Results 41 to 50 of about 1,345,648 (320)

Stability and Countermeasures for a Deposit Slope with Artificial Scarp: Numerical Analysis and Field Monitoring

Advances in Civil Engineering, 2020
This paper presents the results of the stability analysis of a deposit slope with an artificial scarp in a tunnel exit and an evaluation of the effectiveness of four proposed reinforcement schemes.
Yong Hong, Zhushan Shao, Guangbin Shi, Jiabao Liu   +3 more
doaj   +1 more source

Monitoring Errors of Semi-Mechanized Coffee Planting by Remotely Piloted Aircraft

Agronomy, 2021
Mechanized operations on terrain slopes can still lead to considerable errors in the alignment and distribution of plants. Knowing slope interference in semi-mechanized planting quality can contribute to precision improvement in decision making, mainly ...
Lucas Santos Santana, Gabriel Araújo e Silva Ferraz, João Paulo Barreto Cunha, Mozarte Santos Santana, Rafael de Oliveira Faria, Diego Bedin Marin, Giuseppe Rossi, Leonardo Conti, Marco Vieri, Daniele Sarri   +9 more
doaj   +1 more source

A novel haptic model and environment for maxillofacial surgical operation planning and manipulation [PDF]

, 2012
This paper presents a practical method and a new haptic model to support manipulations of bones and their segments during the planning of a surgical operation in a virtual environment using a haptic interface. To perform an effective dental surgery it is
Arnez, Victor, Corney, Jonathan, Govea-Valladares, E., Hernandez, Ernesto, Li, Youhua, Lim, T., Villela, V., Yan, Xiu   +7 more
core   +1 more source

CDK11 inhibition induces cytoplasmic p21WAF1 splice variant by p53 stabilisation and SF3B1 inactivation

Molecular Oncology, EarlyView.
CDK11 inhibition stabilises the tumour suppressor p53 and triggers the production of an alternative p21WAF1 splice variant p21L, through the inactivation of the spliceosomal protein SF3B1. Unlike the canonical p21WAF1 protein, p21L is localised in the cytoplasm and has reduced cell cycle‐blocking activity.
Radovan Krejcir, Lukasz Arcimowicz, Lucia Martinkova, Vaclav Hrabal, Filip Zavadil Kokas, Tomas Henek, Martina Kucerikova, Ondrej Bonczek, Pavlina Zatloukalova, Lenka Hernychova, Philip J. Coates, Borivoj Vojtesek, David P. Lane   +12 more
wiley   +1 more source

Dual targeting of RET and SRC synergizes in RET fusion‐positive cancer cells

Molecular Oncology, EarlyView.
Despite the strong activity of selective RET tyrosine kinase inhibitors (TKIs), resistance of RET fusion‐positive (RET+) lung cancer and thyroid cancer frequently occurs and is mainly driven by RET‐independent bypass mechanisms. Son et al. show that SRC TKIs significantly inhibit PAK and AKT survival signaling and enhance the efficacy of RET TKIs in ...
Juhyeon Son, Lily L. Remsing Rix, Bin Fang, Eric A. Welsh, Nicole V. Bremer, Valentina Foglizzo, Paola Roa, Nickole Sigcha‐Coello, Yi Liao, Eric B. Haura, Alexander Drilon, John M. Koomen, Emiliano Cocco, Uwe Rix   +13 more
wiley   +1 more source

Analysis on slope stability by anchorage based on soil creep with flood effect

Heliyon
In order to analyze the adverse effect of flood affection on slope stability, the analytical expressions of buoyancy force and capillary force, hydrodynamic pressure and impact force, and scour erosion were proposed based on the aging characteristics of ...
Jun Wang, Lin Liu
doaj   +1 more source

Effective inertial frame in an atom interferometric test of the equivalence principle

, 2017
In an ideal test of the equivalence principle, the test masses fall in a common inertial frame. A real experiment is affected by gravity gradients, which introduce systematic errors by coupling to initial kinematic differences between the test masses. We
Asenbaum, Peter, Hogan, Jason M., Kasevich, Mark A., Kovachy, Tim, Notermans, Remy, Overstreet, Chris   +5 more
core   +1 more source

Simple slope compensator for Ku-band applications.

, 1997
The present paper describes a simple circuital solution for a slope compensation function to be used in an amplification chain when it is necessary to recover for both fast ripple and slope variation occurred within the whole bandwidth. The circuit has been studied and developed mainly for Ku-Band applications and has been implemented in MMIC form ...
Feudale, M., Suriani, A.
openaire   +2 more sources

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Slope Compensation and Bifurcation in a DC-DC, Single-Input, Multiple-Output, CMOS Integrated Converter Under Current-Mode and Comparator-Based Hybrid Control

Journal of Low Power Electronics and Applications
Single-Input, Multi-Output (SIMO) converters present significant challenges when operated under current-mode control, due to their strongly non-linear dynamics and susceptibility to bifurcation phenomena. To mitigate the effects on the converter’s steady-
Mathieu Ginet, Eric Feltrin, Nicolas Jeanniot, Bruno Allard, Xuefang Lin-Shi   +4 more
doaj   +1 more source