ABSTRACT The recent inclusion of the Merlin clinicopathologic–gene expression profile (CP‐GEP) assay in the National Comprehensive Cancer Network (NCCN) Melanoma Guidelines represents ...
Frank Z. Jing, Alexander Meves
wiley   +1 more source

Stated SLn-skein Theory

The stated SLn-skein module Sn(M, N , v) of a (marked) 3-manifold (M, N ) is a quantization of the regular function ring of the SLn-representation variety of π1(M, N ). It is a module over a commutative domain R with an invertible parameter v.
Wang, Zhihao
core   +1 more source

Effect of Surfactant on Characteristics of Solid Lipid Nanoparticles (SLN)

, 2011
SLN have shown a great promise as an alternative drug carrier for intravenous and dermal applications. This work focuses on the basic properties of drug-free Compritol® ATO 888 based SLN systems by using cationic surfactant (CPC) and nonionic surfactant (
Siwaporn Meejoo Smith, Ruktanonchai Uracha, Karn Orachai Kullavadee   +2 more
core   +1 more source

Best Case/Worst Case: A Multisite Randomized Trial of Scenario Planning for Patients With Late‐Stage Kidney Disease

Journal of the American Geriatrics Society, EarlyView.
Best Case/Worst Case is a communication tool that uses scenario planning to support nephrologists and older adults with advanced chronic kidney disease as they make decisions about life with or without dialysis. ABSTRACT Background Best Case/Worst Case (BC/WC) is a communication tool to support nephrologists and older adults with advanced chronic ...
Lily N. Stalter, Bret M. Hanlon, Kyle J. Bushaw, Jenna Nitkowski, Anne Buffington, Katharine L. Cheung, Amy B. Zelenski, Kristine Kwekkeboom, Amar D. Bansal, Deidra Candice Crews, Holly M. Koncicki, Daniel Lam, Alvin H. Moss, Maya K. Rao, Dawn Felicity Wolfgram, Jeniann Yi, Carrie Brill, Tamara Isakova, Margaret L. Schwarze   +18 more
wiley   +1 more source

Genome‐wide association study of morphometric and metabolic characteristics in European populations of the sugar kelp Saccharina latissima

Journal of Phycology, EarlyView.
Abstract The sugar kelp Saccharina latissima is a promising candidate for sustainable aquaculture in the North Atlantic and Northeast Pacific, but genetic improvement has been hindered by a limited understanding of the genetic basis of economically important traits.
Stéphane Mauger, Komlan Avia, Lucie Jaugeon, Paolo Ruggeri, Zofia Nehr, Ousseini Issaka Salia, Jérôme Coudret, Emilie Gouhier, Aurélien Baud, Stéphane Loisel, Antoine Fort, Ronan Sulpice, Christophe Destombe, Philippe Potin, J. Mark Cock, Myriam Valero   +15 more
wiley   +1 more source