Results 131 to 140 of about 1,049,594 (310)

Three dimensional slope stability analyses for natural and manmade slopes [PDF]

, 2011
Item released from any restrictions by Sarah Shreeves (sshreeve@illinois.edu) on 2013-05-26T10:00:17ZSlope stability analyses in practice mostly rely on limit equilibrium (LE) procedures rather than finite element (FE) or finite difference (FD ...
Akhtar, Kamran
core  

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Sunny Slope, Freedom, Okla. : a report to the nation. [PDF]

, 1942
A scrapbook depicting war-related student activities in Oklahoma schools during the Second World ...
Sunny Slope (Freedom, Okla.)
core  

Wavefront analysis from its slope data

, 2017
In the aberration analysis of a wavefront over a certain domain, the polynomials that are orthogonal over and represent balanced wave aberrations for this domain are used.
Eva Acosta, Mahajan, Virendra N., Virendra N. Mahajan, Acosta, Eva   +3 more
core   +1 more source

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Slippery Slope [PDF]

The American Journal of Sports Medicine, 2019
openaire   +2 more sources

Alaskan North Slope oil in national perspective [PDF]

Petroleum industry and trade ...
Yvonne Levy
core  

Spatial biology in cancer epigenetics

Molecular Oncology, EarlyView.
Spatial epigenomics combines molecular profiling with tissue architecture to reveal how gene regulation is organized within intact tissues. In cancer, these technologies uncover the mechanisms driving tumor heterogeneity and microenvironmental interactions, opening new opportunities for biomarker discovery and precision medicine.
Eva Crespo‐García, Manel Esteller
wiley   +1 more source

Identification of Complex Slope Subsurface Strata Using Ground-Penetrating Radar

Remote Sensing
Identification of slope subsurface strata for natural soil slopes is essential to assess the stability of potential landslides. The highly variable strata in a slope are hard to characterize by traditional boreholes at limited locations.
Tiancheng Wang, Wensheng Zhang, Jinhui Li, Da Liu, Limin Zhang   +4 more
doaj   +1 more source

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

Molecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu, Yubei He, Nikolaus Berndt, Michael Mülleder, Kathrin Textoris‐Taube, Jing Guo, Matthias Stechele, Justus Ramtke, Shraga Nahum Goldberg, Lynn Jeanette Savic   +9 more
wiley   +1 more source