Results 71 to 80 of about 4,140,671 (254)

Extracellular matrix remodeling and immune reprogramming drive residual tumor progression of liver cancer after incomplete microwave ablation

open access: yesMolecular Oncology, EarlyView.
Incomplete microwave ablation (iMWA) of liver cancer triggers a biphasic progression in residual tumors. At Day 3, the microenvironment is characterized by acute inflammatory responses and extracellular matrix (ECM) remodeling. By Day 14, a profound shift occurs toward oncogenic signal transduction and immunosuppression, marked by macrophage ...
Yu Liu   +9 more
wiley   +1 more source

Occurrence Characteristics and Preventions of the Debris Flow on Slope in the Lower Reaches Zagunao River

open access: yesShuitu baochi yanjiu, 2013
Base on the research of the downstream region of Zagunao River,the arid valley slope debris flow conditions,the process of formation mechanism of the solid material,and the affection mechanism of the different marerials were analyzed.The slope mud rock ...
HUANG Hai   +2 more
doaj  

Flow regime transformation and reservoir architecture difference of lacustrine gravity flows controlled by a slope break zone: A case study from Moxizhuang area, Junggar Basin

open access: yesYouqi dizhi yu caishoulu
The second Member of the lower Jurassic Sangonghe Formation in the deep Moxizhuang-Yongjin area, the center of the Junggar Basin, has long been interpreted as a braided river delta depositional system.
TAN Xingyu
doaj   +1 more source

Engineering IL‐4 resistant proinflammatory human myeloid cells for cancer immunotherapy

open access: yesMolecular Oncology, EarlyView.
We developed a scalable workflow to generate proinflammatory human myeloid cells. CRISPR/Cas9‐edited CD34+ hematopoietic stem and progenitor cells were expanded and differentiated with M‐CSF. Deletion of STAT6 or STAT6/NFKB1 enhanced macrophage proinflammatory gene expression and cytokine secretion in the presence of IL‐4 while maintaining antibody ...
Theresa Barberi, Alan D. Friedman
wiley   +1 more source

Contributions of flow discharge, slope gradient, and scouring time on rill erosion: A quantitative study of exposed slopes in the loess region

open access: yesInternational Journal of Sediment Research
Flow discharge, slope gradient, and erosion time are widely recognized as crucial factors in determining rill erosion and its morphological characteristics.
Yang Li   +4 more
doaj   +1 more source

The sediment transport capacity changing the relationship with slope gradients and flow discharge.

open access: yes, 2021
The sediment transport capacity changing the relationship with slope gradients and flow discharge.
Bai Yikui (11402234)   +3 more
core   +1 more source

Tumour‐proximal deep serum proteomics identifies biomarkers associated with ovarian cancer

open access: yesMolecular Oncology, EarlyView.
New biomarkers are needed for early ovarian cancer detection. Ovarian (tumour‐proximal) and peripheral vein serum from healthy women and patients with benign or malignant tumours underwent nanoparticle‐enriched deep proteomics. Ovarian serum yielded more protein identifications and revealed tumour‐reflective signatures.
Darren Lau   +9 more
wiley   +1 more source

Effect of slope position on the spatial distribution of soil preferential flow paths based on point pattern analysis.

open access: yesPLoS ONE
The mechanisms of soil preferential flow occurrence and development are influenced by topographic and geomorphological factors. However, the complex distribution patterns of soil preferential flow paths on different slopes remain unclear.
Mingfeng Li   +4 more
doaj   +1 more source

Attitudes of cancer patients toward ctDNA‐based liquid biopsy for follow‐up

open access: yesMolecular Oncology, EarlyView.
This mixed‐methods study explored cancer patients' experiences, knowledge, and preferences regarding ctDNA‐based liquid biopsy for follow‐up. Awareness of ctDNA was low and recall of previous liquid biopsy was imperfect, yet acceptance was high.
Siddharth Chhajlani   +7 more
wiley   +1 more source

Effects of Exposed Rock on Soil and Water Loss and Hydrodynamic Characteristics of Karst Slope Land

open access: yesShuitu Baochi Xuebao
[Objective] The effects of exposed rocks on the runoff, sediment yield, and hydrodynamic characteristics of slope land needs further study. [Methods] Through the laboratory simulation test, the slope lands with different rock exposure rates (0, 10%, 30%,
HE Maolin   +4 more
doaj   +1 more source

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