Results 71 to 80 of about 1,049,594 (310)
Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis
FEBS Letters, EarlyView.Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee +7 more
wiley +1 more source
Modelling stem cell differentiation related processes—A practical overview for biologists
FEBS Letters, EarlyView.Stem cell differentiation is complex and difficult to control experimentally. This review introduces suitable computational modelling approaches that can support stem cell research, from mechanistic ODE and abstract models to multiscale and deep learning methods.
Ricco Zeegelaar +4 more
wiley +1 more source
FEBS Letters, EarlyView.Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani +3 more
wiley +1 more source
Efficacy of deterrents for mitigating human‐polar bear conflict in northern Alaska
Wildlife Society BulletinA warming climate is negatively affecting Arctic species that rely on sea ice to perform their life history activities. Changing sea ice dynamics have led polar bears in many subpopulations to spend more time on land, increasing the potential for human ...
Susanne Miller +5 more
doaj +1 more source
Influence of Slope Height and Slope Ratio on Reliability of Channel Slopes
Guan'gai paishui xuebao, 2023 【Background】 Slope height and slope ratio are the most important design parameters affecting slope stability. This paper investigates their combined impact on reliability of channel slopes in attempt to help optimize design and remediation of such slopes.
ZHU Lei, GAO Xinyue, WAN Yukuai
openaire +1 more source
, 2007 this paper, two methods are developed for determining the global slope of the word image. The first method estimates the slope by finding the minimum entropy in the vertical projection histograms, whereas the second method determines the slope from the ...
Slope Correction
core
Investigating transcription factor dynamics in health and disease using FRAP
FEBS Letters, EarlyView.FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj +3 more
wiley +1 more source
Influence of Alpine Forest Types on Soil Microbial Diversity and Soil Quality
PlantsAlpine forests are key regulators of soil biogeochemical cycles, yet the extent to which forest type constrains soil microbial diversity and soil quality in high-elevation regions remains insufficiently resolved.
Shuang Ji +4 more
doaj +1 more source
, 2019 This chapter introduces major landslide causes and triggers and outlines the principles of slope stability analysis for rock mass. It discusses the slope stability at the project site with considerations of different ground water conditions. Depending on
Gratchev, Ivan, Ivan Gratchev
core +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source