Dynamic Lysine Acetylation Disrupts Isocitrate Lyase Function and Enables Metabolic Optimisation
Acetyl‐phosphate–dependent acetylation of E. coli isocitrate lyase (ICL) at K13 and K308 inhibits its activity, while CobB‐mediated deacetylation restores function. Introducing K13R/K308R mutations enhances metabolic balance and increases lycopene yield by 61%, providing a promising approach to optimise microbial cell factories through natural ...
Adrián Martínez‐Vivancos +6 more
wiley +1 more source
Landslides along Himalayan Road corridors pose persistent threats to infrastructure due to steep terrain, intensely jointed rock masses, and continuous road-widening activities.
Virat Singh Chauhan +3 more
doaj +1 more source
Examining the factors underlying landslides and assessing the stability of slopes is crucial for reducing the negative impact of landslides on the environment and the lifespan of infrastructure.
Melkamie Kinde +2 more
doaj +1 more source
Análisis cinemático de dos taludes de macizo rocoso en la ciudad de Loja para conocer su grado de estabilidad. [PDF]
El trabajo de investigación presenta las características geo-mecánicas y la calidad de los macizos rocosos ubicados en el Barrio Teneria de la ciudad de Loja, donde el análisis de los resultados obtenidos permite obtener una visión real del estado del ...
Maza Guachisaca, Marjorie Michelle
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PRELIMINARY GEOMECHANICAL ANALYSIS ON LIMESTONES IN PPSDM GEOMINERBA CAMPUS, PADALARANG, WEST JAVA [PDF]
The research location is in the PPSDM Geominerba field campus. The campus is located in Padalarang, West Java that is surrounded by the open-pit mining of limestone and marble. This limestone was formed in Oligo-Miocene of Rajamandala Formation.
A, Abdurrokhim +5 more
core +2 more sources
Abstract Point sources are often major contributors of greenhouse gas and air pollutant emissions in urban areas. Dense air monitoring networks provide a unique avenue for studying point source emissions over long time periods. Here, we use the Berkeley Environmental Air‐quality and CO2 Network (BEACO2N) to study CO2 and air pollutant emissions from an
Milan Y. Patel +4 more
wiley +1 more source
Revisión del estado actual de la clasificación geomecánica Slope Mass Rating (SMR)
Slope Mass Rating (SMR) is a geomechanic classification used for the characterization of rocky slopes, which is calculated adjusting the basic RMR through several factors depending on: (a) the parallelism between the discontinuity and slope directions (F1); (b) the dip of the discontinuities (F2); (c) the relationship between the dip of the ...
Tomás, Roberto +2 more
openaire +1 more source
Slope Geometry Design Optimization in the Final Wall Pit Area of Sijebi PT. Solusi Bangun Indonesia Tbk, Narogong Factory, Bogor Regency [PDF]
Slope design is an important component that must be considered in open-pit mining. It affects mine safety as well as the maximization of mining activities. These two things have an inversely proportional relationship and must be optimized with each other.
Afwach, Atina - +2 more
core +2 more sources
Lereng merupakan galian terbuka yang memiliki kerentanan tinggi di dunia konstruksi terutama bendungan. Konstruksi galian pada litologi metamorf menjadi tantangan besar dalam menjaga keamanan dan stabilitas.
Bambang Hambar Eko Prasetyo +2 more
doaj +1 more source
ANALISIS KESTABILAN LERENG MENGGUNAKAN KLASIFIKASI MASSA BATUAN DENGAN METODE ROCK MASS RATING (RMR) DAN SLOPE MASS RATING (SMR) DI JALAN RAYA BANDA ACEH-MEULABOH KM 20 DAN KM 27 KEC.LEUPUNG, ACEH BESAR [PDF]
ABSTRAKLereng yang berada di samping jalan raya dengan adanya getaran beresikoterjadinya longsoran. Berdasarkan dari hasil penelitian yang dilakukan di lerengjalan raya KM 20 dan KM 27 Banda Aceh-Meulaboh KM 20 dan KM 27Kecamatan Leupung, Aceh Besar yang
NAUFAL EFFENDI
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