Results 51 to 60 of about 636,370 (268)
Degradation mechanism of the von Willebrand factor A2 domain by nattokinase
FEBS Letters, EarlyView.Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto +3 more
wiley +1 more source
Influence of Slope Height and Slope Ratio on Reliability of Channel Slopes
Guan'gai paishui xuebao, 2023 【Background】 Slope height and slope ratio are the most important design parameters affecting slope stability. This paper investigates their combined impact on reliability of channel slopes in attempt to help optimize design and remediation of such slopes.
ZHU Lei, GAO Xinyue, WAN Yukuai
openaire +1 more source
Efficacy of deterrents for mitigating human‐polar bear conflict in northern Alaska
Wildlife Society BulletinA warming climate is negatively affecting Arctic species that rely on sea ice to perform their life history activities. Changing sea ice dynamics have led polar bears in many subpopulations to spend more time on land, increasing the potential for human ...
Susanne Miller +5 more
doaj +1 more source
Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations
FEBS Letters, EarlyView.The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas +6 more
wiley +1 more source
Influence of Alpine Forest Types on Soil Microbial Diversity and Soil Quality
PlantsAlpine forests are key regulators of soil biogeochemical cycles, yet the extent to which forest type constrains soil microbial diversity and soil quality in high-elevation regions remains insufficiently resolved.
Shuang Ji +4 more
doaj +1 more source
Flood Potential Zonation Using Analytic Hierarchy Process in Kurdistan Province [PDF]
محیط زیست و مهندسی آبPreparation of flood zoning maps is one of the primary and necessary measures in the management of flood prone areas. In this study, analytic hierarchy process, and geographic information system were used to assess and zoning the flood potential map in ...
Bahar Akrami Moghadam +2 more
doaj +1 more source
FEBS Letters, EarlyView.An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley +1 more source
Industrial Crops and ProductsAs a widely cultivated perennial turfgrass, seashore paspalum (Paspalum vaginatum Sw.) exhibits plasticity in biomass allocation and stress tolerance phenotypes, with growth-resistance trade-offs critically influenced by light intensity.
Xiaowei Ding +6 more
doaj +1 more source
FEBS Letters, EarlyView.The physical dimensions and shape of bacterial cells define the surface area available to acquire nutrients and the volume available for synthesizing proteins and DNA. Here, we use computational systems biology to decode the importance of cell geometry as a major determinant of prokaryotic phenotype, including growth rate and metabolic efficiency. This
Ross P. Carlson +6 more
wiley +1 more source